Top cofit genes for b1516 from Escherichia coli BW25113

lsrB: AI2 transporter (NCBI)
SEED: Autoinducer 2 (AI-2) ABC transport system, periplasmic AI-2 binding protein LsrB
KEGG: AI-2 transport system substrate-binding protein

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b2048	cpsG	phosphomannomutase (NCBI)	no	0.23
2	b0227	yafL	predicted lipoprotein and C40 family peptidase (NCBI)	0.47	0.21
3	b4500	yfaS	no description	no	0.21
4	b0577	ybdG	predicted mechanosensitive channel (NCBI)	no	0.20
5	b4300	sgcR	KpLE2 phage-like element; predicted DNA-binding transcriptional regulator (NCBI)	no	0.20
6	b1667	ydhR	hypothetical protein (NCBI)	no	0.19
7	b1560	ydfU	Qin prophage; predicted protein (RefSeq)	0.52	0.19
8	b4127	yjdJ	predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI)	no	0.19
9	b3421	rtcB	hypothetical protein (NCBI)	no	0.19
10	b4566	yjhX	hypothetical protein (NCBI)	0.51	0.19
11	b1521	uxaB	tagaturonate reductase (NCBI)	no	0.18
12	b1697	ydiQ	hypothetical protein (NCBI)	no	0.18
13	b2487	hyfG	hydrogenase 4, subunit (NCBI)	no	0.18
14	b2957	ansB	periplasmic L-asparaginase II (NCBI)	no	0.18
15	b0979	appB	cytochrome bd-II oxidase, subunit II (NCBI)	no	0.17
16	b2061	wzb	protein-tyrosine phosphatase (NCBI)	no	0.17
17	b1272	sohB	predicted inner membrane peptidase (NCBI)	0.27	0.17
18	b0219	yafV	predicted C-N hydrolase family amidase, NAD(P)-binding (NCBI)	no	0.17
19	b1390	paaC	predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI)	no	0.16
20	b1343	dbpA	ATP-dependent RNA helicase, specific for 23S rRNA (NCBI)	no	0.16

Or look for negative cofitness