Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2719c

Experiment: 7H9 with hypochlorite 0.4 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2717c and Rv2718c are separated by 51 nucleotidesRv2718c and Rv2719c are separated by 162 nucleotidesRv2719c and Rv2720 are separated by 250 nucleotidesRv2720 and Rv2721c are separated by 21 nucleotides Rv2717c: Rv2717c - Conserved protein, at 3,029,867 to 3,030,361 Rv2717c Rv2718c: Rv2718c - Probable transcriptional regulatory protein NrdR, at 3,030,413 to 3,030,877 Rv2718c Rv2719c: Rv2719c - Possible conserved membrane protein, at 3,031,040 to 3,031,537 Rv2719c Rv2720: Rv2720 - Repressor LexA, at 3,031,788 to 3,032,498 Rv2720 Rv2721c: Rv2721c - Possible conserved transmembrane alanine and glycine rich protein, at 3,032,520 to 3,034,619 Rv2721c Position (kb) 3031 3032Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3030.153 kb on + strand, within Rv2717cat 3030.210 kb on + strand, within Rv2717cat 3030.226 kb on + strand, within Rv2717cat 3030.227 kb on - strand, within Rv2717cat 3030.259 kb on - strand, within Rv2717cat 3030.283 kb on - strand, within Rv2717cat 3030.428 kb on + strandat 3030.428 kb on + strandat 3030.512 kb on + strand, within Rv2718cat 3030.512 kb on + strand, within Rv2718cat 3030.512 kb on + strand, within Rv2718cat 3030.513 kb on - strand, within Rv2718cat 3030.513 kb on - strand, within Rv2718cat 3030.517 kb on - strand, within Rv2718cat 3030.735 kb on - strand, within Rv2718cat 3030.929 kb on + strandat 3030.929 kb on + strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3030.930 kb on - strandat 3031.193 kb on + strand, within Rv2719cat 3031.300 kb on + strand, within Rv2719cat 3031.301 kb on - strand, within Rv2719cat 3031.398 kb on + strand, within Rv2719cat 3031.513 kb on + strandat 3031.775 kb on + strandat 3031.775 kb on + strandat 3031.775 kb on + strandat 3031.776 kb on - strandat 3032.531 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with hypochlorite 0.4 vol%
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3,030,153 + Rv2717c 0.58 -1.3
3,030,210 + Rv2717c 0.69 -1.9
3,030,226 + Rv2717c 0.73 -1.7
3,030,227 - Rv2717c 0.73 -0.7
3,030,259 - Rv2717c 0.79 +0.7
3,030,283 - Rv2717c 0.84 +0.7
3,030,428 + -0.3
3,030,428 + -0.2
3,030,512 + Rv2718c 0.21 -0.9
3,030,512 + Rv2718c 0.21 -0.9
3,030,512 + Rv2718c 0.21 -1.4
3,030,513 - Rv2718c 0.22 -0.7
3,030,513 - Rv2718c 0.22 -0.6
3,030,517 - Rv2718c 0.22 -0.2
3,030,735 - Rv2718c 0.69 -0.4
3,030,929 + +0.7
3,030,929 + -0.6
3,030,930 - -0.7
3,030,930 - -0.4
3,030,930 - -0.4
3,030,930 - +0.9
3,030,930 - -0.4
3,031,193 + Rv2719c 0.31 +2.8
3,031,300 + Rv2719c 0.52 -0.4
3,031,301 - Rv2719c 0.52 +1.9
3,031,398 + Rv2719c 0.72 -0.6
3,031,513 + -2.4
3,031,775 + +0.6
3,031,775 + -0.4
3,031,775 + +0.2
3,031,776 - +0.2
3,032,531 + +0.1

Or see this region's nucleotide sequence