Top cofit genes for b1744 from Escherichia coli BW25113

astE: succinylglutamate desuccinylase (NCBI)
SEED: Succinylglutamate desuccinylase (EC 3.5.1.96)
KEGG: succinylglutamate desuccinylase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3375	yhfR	putative transcriptional regulator (VIMSS)	0.40	0.27
2	b1748	astC	succinylornithine transaminase, PLP-dependent (NCBI)	0.73	0.26
3	b1746	astD	succinylglutamic semialdehyde dehydrogenase (NCBI)	0.88	0.25
4	b3075	ebgR	DNA-binding transcriptional repressor (NCBI)	no	0.24
5	b1745	astB	succinylarginine dihydrolase (NCBI)	0.78	0.23
6	b4139	aspA	aspartate ammonia-lyase (aspartase) (VIMSS)	0.63	0.23
7	b1747	astA	arginine succinyltransferase (NCBI)	0.77	0.22
8	b4020	yjbB	predicted transporter (NCBI)	no	0.21
9	b3601	mtlR	DNA-binding repressor (NCBI)	0.22	0.20
10	b3423	glpR	DNA-binding transcriptional repressor (NCBI)	0.42	0.19
11	b2648	pinH	predicted invertase fragment (pseudogene) (RefSeq)	no	0.19
12	b1084	rne	fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI)	no	0.18
13	b3438	gntR	DNA-binding transcriptional repressor (NCBI)	0.75	0.18
14	b2952	yggT	predicted inner membrane protein (NCBI)	no	0.18
15	b2626	yfjJ	CP4-57 prophage; predicted protein (NCBI)	no	0.18
16	b1581	rspA	predicted dehydratase (NCBI)	no	0.18
17	b3846	fadB	fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (NCBI)	0.23	0.17
18	b2647	ypjA	putative ATP-binding component of a transport system (VIMSS)	no	0.17
19	b3471	yhhQ	conserved inner membrane protein (NCBI)	no	0.17
20	b3038	ygiC	predicted enzyme (NCBI)	no	0.17

Or look for negative cofitness