Top cofit genes for b1819 from Escherichia coli BW25113

manZ: mannose-specific enzyme IID component of PTS (NCBI)
SEED: PTS system, mannose-specific IID component
KEGG: PTS system, mannose-specific IID component

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1817	manX	fused mannose-specific PTS enzymes: IIA component/IIB component (NCBI)	0.58	0.76
2	b1818	manY	mannose-specific enzyme IIC component of PTS (NCBI)	0.59	0.57
3	b1820	yobD	hypothetical protein (NCBI)	0.50	0.39
4	b1613	manA	mannose-6-phosphate isomerase (VIMSS)	0.13	0.36
5	b1595	ynfL	predicted DNA-binding transcriptional regulator (NCBI)	0.14	0.29
6	b0014	dnaK	molecular chaperone DnaK (NCBI)	no	0.29
7	b1976	b1976	orf, hypothetical protein (VIMSS)	0.51	0.25
8	b3830	ysgA	predicted hydrolase (NCBI)	0.33	0.21
9	b4136	dipZ	thiol:disulfide interchange protein precursor (NCBI)	0.22	0.21
10	b0758	galT	galactose-1-phosphate uridylyltransferase (NCBI)	no	0.21
11	b0367	tauC	taurine transporter subunit (NCBI)	no	0.20
12	b1123	potD	spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI)	no	0.20
13	b1101	ptsG	fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI)	0.60	0.19
14	b0819	ybiS	hypothetical protein (NCBI)	0.50	0.19
15	b1692	ydiB	quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI)	no	0.18
16	b2167	fruA	fused fructose-specific PTS enzymes: IIBcomponent/IIC components (NCBI)	no	0.18
17	b1596	ynfM	predicted transporter (NCBI)	no	0.18
18	b4053	alr	alanine racemase (NCBI)	no	0.18
19	b3626	rfaJ	UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI)	no	0.17
20	b1429	tehA	potassium-tellurite ethidium and proflavin transporter (NCBI)	no	0.17

Or look for negative cofitness