Top cofit genes for b0859 from Escherichia coli BW25113

rumB: 23S rRNA m(5)U747-methyltransferase (NCBI)
SEED: 23S rRNA (Uracil-5-) -methyltransferase rumB (EC 2.1.1.-)
KEGG: RNA methyltransferase, TrmA family

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4022	yjbC	23S rRNA pseudouridine synthase (NCBI)	no	0.44
2	b2806	ygdE	predicted methyltransferase (NCBI)	no	0.43
3	b1085	b1085	orf, hypothetical protein (VIMSS)	no	0.40
4	b3753	rbsR	DNA-binding transcriptional repressor of ribose metabolism (NCBI)	0.45	0.39
5	b4049	dusA	tRNA-dihydrouridine synthase A (RefSeq)	0.60	0.38
6	b3740	gidB	glucose-inhibited division protein B (NCBI)	0.33	0.38
7	b3929	rraA	ribonuclease activity regulator protein RraA (NCBI)	no	0.36
8	b2576	srmB	ATP-dependent RNA helicase (NCBI)	no	0.34
9	b3686	ibpB	heat shock chaperone (NCBI)	no	0.34
10	b2535	csiE	orf, hypothetical protein (VIMSS)	no	0.33
11	b1128	ycfD	orf, hypothetical protein (VIMSS)	0.38	0.33
12	b2317	dedA	conserved inner membrane protein (NCBI)	0.39	0.33
13	b3197	kdsD	D-arabinose 5-phosphate isomerase (NCBI)	no	0.33
14	b1725	yniA	predicted phosphotransferase/kinase (NCBI)	0.20	0.32
15	b3229	sspA	stringent starvation protein A (NCBI)	no	0.32
16	b2474	ypfI	predicted hydrolase (NCBI)	0.53	0.32
17	b3644	yicC	hypothetical protein (NCBI)	0.44	0.32
18	b4172	hfq	RNA-binding protein Hfq (NCBI)	no	0.31
19	b2464	talA	transaldolase A (NCBI)	no	0.31
20	b4371	rsmC	16S ribosomal RNA m2G1207 methyltransferase (NCBI)	0.61	0.31

Or look for negative cofitness