Top cofit genes for b0464 from Escherichia coli BW25113

acrR: DNA-binding transcriptional repressor (NCBI)
SEED: Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family
KEGG: TetR/AcrR family transcriptional regulator, acrAB operon repressor

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1530	marR	multiple antibiotic resistance protein; repressor of mar operon (VIMSS)	0.87	0.77
2	b0439	lon	DNA-binding ATP-dependent protease La (NCBI)	0.43	0.59
3	b1049	mdoH	glucosyltransferase MdoH (NCBI)	0.49	0.57
4	b1048	mdoG	glucan biosynthesis protein, periplasmic (NCBI)	0.27	0.56
5	b2570	rseC	RseC protein involved in reduction of the SoxR iron-sulfur cluster (NCBI)	no	0.52
6	b2214	yojL	predicted thiamine biosynthesis lipoprotein (NCBI)	0.21	0.50
7	b3546	yhjW	orf, hypothetical protein (VIMSS)	0.47	0.50
8	b3057	bacA	undecaprenyl pyrophosphate phosphatase (NCBI)	0.50	0.50
9	b1629	rsxC	electron transport complex protein RnfC (NCBI)	0.75	0.48
10	b2947	gshB	glutathione synthetase (NCBI)	0.74	0.48
11	b1632	rsxE	NADH-ubiquinone oxidoreductase (NCBI)	0.52	0.47
12	b3290	trkA	potassium transporter peripheral membrane component (NCBI)	0.21	0.45
13	b2684	mprA	DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI)	0.64	0.45
14	b3162	deaD	inducible ATP-independent RNA helicase (VIMSS)	no	0.41
15	b3204	ptsN	sugar-specific enzyme IIA component of PTS (NCBI)	no	0.41
16	b3205	yhbJ	hypothetical protein (NCBI)	0.62	0.41
17	b2912	ygfA	putative ligase (VIMSS)	0.46	0.41
18	b2688	gshA	glutamate--cysteine ligase (NCBI)	0.73	0.40
19	b2618	b2618	orf, hypothetical protein (VIMSS)	0.35	0.39
20	b1630	rsxD	electron transport complex protein RnfD (NCBI)	0.29	0.38

Or look for negative cofitness