Top cofit genes for b0113 from Escherichia coli BW25113

pdhR: transcriptional regulator of pyruvate dehydrogenase complex (NCBI)
SEED: Transcriptional repressor for pyruvate dehydrogenase complex
KEGG: GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3772	ilvA	threonine dehydratase (NCBI)	0.67	0.81
2	b3368	cysG	fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI)	0.67	0.81
3	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.66	0.80
4	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.63	0.80
5	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.66	0.80
6	b2764	cysJ	sulfite reductase, alpha subunit, flavoprotein (NCBI)	0.61	0.80
7	b0073	leuB	3-isopropylmalate dehydrogenase (VIMSS)	0.64	0.80
8	b2763	cysI	sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI)	0.62	0.79
9	b0071	leuD	isopropylmalate isomerase small subunit (NCBI)	0.64	0.79
10	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.63	0.79
11	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.64	0.79
12	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.62	0.78
13	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	0.22	0.78
14	b2600	tyrA	fused chorismate mutase T/prephenate dehydrogenase (NCBI)	0.50	0.78
15	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.63	0.78
16	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.70	0.78
17	b3008	metC	cystathionine beta-lyase (NCBI)	0.67	0.78
18	b2020	hisD	histidinol dehydrogenase (NCBI)	0.66	0.77
19	b2750	cysC	adenylylsulfate kinase (NCBI)	0.67	0.77
20	b1262	trpC	N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS)	0.73	0.77

Or look for negative cofitness