Top cofit genes for b0049 from Escherichia coli BW25113

apaH: diadenosinetetraphosphatase (NCBI)
SEED: Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)
KEGG: bis(5'-nucleosyl)-tetraphosphatase (symmetrical)

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	0.77	0.60
2	b3389	aroB	3-dehydroquinate synthase (NCBI)	0.79	0.60
3	b3281	aroE	dehydroshikimate reductase, NAD(P)-binding (NCBI)	0.75	0.59
4	b3828	metR	DNA-binding transcriptional activator, homocysteine-binding (NCBI)	0.67	0.58
5	b3650	spoT	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI)	0.86	0.58
6	b0386	proC	pyrroline-5-carboxylate reductase (NCBI)	0.69	0.57
7	b0908	aroA	3-phosphoshikimate 1-carboxyvinyltransferase (NCBI)	0.66	0.57
8	b3204	ptsN	sugar-specific enzyme IIA component of PTS (NCBI)	0.75	0.57
9	b4214	cysQ	PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI)	0.68	0.57
10	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.70	0.56
11	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.69	0.55
12	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.67	0.55
13	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.68	0.55
14	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.68	0.55
15	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.62	0.55
16	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.73	0.55
17	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.72	0.55
18	b2599	pheA	fused chorismate mutase P/prephenate dehydratase (NCBI)	0.56	0.55
19	b2020	hisD	histidinol dehydrogenase (NCBI)	0.69	0.55
20	b2029	gnd	6-phosphogluconate dehydrogenase (NCBI)	0.42	0.54

Or look for negative cofitness