Top cofit genes for b1608 from Escherichia coli BW25113

rstA: DNA-binding response regulator in two-component regulatory system with RstB (RefSeq)
SEED: Transcriptional regulatory protein RstA
KEGG: two-component system, OmpR family, response regulator RstA

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4075	nrfF	heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfF (NCBI)	no	0.25
2	b0601	ybdM	hypothetical protein (NCBI)	no	0.21
3	b1485	ddpC	D-ala-D-ala transporter subunit (NCBI)	0.45	0.21
4	b1056	yceI	hypothetical protein (NCBI)	0.23	0.21
5	b0980	appA	phosphoanhydride phosphorylase (NCBI)	no	0.20
6	b3476	nikA	nickel transporter subunit (NCBI)	no	0.20
7	b3479	nikD	nickel transporter subunit (NCBI)	0.49	0.19
8	b1225	narH	nitrate reductase 1, beta (Fe-S) subunit (NCBI)	no	0.19
9	b2712	hypF	carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases (NCBI)	0.40	0.18
10	b2730	hypE	carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein (RefSeq)	0.46	0.17
11	b3136	agaS	tagatose-6-phosphate ketose/aldose isomerase (NCBI)	no	0.17
12	b2490	b2490	putative protein processing element (VIMSS)	no	0.17
13	b0101	yacG	zinc-binding protein (NCBI)	no	0.17
14	b2700	ygaD	competence damage-inducible protein A (NCBI)	0.27	0.17
15	b4238	nrdD	anaerobic ribonucleoside triphosphate reductase (NCBI)	0.23	0.17
16	b2299	yfcD	predicted NUDIX hydrolase (NCBI)	no	0.17
17	b1820	yobD	hypothetical protein (NCBI)	no	0.16
18	b4053	alr	alanine racemase (NCBI)	no	0.16
19	b0517	allD	ureidoglycolate dehydrogenase (NCBI)	0.48	0.16
20	b4237	nrdG	anaerobic ribonucleotide reductase activating protein (NCBI)	0.41	0.16

Or look for negative cofitness