Top cofit genes for b2019 from Escherichia coli BW25113

hisG: ATP phosphoribosyltransferase (NCBI)
SEED: ATP phosphoribosyltransferase (EC 2.4.2.17)
KEGG: ATP phosphoribosyltransferase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.97	0.97
2	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.99	0.96
3	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.98	0.96
4	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.99	0.96
5	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.99	0.96
6	b2020	hisD	histidinol dehydrogenase (NCBI)	0.99	0.96
7	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.99	0.95
8	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.99	0.95
9	b0073	leuB	3-isopropylmalate dehydrogenase (VIMSS)	0.99	0.95
10	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.99	0.95
11	b2600	tyrA	fused chorismate mutase T/prephenate dehydrogenase (NCBI)	0.96	0.95
12	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.99	0.95
13	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.99	0.95
14	b3772	ilvA	threonine dehydratase (NCBI)	0.99	0.95
15	b0071	leuD	isopropylmalate isomerase small subunit (NCBI)	0.99	0.94
16	b3008	metC	cystathionine beta-lyase (NCBI)	0.97	0.94
17	b0242	proB	gamma-glutamyl kinase (NCBI)	0.99	0.93
18	b0243	proA	gamma-glutamyl phosphate reductase (NCBI)	0.99	0.93
19	b2750	cysC	adenylylsulfate kinase (NCBI)	0.90	0.93
20	b2023	hisH	imidazole glycerol phosphate synthase subunit HisH (NCBI)	0.99	0.93

Or look for negative cofitness