Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2962c

Experiment: cholesterol 100uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2959c and Rv2960c are separated by 114 nucleotidesRv2960c and Rv2961 are separated by 81 nucleotidesRv2961 and Rv2962c are separated by 100 nucleotidesRv2962c and Rv2963 are separated by 113 nucleotides Rv2959c: Rv2959c - Possible methyltransferase (methylase), at 3,312,101 to 3,312,838 Rv2959c Rv2960c: Rv2960c - Hypothetical protein, at 3,312,953 to 3,313,201 Rv2960c Rv2961: Rv2961 - Probable transposase, at 3,313,283 to 3,313,672 Rv2961 Rv2962c: Rv2962c - Possible glycosyl transferase, at 3,313,773 to 3,315,122 Rv2962c Rv2963: Rv2963 - Probable integral membrane protein, at 3,315,236 to 3,316,456 Rv2963 Position (kb) 3313 3314 3315 3316Strain fitness (log2 ratio) -2 -1 0 1 2at 3312.901 kb on + strandat 3312.933 kb on + strandat 3312.933 kb on + strandat 3312.934 kb on - strandat 3313.020 kb on - strand, within Rv2960cat 3313.077 kb on + strand, within Rv2960cat 3313.077 kb on + strand, within Rv2960cat 3313.077 kb on + strand, within Rv2960cat 3313.077 kb on + strand, within Rv2960cat 3313.094 kb on + strand, within Rv2960cat 3313.170 kb on - strand, within Rv2960cat 3313.178 kb on + strandat 3313.179 kb on - strandat 3313.318 kb on - strandat 3313.431 kb on + strand, within Rv2961at 3313.432 kb on - strand, within Rv2961at 3313.436 kb on - strand, within Rv2961at 3313.770 kb on + strandat 3314.003 kb on + strand, within Rv2962cat 3314.137 kb on + strand, within Rv2962cat 3314.138 kb on - strand, within Rv2962cat 3314.138 kb on - strand, within Rv2962cat 3314.362 kb on + strand, within Rv2962cat 3314.386 kb on + strand, within Rv2962cat 3314.386 kb on + strand, within Rv2962cat 3314.587 kb on - strand, within Rv2962cat 3314.632 kb on + strand, within Rv2962cat 3314.654 kb on - strand, within Rv2962cat 3314.759 kb on - strand, within Rv2962cat 3314.782 kb on + strand, within Rv2962cat 3314.783 kb on - strand, within Rv2962cat 3314.866 kb on - strand, within Rv2962cat 3314.908 kb on + strand, within Rv2962cat 3315.103 kb on + strandat 3315.103 kb on + strandat 3315.104 kb on - strandat 3315.104 kb on - strandat 3315.157 kb on - strandat 3315.218 kb on + strandat 3315.438 kb on + strand, within Rv2963at 3315.439 kb on - strand, within Rv2963at 3315.480 kb on - strand, within Rv2963at 3315.508 kb on - strand, within Rv2963at 3315.508 kb on - strand, within Rv2963at 3315.991 kb on - strand, within Rv2963at 3316.110 kb on + strand, within Rv2963at 3316.111 kb on - strand, within Rv2963at 3316.111 kb on - strand, within Rv2963at 3316.111 kb on - strand, within Rv2963at 3316.116 kb on + strand, within Rv2963

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Per-strain Table

Position Strand Gene LocusTag Fraction cholesterol 100uM (C)
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3,312,901 + -0.5
3,312,933 + -0.6
3,312,933 + -0.4
3,312,934 - -1.7
3,313,020 - Rv2960c 0.27 +2.6
3,313,077 + Rv2960c 0.50 +2.0
3,313,077 + Rv2960c 0.50 +0.0
3,313,077 + Rv2960c 0.50 -0.3
3,313,077 + Rv2960c 0.50 +0.5
3,313,094 + Rv2960c 0.57 -0.6
3,313,170 - Rv2960c 0.87 -1.5
3,313,178 + +0.8
3,313,179 - +0.3
3,313,318 - -0.2
3,313,431 + Rv2961 0.38 -0.3
3,313,432 - Rv2961 0.38 -0.2
3,313,436 - Rv2961 0.39 -0.0
3,313,770 + -1.9
3,314,003 + Rv2962c 0.17 -0.8
3,314,137 + Rv2962c 0.27 +0.4
3,314,138 - Rv2962c 0.27 +1.5
3,314,138 - Rv2962c 0.27 -0.8
3,314,362 + Rv2962c 0.44 +0.5
3,314,386 + Rv2962c 0.45 -0.5
3,314,386 + Rv2962c 0.45 -0.2
3,314,587 - Rv2962c 0.60 -0.4
3,314,632 + Rv2962c 0.64 +1.3
3,314,654 - Rv2962c 0.65 -0.1
3,314,759 - Rv2962c 0.73 -0.3
3,314,782 + Rv2962c 0.75 +0.3
3,314,783 - Rv2962c 0.75 -0.3
3,314,866 - Rv2962c 0.81 +0.2
3,314,908 + Rv2962c 0.84 +0.8
3,315,103 + -0.3
3,315,103 + -0.2
3,315,104 - +1.0
3,315,104 - -0.4
3,315,157 - -1.3
3,315,218 + -0.2
3,315,438 + Rv2963 0.17 -0.5
3,315,439 - Rv2963 0.17 +0.1
3,315,480 - Rv2963 0.20 -0.0
3,315,508 - Rv2963 0.22 +1.1
3,315,508 - Rv2963 0.22 +0.3
3,315,991 - Rv2963 0.62 +0.4
3,316,110 + Rv2963 0.72 +1.4
3,316,111 - Rv2963 0.72 -0.3
3,316,111 - Rv2963 0.72 +0.0
3,316,111 - Rv2963 0.72 -0.6
3,316,116 + Rv2963 0.72 -0.4

Or see this region's nucleotide sequence