Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0237

Experiment: 7H9 with Spectinomycin 0.029 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0236c and Rv0236A are separated by 46 nucleotidesRv0236A and Rv0237 are separated by 114 nucleotidesRv0237 and Rv0238 are separated by 75 nucleotidesRv0238 and Rv0239 are separated by 61 nucleotidesRv0239 and Rv0240 are separated by 7 nucleotides Rv0236c: Rv0236c - Possible arabinofuranosyltransferase AftD, at 282,649 to 286,851 Rv0236c Rv0236A: Rv0236A - Small secreted protein, at 286,898 to 287,071 Rv0236A Rv0237: Rv0237 - Probable conserved lipoprotein LpqI, at 287,186 to 288,352 Rv0237 Rv0238: Rv0238 - Possible transcriptional regulatory protein (probably TetR-family), at 288,428 to 289,042 Rv0238 Rv0239: Rv0239 - Possible antitoxin VapB24, at 289,104 to 289,337 Rv0239 Rv0240: Rv0240 - Possible toxin VapC24. Contains PIN domain., at 289,345 to 289,782 Rv0240 Position (kb) 287 288 289Strain fitness (log2 ratio) -2 -1 0 1 2 3at 287.159 kb on + strandat 287.160 kb on - strandat 287.211 kb on + strandat 287.212 kb on - strandat 287.441 kb on + strand, within Rv0237at 287.441 kb on + strand, within Rv0237at 287.442 kb on - strand, within Rv0237at 287.811 kb on - strand, within Rv0237at 287.811 kb on - strand, within Rv0237at 288.131 kb on - strand, within Rv0237at 288.131 kb on - strand, within Rv0237at 288.385 kb on - strandat 288.390 kb on + strandat 288.394 kb on + strandat 288.394 kb on + strandat 289.075 kb on + strandat 289.227 kb on + strand, within Rv0239

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Spectinomycin 0.029 mM
remove
287,159 + -0.1
287,160 - -0.9
287,211 + +0.3
287,212 - -0.3
287,441 + Rv0237 0.22 -1.3
287,441 + Rv0237 0.22 -2.4
287,442 - Rv0237 0.22 -1.8
287,811 - Rv0237 0.54 +0.1
287,811 - Rv0237 0.54 -0.3
288,131 - Rv0237 0.81 -1.0
288,131 - Rv0237 0.81 -1.3
288,385 - +0.2
288,390 + +3.2
288,394 + -1.0
288,394 + +0.8
289,075 + -0.7
289,227 + Rv0239 0.53 -0.7

Or see this region's nucleotide sequence