Top cofit genes for b0113 from Escherichia coli BW25113

pdhR: transcriptional regulator of pyruvate dehydrogenase complex (NCBI)
SEED: Transcriptional repressor for pyruvate dehydrogenase complex
KEGG: GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3772	ilvA	threonine dehydratase (NCBI)	0.67	0.80
2	b3368	cysG	fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI)	0.67	0.80
3	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.62	0.80
4	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.63	0.79
5	b2764	cysJ	sulfite reductase, alpha subunit, flavoprotein (NCBI)	0.61	0.79
6	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.66	0.79
7	b0073	leuB	3-isopropylmalate dehydrogenase (VIMSS)	0.64	0.79
8	b2763	cysI	sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI)	0.62	0.79
9	b0071	leuD	isopropylmalate isomerase small subunit (NCBI)	0.64	0.79
10	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.63	0.78
11	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.62	0.78
12	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.62	0.78
13	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	0.37	0.78
14	b2600	tyrA	fused chorismate mutase T/prephenate dehydrogenase (NCBI)	0.50	0.78
15	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.63	0.78
16	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.38	0.77
17	b3008	metC	cystathionine beta-lyase (NCBI)	0.67	0.77
18	b2020	hisD	histidinol dehydrogenase (NCBI)	0.52	0.77
19	b2750	cysC	adenylylsulfate kinase (NCBI)	0.67	0.77
20	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.55	0.77

Or look for negative cofitness