Top cofit genes for b1489 from Escherichia coli BW25113

b1489: putative enzyme (VIMSS)
SEED: Heme-regulated cyclic AMP phosphodiesterase (EC 3.1.4.-)
KEGG: c-di-GMP-specific phosphodiesterase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1232	purU	formyltetrahydrofolate deformylase (NCBI)	no	0.44
2	b1285	gmr	modulator of Rnase II stability (NCBI)	no	0.42
3	b3773	ilvY	DNA-binding transcriptional dual regulator (NCBI)	no	0.41
4	b4013	metA	homoserine O-succinyltransferase (NCBI)	0.27	0.39
5	b3939	metB	cystathionine gamma-synthase (NCBI)	no	0.38
6	b3772	ilvA	threonine dehydratase (NCBI)	no	0.37
7	b3781	trxA	thioredoxin 1 (VIMSS)	no	0.37
8	b2603	yfiR	hypothetical protein (NCBI)	no	0.37
9	b2290	yfbQ	aspartate aminotransferase (NCBI)	no	0.37
10	b0242	proB	gamma-glutamyl kinase (NCBI)	no	0.37
11	b0243	proA	gamma-glutamyl phosphate reductase (NCBI)	no	0.36
12	b2479	gcvR	transcriptional regulation of gcv operon (VIMSS)	no	0.36
13	b2751	cysN	sulfate adenylyltransferase subunit 1 (NCBI)	no	0.36
14	b3008	metC	cystathionine beta-lyase (NCBI)	no	0.36
15	b4019	metH	B12-dependent methionine synthase (NCBI)	no	0.36
16	b2752	cysD	sulfate adenylyltransferase subunit 2 (NCBI)	no	0.35
17	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	no	0.35
18	b1262	trpC	N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS)	no	0.35
19	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	no	0.35
20	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	no	0.34

Or look for negative cofitness