Top cofit genes for b0109 from Escherichia coli BW25113

nadC: nicotinate-nucleotide pyrophosphorylase (NCBI)
SEED: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
KEGG: nicotinate-nucleotide pyrophosphorylase (carboxylating)

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0750	nadA	quinolinate synthetase (NCBI)	0.97	0.88
2	b2574	nadB	L-aspartate oxidase (NCBI)	0.99	0.87
3	b0052	pdxA	4-hydroxythreonine-4-phosphate dehydrogenase (NCBI)	0.86	0.68
4	b3828	metR	DNA-binding transcriptional activator, homocysteine-binding (NCBI)	0.85	0.68
5	b4214	cysQ	PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI)	0.95	0.68
6	b2320	pdxB	erythronate-4-phosphate dehydrogenase (NCBI)	0.74	0.67
7	b2020	hisD	histidinol dehydrogenase (NCBI)	0.87	0.67
8	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.87	0.67
9	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.85	0.66
10	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	0.85	0.66
11	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	no	0.66
12	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.87	0.65
13	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.88	0.65
14	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.88	0.65
15	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.87	0.65
16	b2600	tyrA	fused chorismate mutase T/prephenate dehydrogenase (NCBI)	0.83	0.65
17	b2751	cysN	sulfate adenylyltransferase subunit 1 (NCBI)	0.92	0.65
18	b2599	pheA	fused chorismate mutase P/prephenate dehydratase (NCBI)	0.88	0.65
19	b0242	proB	gamma-glutamyl kinase (NCBI)	0.89	0.65
20	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.87	0.65

Or look for negative cofitness