Top cofit genes for b2221 from Escherichia coli BW25113

atoD: acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI)
SEED: Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (EC 2.8.3.8)
KEGG: acetate CoA-transferase alpha subunit

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0101	yacG	zinc-binding protein (NCBI)	no	0.29
2	b1635	gst	glutathionine S-transferase (NCBI)	no	0.27
3	b2220	atoC	fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI)	no	0.27
4	b3360	pabA	para-aminobenzoate synthase component II (NCBI)	0.24	0.26
5	b2456	cchB	predicted carboxysome structural protein, ethanolamine utilization protein (NCBI)	no	0.26
6	b1056	yceI	hypothetical protein (NCBI)	0.43	0.26
7	b0389	yaiA	hypothetical protein (NCBI)	no	0.25
8	b3698	yidB	orf, hypothetical protein (VIMSS)	no	0.24
9	b0491	ybbM	putative metal resistance protein (VIMSS)	0.45	0.24
10	b1881	cheZ	chemotaxis regulator, protein phosphatase for CheY (NCBI)	0.38	0.24
11	b3271	yhdZ	predicted amino-acid transporter subunit (NCBI)	no	0.24
12	b4349	hsdM	DNA methylase M (NCBI)	no	0.23
13	b2831	mutH	DNA mismatch repair protein (NCBI)	no	0.23
14	b2336	yfcS	predicted periplasmic pilus chaperone (NCBI)	no	0.23
15	b1963	b1963	orf, hypothetical protein (VIMSS)	no	0.23
16	b1345	intR	Rac prophage; integrase (NCBI)	no	0.23
17	b1177	ycgJ	hypothetical protein (NCBI)	no	0.22
18	b4045	yjbJ	predicted stress response protein (NCBI)	no	0.22
19	b1273	yciN	hypothetical protein (NCBI)	no	0.22
20	b3136	agaS	tagatose-6-phosphate ketose/aldose isomerase (NCBI)	no	0.22

Or look for negative cofitness