Top cofit genes for b0945 from Escherichia coli BW25113

pyrD: dihydroorotate dehydrogenase (NCBI)
SEED: Dihydroorotate dehydrogenase (EC 1.3.3.1)
KEGG: dihydroorotate dehydrogenase (fumarate)

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1062	pyrC	dihydroorotase (NCBI)	0.98	0.97
2	b3642	pyrE	orotate phosphoribosyltransferase (NCBI)	0.98	0.95
3	b1281	pyrF	orotidine 5'-phosphate decarboxylase (NCBI)	0.99	0.94
4	b4245	pyrB	aspartate carbamoyltransferase catalytic subunit (NCBI)	0.98	0.94
5	b2557	purL	phosphoribosylformylglycinamidine synthase (NCBI)	0.98	0.91
6	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.98	0.91
7	b4006	purH	bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI)	0.98	0.91
8	b4005	purD	phosphoribosylamine--glycine ligase (NCBI)	0.97	0.91
9	b2499	purM	phosphoribosylaminoimidazole synthetase (NCBI)	0.98	0.90
10	b0523	purE	phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)	0.96	0.90
11	b0032	carA	carbamoyl-phosphate synthase small subunit (NCBI)	0.98	0.90
12	b2312	purF	amidophosphoribosyltransferase (NCBI)	0.97	0.90
13	b0522	purK	phosphoribosylaminoimidazole carboxylase (NCBI)	0.96	0.89
14	b2476	purC	phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)	0.96	0.88
15	b2023	hisH	imidazole glycerol phosphate synthase subunit HisH (NCBI)	0.95	0.83
16	b3389	aroB	3-dehydroquinate synthase (NCBI)	0.89	0.82
17	b3281	aroE	dehydroshikimate reductase, NAD(P)-binding (NCBI)	0.94	0.82
18	b0908	aroA	3-phosphoshikimate 1-carboxyvinyltransferase (NCBI)	0.93	0.81
19	b2329	aroC	chorismate synthase (NCBI)	0.91	0.81
20	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	0.57	0.81

Or look for negative cofitness