Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2892c

Experiment: 7H9 with Tetrazolium violet 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2890c and Rv2891 are separated by 283 nucleotidesRv2891 and Rv2892c overlap by 222 nucleotidesRv2892c and Rv2893 are separated by 399 nucleotides Rv2890c: Rv2890c - 30S ribosomal protein S2 RpsB, at 3,199,119 to 3,199,982 Rv2890c Rv2891: Rv2891 - Conserved hypothetical protein, at 3,200,266 to 3,201,015 Rv2891 Rv2892c: Rv2892c - PPE family protein PPE45, at 3,200,794 to 3,202,020 Rv2892c Rv2893: Rv2893 - Possible oxidoreductase, at 3,202,420 to 3,203,397 Rv2893 Position (kb) 3200 3201 3202 3203Strain fitness (log2 ratio) -2 -1 0 1 2at 3200.190 kb on - strandat 3200.190 kb on - strandat 3200.190 kb on - strandat 3200.304 kb on - strandat 3200.304 kb on - strandat 3200.304 kb on - strandat 3200.529 kb on - strand, within Rv2891at 3200.597 kb on - strand, within Rv2891at 3200.743 kb on + strand, within Rv2891at 3200.743 kb on + strand, within Rv2891at 3200.743 kb on + strand, within Rv2891at 3200.743 kb on + strand, within Rv2891at 3200.743 kb on + strand, within Rv2891at 3200.744 kb on - strand, within Rv2891at 3200.822 kb on - strandat 3200.840 kb on + strandat 3200.841 kb on - strandat 3200.841 kb on - strandat 3201.076 kb on + strand, within Rv2892cat 3201.076 kb on + strand, within Rv2892cat 3201.086 kb on + strand, within Rv2892cat 3201.087 kb on - strand, within Rv2892cat 3201.092 kb on + strand, within Rv2892cat 3201.092 kb on + strand, within Rv2892cat 3201.284 kb on + strand, within Rv2892cat 3201.501 kb on + strand, within Rv2892cat 3201.561 kb on - strand, within Rv2892cat 3201.561 kb on - strand, within Rv2892cat 3201.561 kb on - strand, within Rv2892cat 3201.561 kb on - strand, within Rv2892cat 3201.566 kb on + strand, within Rv2892cat 3201.566 kb on + strand, within Rv2892cat 3201.566 kb on + strand, within Rv2892cat 3201.566 kb on + strand, within Rv2892cat 3201.566 kb on + strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.567 kb on - strand, within Rv2892cat 3201.603 kb on - strand, within Rv2892cat 3201.806 kb on + strand, within Rv2892cat 3201.806 kb on + strand, within Rv2892cat 3201.807 kb on - strand, within Rv2892cat 3201.807 kb on - strand, within Rv2892cat 3201.855 kb on - strand, within Rv2892cat 3201.974 kb on + strandat 3201.974 kb on + strandat 3201.974 kb on + strandat 3201.975 kb on - strandat 3202.087 kb on + strandat 3202.087 kb on + strandat 3202.088 kb on - strandat 3202.198 kb on - strandat 3202.244 kb on + strandat 3202.446 kb on + strandat 3202.759 kb on + strand, within Rv2893at 3202.776 kb on + strand, within Rv2893at 3202.776 kb on + strand, within Rv2893at 3202.777 kb on - strand, within Rv2893

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Tetrazolium violet 0.065 mM
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3,200,190 - +2.0
3,200,190 - +0.7
3,200,190 - -0.1
3,200,304 - +0.3
3,200,304 - -0.2
3,200,304 - +1.4
3,200,529 - Rv2891 0.35 -1.3
3,200,597 - Rv2891 0.44 +0.2
3,200,743 + Rv2891 0.64 -0.4
3,200,743 + Rv2891 0.64 +0.6
3,200,743 + Rv2891 0.64 -0.1
3,200,743 + Rv2891 0.64 -0.2
3,200,743 + Rv2891 0.64 +0.4
3,200,744 - Rv2891 0.64 -0.3
3,200,822 - +0.0
3,200,840 + +0.7
3,200,841 - +0.7
3,200,841 - -0.1
3,201,076 + Rv2892c 0.23 -0.4
3,201,076 + Rv2892c 0.23 -0.4
3,201,086 + Rv2892c 0.24 +0.1
3,201,087 - Rv2892c 0.24 -0.5
3,201,092 + Rv2892c 0.24 +0.3
3,201,092 + Rv2892c 0.24 +0.4
3,201,284 + Rv2892c 0.40 -1.0
3,201,501 + Rv2892c 0.58 -0.1
3,201,561 - Rv2892c 0.63 +0.2
3,201,561 - Rv2892c 0.63 -0.2
3,201,561 - Rv2892c 0.63 -0.6
3,201,561 - Rv2892c 0.63 -0.5
3,201,566 + Rv2892c 0.63 -1.9
3,201,566 + Rv2892c 0.63 -1.8
3,201,566 + Rv2892c 0.63 -0.8
3,201,566 + Rv2892c 0.63 -0.1
3,201,566 + Rv2892c 0.63 -0.6
3,201,567 - Rv2892c 0.63 -0.0
3,201,567 - Rv2892c 0.63 +0.1
3,201,567 - Rv2892c 0.63 -0.9
3,201,567 - Rv2892c 0.63 -0.3
3,201,567 - Rv2892c 0.63 +1.0
3,201,567 - Rv2892c 0.63 +0.6
3,201,567 - Rv2892c 0.63 -0.1
3,201,567 - Rv2892c 0.63 -0.2
3,201,567 - Rv2892c 0.63 -0.2
3,201,603 - Rv2892c 0.66 -0.9
3,201,806 + Rv2892c 0.82 -0.5
3,201,806 + Rv2892c 0.82 -1.2
3,201,807 - Rv2892c 0.83 -2.0
3,201,807 - Rv2892c 0.83 -0.4
3,201,855 - Rv2892c 0.86 -0.4
3,201,974 + +0.9
3,201,974 + -2.2
3,201,974 + -0.6
3,201,975 - +0.0
3,202,087 + +0.3
3,202,087 + -0.4
3,202,088 - +0.3
3,202,198 - -0.1
3,202,244 + -0.7
3,202,446 + -0.7
3,202,759 + Rv2893 0.35 +0.0
3,202,776 + Rv2893 0.36 -1.7
3,202,776 + Rv2893 0.36 -1.0
3,202,777 - Rv2893 0.37 -1.3

Or see this region's nucleotide sequence