Top cofit genes for b1827 from Escherichia coli BW25113

kdgR: predicted DNA-binding transcriptional regulator (NCBI)
SEED: Transcriptional regulator KdgR, KDG operon repressor

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1702	pps	phosphoenolpyruvate synthase (NCBI)	0.46	0.41
2	b3991	thiG	thiamin biosynthesis, thiazole moiety (VIMSS)	0.42	0.30
3	b3994	thiC	thiamine biosynthesis protein ThiC (NCBI)	0.61	0.29
4	b3993	thiE	thiamine-phosphate pyrophosphorylase (NCBI)	no	0.29
5	b0912	ihfB	integration host factor subunit beta (NCBI)	0.25	0.28
6	b3992	thiF	thiamin biosynthesis, thiazole moiety (VIMSS)	no	0.28
7	b0052	pdxA	4-hydroxythreonine-4-phosphate dehydrogenase (NCBI)	no	0.27
8	b0390	aroM	hypothetical protein (NCBI)	no	0.27
9	b0075	leuL	leu operon leader peptide (NCBI)	0.66	0.27
10	b2103	thiD	phosphomethylpyrimidine kinase (NCBI)	no	0.26
11	b3990	thiH	thiamine biosynthesis protein ThiH (NCBI)	no	0.26
12	b2320	pdxB	erythronate-4-phosphate dehydrogenase (NCBI)	0.62	0.26
13	b3828	metR	DNA-binding transcriptional activator, homocysteine-binding (NCBI)	0.30	0.26
14	b2564	pdxJ	pyridoxal phosphate biosynthetic protein (NCBI)	no	0.24
15	b0889	lrp	DNA-binding transcriptional dual regulator, leucine-binding (NCBI)	0.64	0.24
16	b0223	yafJ	predicted amidotransfease (NCBI)	no	0.24
17	b2601	aroF	3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible (NCBI)	0.80	0.24
18	b3829	metE	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI)	0.45	0.24
19	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.34	0.23
20	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	no	0.23

Or look for negative cofitness