Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3530c

Experiment: 7H9 with Geneticin G418 0.35 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3529c and Rv3530c overlap by 1 nucleotidesRv3530c and Rv3531c overlap by 4 nucleotides Rv3529c: Rv3529c - Conserved hypothetical protein, at 3,965,884 to 3,967,038 Rv3529c Rv3530c: Rv3530c - Possible oxidoreductase, at 3,967,038 to 3,967,820 Rv3530c Rv3531c: Rv3531c - Hypothetical protein, at 3,967,817 to 3,968,944 Rv3531c Position (kb) 3967 3968Strain fitness (log2 ratio) -2 -1 0 1 2at 3966.048 kb on + strand, within Rv3529cat 3966.049 kb on - strand, within Rv3529cat 3966.331 kb on + strand, within Rv3529cat 3966.479 kb on + strand, within Rv3529cat 3966.479 kb on + strand, within Rv3529cat 3966.479 kb on + strand, within Rv3529cat 3966.899 kb on + strand, within Rv3529cat 3967.459 kb on - strand, within Rv3530cat 3967.577 kb on - strand, within Rv3530cat 3967.609 kb on - strand, within Rv3530cat 3967.609 kb on - strand, within Rv3530cat 3967.902 kb on + strandat 3968.139 kb on + strand, within Rv3531cat 3968.154 kb on + strand, within Rv3531cat 3968.180 kb on + strand, within Rv3531cat 3968.180 kb on + strand, within Rv3531cat 3968.326 kb on - strand, within Rv3531cat 3968.345 kb on + strand, within Rv3531cat 3968.511 kb on - strand, within Rv3531cat 3968.511 kb on - strand, within Rv3531cat 3968.611 kb on + strand, within Rv3531cat 3968.612 kb on - strand, within Rv3531cat 3968.614 kb on - strand, within Rv3531cat 3968.685 kb on + strand, within Rv3531cat 3968.797 kb on - strand, within Rv3531c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Geneticin G418 0.35 mM
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3,966,048 + Rv3529c 0.14 +1.9
3,966,049 - Rv3529c 0.14 +0.0
3,966,331 + Rv3529c 0.39 -0.0
3,966,479 + Rv3529c 0.52 -1.2
3,966,479 + Rv3529c 0.52 +0.2
3,966,479 + Rv3529c 0.52 -0.6
3,966,899 + Rv3529c 0.88 -0.7
3,967,459 - Rv3530c 0.54 -1.7
3,967,577 - Rv3530c 0.69 -0.8
3,967,609 - Rv3530c 0.73 -0.1
3,967,609 - Rv3530c 0.73 -1.4
3,967,902 + +0.3
3,968,139 + Rv3531c 0.29 +0.1
3,968,154 + Rv3531c 0.30 -0.1
3,968,180 + Rv3531c 0.32 -1.1
3,968,180 + Rv3531c 0.32 +0.0
3,968,326 - Rv3531c 0.45 +0.1
3,968,345 + Rv3531c 0.47 -0.8
3,968,511 - Rv3531c 0.62 +0.5
3,968,511 - Rv3531c 0.62 -0.2
3,968,611 + Rv3531c 0.70 -2.2
3,968,612 - Rv3531c 0.70 -0.9
3,968,614 - Rv3531c 0.71 -0.8
3,968,685 + Rv3531c 0.77 +0.7
3,968,797 - Rv3531c 0.87 +1.4

Or see this region's nucleotide sequence