Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3542c

Experiment: 7H9 with Dibucaine 0.21 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3540c and Rv3541c overlap by 1 nucleotidesRv3541c and Rv3542c overlap by 4 nucleotidesRv3542c and Rv3543c overlap by 4 nucleotides Rv3540c: Rv3540c - Probable lipid transfer protein or keto acyl-CoA thiolase Ltp2, at 3,979,499 to 3,980,659 Rv3540c Rv3541c: Rv3541c - Conserved protein, at 3,980,659 to 3,981,048 Rv3541c Rv3542c: Rv3542c - Conserved hypothetical protein, at 3,981,045 to 3,981,980 Rv3542c Rv3543c: Rv3543c - Probable acyl-CoA dehydrogenase FadE29, at 3,981,977 to 3,983,140 Rv3543c Position (kb) 3981 3982Strain fitness (log2 ratio) -1 0 1 2at 3980.245 kb on - strand, within Rv3540cat 3980.795 kb on + strand, within Rv3541cat 3981.094 kb on + strandat 3981.113 kb on + strandat 3981.165 kb on + strand, within Rv3542cat 3981.280 kb on + strand, within Rv3542cat 3981.429 kb on - strand, within Rv3542cat 3981.649 kb on + strand, within Rv3542cat 3982.134 kb on + strand, within Rv3543cat 3982.377 kb on + strand, within Rv3543cat 3982.378 kb on - strand, within Rv3543cat 3982.506 kb on + strand, within Rv3543c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dibucaine 0.21 mM
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3,980,245 - Rv3540c 0.64 -0.2
3,980,795 + Rv3541c 0.35 +2.7
3,981,094 + +0.7
3,981,113 + -0.2
3,981,165 + Rv3542c 0.13 +1.9
3,981,280 + Rv3542c 0.25 -1.4
3,981,429 - Rv3542c 0.41 -1.1
3,981,649 + Rv3542c 0.65 +0.2
3,982,134 + Rv3543c 0.13 +0.1
3,982,377 + Rv3543c 0.34 +0.6
3,982,378 - Rv3543c 0.34 -0.6
3,982,506 + Rv3543c 0.45 +1.5

Or see this region's nucleotide sequence