Top cofit genes for b2049 from Escherichia coli BW25113

cpsB: mannose-1-phosphate guanyltransferase (NCBI)
SEED: Mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) / Mannose-6-phosphate isomerase (EC 5.3.1.8)
KEGG: mannose-1-phosphate guanylyltransferase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1817	manX	fused mannose-specific PTS enzymes: IIA component/IIB component (NCBI)	no	0.22
2	b1192	ldcA	L,D-carboxypeptidase A (NCBI)	0.93	0.19
3	b0032	carA	carbamoyl-phosphate synthase small subunit (NCBI)	0.78	0.19
4	b0934	ycbM	putative transport system permease protein (VIMSS)	no	0.19
5	b2763	cysI	sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI)	0.71	0.19
6	b2193	narP	DNA-binding response regulator in two-component regulatory system with NarQ or NarX (NCBI)	0.58	0.19
7	b0522	purK	phosphoribosylaminoimidazole carboxylase (NCBI)	0.68	0.18
8	b0306	ykgE	predicted oxidoreductase (NCBI)	no	0.18
9	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.76	0.18
10	b2762	cysH	phosphoadenosine phosphosulfate reductase (NCBI)	0.53	0.18
11	b3773	ilvY	DNA-binding transcriptional dual regulator (NCBI)	no	0.18
12	b0604	dsbG	thiol:disulfide interchange protein (VIMSS)	no	0.17
13	b1473	yddG	predicted methyl viologen efflux pump (RefSeq)	no	0.17
14	b4379	yjjW	predicted pyruvate formate lyase activating enzyme (NCBI)	no	0.17
15	b3939	metB	cystathionine gamma-synthase (NCBI)	0.75	0.17
16	b1819	manZ	mannose-specific enzyme IID component of PTS (NCBI)	no	0.17
17	b1467	narY	nitrate reductase 2 (NRZ), beta subunit (NCBI)	no	0.17
18	b4636	ybfI	no description	no	0.17
19	b1596	ynfM	predicted transporter (NCBI)	no	0.17
20	b4350	hsdR	endonuclease R (RefSeq)	0.22	0.17

Or look for negative cofitness