Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0052

Experiment: 7H9 with Sisomicin 0.07 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0051 and Rv0052 are separated by 31 nucleotidesRv0052 and Rv0053 are separated by 218 nucleotidesRv0053 and Rv0054 are separated by 103 nucleotides Rv0051: Rv0051 - Probable conserved transmembrane protein, at 55,696 to 57,378 Rv0051 Rv0052: Rv0052 - Conserved protein, at 57,410 to 57,973 Rv0052 Rv0053: Rv0053 - 30S ribosomal protein S6 RpsF, at 58,192 to 58,482 Rv0053 Rv0054: Rv0054 - Single-strand binding protein Ssb (helix-destabilizing protein), at 58,586 to 59,080 Rv0054 Position (kb) 57 58Strain fitness (log2 ratio) -2 -1 0 1 2 3at 56.521 kb on + strand, within Rv0051at 56.540 kb on - strand, within Rv0051at 57.046 kb on + strand, within Rv0051at 57.047 kb on - strand, within Rv0051at 57.050 kb on + strand, within Rv0051at 57.051 kb on - strand, within Rv0051at 57.052 kb on + strand, within Rv0051at 57.510 kb on + strand, within Rv0052at 57.510 kb on + strand, within Rv0052at 57.702 kb on + strand, within Rv0052at 57.879 kb on - strand, within Rv0052at 57.957 kb on - strandat 58.105 kb on + strandat 58.480 kb on + strandat 58.526 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Sisomicin 0.07 mM
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56,521 + Rv0051 0.49 +0.8
56,540 - Rv0051 0.50 +1.4
57,046 + Rv0051 0.80 +3.3
57,047 - Rv0051 0.80 +0.8
57,050 + Rv0051 0.80 -0.1
57,051 - Rv0051 0.81 +1.6
57,052 + Rv0051 0.81 +1.5
57,510 + Rv0052 0.18 -1.5
57,510 + Rv0052 0.18 -1.3
57,702 + Rv0052 0.52 -0.5
57,879 - Rv0052 0.83 -1.9
57,957 - -0.6
58,105 + +0.4
58,480 + +0.7
58,526 + -0.8

Or see this region's nucleotide sequence