Top cofit genes for b2220 from Escherichia coli BW25113

atoC: fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI)
SEED: Acetoacetate metabolism regulatory protein AtoC
KEGG: two-component system, NtrC family, response regulator AtoC

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0251	yafY	CP4-6 prophage; predicted DNA-binding transcriptional regulator (RefSeq)	no	0.31
2	b1177	ycgJ	hypothetical protein (NCBI)	no	0.30
3	b0101	yacG	zinc-binding protein (NCBI)	no	0.29
4	b0576	pheP	phenylalanine transporter (NCBI)	no	0.29
5	b3360	pabA	para-aminobenzoate synthase component II (NCBI)	0.77	0.29
6	b4004	zraR	fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein (NCBI)	0.18	0.28
7	b1977	asnT	tRNA-Asn (NCBI)	no	0.27
8	b2332	b2332	orf, hypothetical protein (VIMSS)	no	0.27
9	b2221	atoD	acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI)	no	0.27
10	b2182	bcr	bicyclomycin/multidrug efflux system (NCBI)	no	0.27
11	b3698	yidB	orf, hypothetical protein (VIMSS)	no	0.26
12	b2495	yfgD	predicted oxidoreductase (NCBI)	no	0.26
13	b3136	agaS	tagatose-6-phosphate ketose/aldose isomerase (NCBI)	no	0.26
14	b4686	yshB	expressed protein (RefSeq)	no	0.25
15	b2456	cchB	predicted carboxysome structural protein, ethanolamine utilization protein (NCBI)	no	0.25
16	b4697	yrdF	no description	no	0.25
17	b0389	yaiA	hypothetical protein (NCBI)	no	0.25
18	b1635	gst	glutathionine S-transferase (NCBI)	no	0.25
19	b1419	ydcA	hypothetical protein (NCBI)	no	0.25
20	b1491	yddW	predicted liprotein (NCBI)	no	0.25

Or look for negative cofitness