Top cofit genes for b1746 from Escherichia coli BW25113

astD: succinylglutamic semialdehyde dehydrogenase (NCBI)
SEED: Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71)
KEGG: succinylglutamic semialdehyde dehydrogenase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1745	astB	succinylarginine dihydrolase (NCBI)	0.94	0.51
2	b1748	astC	succinylornithine transaminase, PLP-dependent (NCBI)	0.82	0.50
3	b1747	astA	arginine succinyltransferase (NCBI)	0.96	0.47
4	b1744	astE	succinylglutamate desuccinylase (NCBI)	0.89	0.24
5	b3375	yhfR	putative transcriptional regulator (VIMSS)	0.55	0.21
6	b1296	ycjJ	putative amino acid/amine transport protein (VIMSS)	0.43	0.20
7	b0450	glnK	nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI)	no	0.20
8	b0964	yccT	hypothetical protein (NCBI)	no	0.20
9	b3846	fadB	fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (NCBI)	no	0.19
10	b3075	ebgR	DNA-binding transcriptional repressor (NCBI)	no	0.19
11	b2681	ygaY	predicted transporter (pseudogene) (RefSeq)	no	0.19
12	b0019	nhaA	pH-dependent sodium/proton antiporter (NCBI)	0.35	0.19
13	b3236	mdh	malate dehydrogenase (NCBI)	0.82	0.18
14	b1376	ynaF	putative filament protein (VIMSS)	no	0.18
15	b1412	azoR	acyl carrier protein phosphodiesterase (NCBI)	no	0.18
16	b0726	sucA	alpha-ketoglutarate decarboxylase (NCBI)	no	0.18
17	b1612	fumA	fumarate hydratase (fumarase A), aerobic Class I (NCBI)	no	0.18
18	b1528	ydeA	sugar efflux transporter (NCBI)	0.50	0.18
19	b1221	narL	DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) (NCBI)	0.52	0.17
20	b2281	nuoI	NADH dehydrogenase subunit I (NCBI)	0.68	0.17

Or look for negative cofitness