Top cofit genes for b2221 from Escherichia coli BW25113

atoD: acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI)
SEED: Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (EC 2.8.3.8)
KEGG: acetate CoA-transferase alpha subunit

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0101	yacG	zinc-binding protein (NCBI)	no	0.30
2	b2220	atoC	fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI)	0.50	0.29
3	b1635	gst	glutathionine S-transferase (NCBI)	no	0.29
4	b3360	pabA	para-aminobenzoate synthase component II (NCBI)	0.24	0.28
5	b4349	hsdM	DNA methylase M (NCBI)	0.21	0.28
6	b1345	intR	Rac prophage; integrase (NCBI)	0.25	0.26
7	b1963	b1963	orf, hypothetical protein (VIMSS)	no	0.25
8	b0389	yaiA	hypothetical protein (NCBI)	no	0.25
9	b1056	yceI	hypothetical protein (NCBI)	no	0.25
10	b4045	yjbJ	predicted stress response protein (NCBI)	no	0.25
11	b2456	cchB	predicted carboxysome structural protein, ethanolamine utilization protein (NCBI)	no	0.25
12	b3271	yhdZ	predicted amino-acid transporter subunit (NCBI)	no	0.24
13	b2632	yfjP	CP4-57 prophage; predicted GTP-binding protein (NCBI)	no	0.24
14	b1177	ycgJ	hypothetical protein (NCBI)	no	0.24
15	b2336	yfcS	predicted periplasmic pilus chaperone (NCBI)	no	0.24
16	b4333	yjiK	conserved protein (RefSeq)	no	0.23
17	b4686	yshB	expressed protein (RefSeq)	no	0.23
18	b0223	yafJ	predicted amidotransfease (NCBI)	no	0.23
19	b3136	agaS	tagatose-6-phosphate ketose/aldose isomerase (NCBI)	no	0.23
20	b0491	ybbM	putative metal resistance protein (VIMSS)	0.51	0.23

Or look for negative cofitness