Top cofit genes for b0386 from Escherichia coli BW25113

proC: pyrroline-5-carboxylate reductase (NCBI)
SEED: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
KEGG: pyrroline-5-carboxylate reductase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0243	proA	gamma-glutamyl phosphate reductase (NCBI)	0.99	0.90
2	b0242	proB	gamma-glutamyl kinase (NCBI)	0.99	0.90
3	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.94	0.88
4	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.98	0.88
5	b3389	aroB	3-dehydroquinate synthase (NCBI)	0.91	0.88
6	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.98	0.87
7	b3281	aroE	dehydroshikimate reductase, NAD(P)-binding (NCBI)	0.92	0.87
8	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.97	0.87
9	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.98	0.87
10	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.98	0.87
11	b3772	ilvA	threonine dehydratase (NCBI)	0.97	0.87
12	b0908	aroA	3-phosphoshikimate 1-carboxyvinyltransferase (NCBI)	0.92	0.87
13	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.97	0.87
14	b0073	leuB	3-isopropylmalate dehydrogenase (VIMSS)	0.98	0.87
15	b2020	hisD	histidinol dehydrogenase (NCBI)	0.98	0.86
16	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.96	0.86
17	b0071	leuD	isopropylmalate isomerase small subunit (NCBI)	0.97	0.86
18	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.98	0.86
19	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.97	0.86
20	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	no	0.85

Or look for negative cofitness