Top cofit genes for b0777 from Escherichia coli BW25113

bioC: predicted methltransferase, enzyme of biotin synthesis (NCBI)
SEED: Biotin synthesis protein BioC
KEGG: biotin synthesis protein BioC

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0775	bioB	biotin synthase (NCBI)	0.98	0.48
2	b0776	bioF	8-amino-7-oxononanoate synthase (NCBI)	0.98	0.47
3	b0774	bioA	adenosylmethionine--8-amino-7-oxononanoate transaminase (NCBI)	0.99	0.43
4	b0109	nadC	nicotinate-nucleotide pyrophosphorylase (NCBI)	0.83	0.43
5	b2574	nadB	L-aspartate oxidase (NCBI)	0.84	0.41
6	b4018	iclR	repressor of aceBA operon (VIMSS)	no	0.40
7	b2422	cysA	sulfate/thiosulfate transporter subunit (NCBI)	0.37	0.39
8	b0750	nadA	quinolinate synthetase (NCBI)	0.82	0.39
9	b0907	serC	phosphoserine aminotransferase (NCBI)	0.57	0.38
10	b0002	thrA	bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI)	0.45	0.38
11	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.60	0.37
12	b0032	carA	carbamoyl-phosphate synthase small subunit (NCBI)	0.61	0.37
13	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.41	0.36
14	b2751	cysN	sulfate adenylyltransferase subunit 1 (NCBI)	0.40	0.36
15	b0004	thrC	threonine synthase (NCBI)	0.65	0.36
16	b0003	thrB	homoserine kinase (NCBI)	0.47	0.36
17	b1260	trpA	tryptophan synthase subunit alpha (NCBI)	0.70	0.36
18	b2320	pdxB	erythronate-4-phosphate dehydrogenase (NCBI)	0.61	0.36
19	b0242	proB	gamma-glutamyl kinase (NCBI)	0.73	0.36
20	b2752	cysD	sulfate adenylyltransferase subunit 2 (NCBI)	0.56	0.36

Or look for negative cofitness