Experiment: NLDM_defined_nocarbon with D-Glucose and L-Methionine 1 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt yerC and hisG overlap by 4 nucleotides hisG and hisD are separated by 28 nucleotides hisD and hisC overlap by 4 nucleotides
OKGIIK_04940: yerC - TrpR , YerC/YecD, at 1,072,999 to 1,073,334
yerC
OKGIIK_04945: hisG - ATP phosphoribosyltransferase, at 1,073,331 to 1,074,224
hisG
OKGIIK_04950: hisD - histidinol dehydrogenase, at 1,074,253 to 1,075,551
hisD
OKGIIK_04955: hisC - histidinol-phosphate transaminase, at 1,075,548 to 1,076,639
hisC
Position (kb)
1074
1075
1076 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1
2
3
4 at 1073.272 kb on + strand, within yerC at 1073.272 kb on + strand, within yerC at 1073.273 kb on - strand, within yerC at 1073.671 kb on - strand, within hisG at 1073.671 kb on - strand, within hisG at 1073.671 kb on - strand, within hisG at 1073.716 kb on - strand, within hisG at 1073.716 kb on - strand, within hisG at 1073.849 kb on + strand, within hisG at 1074.415 kb on + strand, within hisD at 1074.415 kb on + strand, within hisD at 1074.415 kb on + strand, within hisD at 1074.415 kb on + strand, within hisD at 1074.415 kb on + strand, within hisD at 1074.533 kb on + strand, within hisD at 1074.533 kb on + strand, within hisD at 1074.533 kb on + strand, within hisD at 1074.534 kb on - strand, within hisD at 1074.534 kb on - strand, within hisD at 1074.534 kb on - strand, within hisD at 1074.534 kb on - strand, within hisD at 1074.534 kb on - strand, within hisD at 1074.534 kb on - strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.631 kb on + strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.632 kb on - strand, within hisD at 1074.766 kb on + strand, within hisD at 1074.766 kb on + strand, within hisD at 1074.766 kb on + strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.767 kb on - strand, within hisD at 1074.838 kb on + strand, within hisD at 1074.839 kb on - strand, within hisD at 1074.839 kb on - strand, within hisD at 1074.839 kb on - strand, within hisD at 1074.839 kb on - strand, within hisD at 1075.336 kb on + strand, within hisD at 1075.336 kb on + strand, within hisD at 1075.336 kb on + strand, within hisD at 1075.336 kb on + strand, within hisD at 1075.337 kb on - strand, within hisD at 1075.337 kb on - strand, within hisD at 1075.369 kb on + strand, within hisD at 1075.369 kb on + strand, within hisD at 1075.369 kb on + strand, within hisD at 1075.369 kb on + strand, within hisD at 1075.369 kb on + strand, within hisD at 1075.369 kb on + strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.370 kb on - strand, within hisD at 1075.376 kb on - strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.387 kb on + strand, within hisD at 1075.388 kb on - strand, within hisD at 1075.388 kb on - strand, within hisD at 1075.388 kb on - strand, within hisD at 1075.388 kb on - strand, within hisD at 1075.388 kb on - strand, within hisD at 1075.411 kb on + strand, within hisD at 1075.411 kb on + strand, within hisD at 1075.412 kb on - strand, within hisD at 1075.412 kb on - strand, within hisD at 1075.412 kb on - strand, within hisD at 1075.462 kb on - strand at 1075.596 kb on + strand at 1075.596 kb on + strand at 1075.596 kb on + strand at 1075.597 kb on - strand at 1075.597 kb on - strand at 1075.597 kb on - strand at 1075.597 kb on - strand at 1075.597 kb on - strand at 1075.597 kb on - strand at 1075.746 kb on + strand, within hisC at 1075.746 kb on + strand, within hisC at 1075.746 kb on + strand, within hisC at 1075.746 kb on + strand, within hisC at 1075.747 kb on - strand, within hisC at 1075.747 kb on - strand, within hisC at 1075.747 kb on - strand, within hisC at 1075.843 kb on + strand, within hisC at 1075.843 kb on + strand, within hisC at 1075.844 kb on - strand, within hisC at 1075.844 kb on - strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.872 kb on + strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1075.873 kb on - strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.097 kb on + strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.098 kb on - strand, within hisC at 1076.204 kb on + strand, within hisC at 1076.443 kb on + strand, within hisC at 1076.443 kb on + strand, within hisC at 1076.444 kb on - strand, within hisC at 1076.444 kb on - strand, within hisC at 1076.444 kb on - strand, within hisC at 1076.444 kb on - strand, within hisC
Per-strain Table
Position Strand Gene LocusTag Fraction NLDM_defined_nocarbon with D-Glucose and L-Methionine 1 mM remove 1,073,272 + yerC OKGIIK_04940 0.81 +4.0 1,073,272 + yerC OKGIIK_04940 0.81 +2.5 1,073,273 - yerC OKGIIK_04940 0.82 -2.9 1,073,671 - hisG OKGIIK_04945 0.38 -0.8 1,073,671 - hisG OKGIIK_04945 0.38 -1.8 1,073,671 - hisG OKGIIK_04945 0.38 -1.5 1,073,716 - hisG OKGIIK_04945 0.43 -0.8 1,073,716 - hisG OKGIIK_04945 0.43 -0.8 1,073,849 + hisG OKGIIK_04945 0.58 -0.8 1,074,415 + hisD OKGIIK_04950 0.12 -2.2 1,074,415 + hisD OKGIIK_04950 0.12 -2.6 1,074,415 + hisD OKGIIK_04950 0.12 -0.4 1,074,415 + hisD OKGIIK_04950 0.12 +0.8 1,074,415 + hisD OKGIIK_04950 0.12 -2.8 1,074,533 + hisD OKGIIK_04950 0.22 -1.8 1,074,533 + hisD OKGIIK_04950 0.22 -3.5 1,074,533 + hisD OKGIIK_04950 0.22 -1.5 1,074,534 - hisD OKGIIK_04950 0.22 -1.8 1,074,534 - hisD OKGIIK_04950 0.22 -2.3 1,074,534 - hisD OKGIIK_04950 0.22 -1.2 1,074,534 - hisD OKGIIK_04950 0.22 -3.1 1,074,534 - hisD OKGIIK_04950 0.22 -2.9 1,074,534 - hisD OKGIIK_04950 0.22 -2.5 1,074,631 + hisD OKGIIK_04950 0.29 -1.5 1,074,631 + hisD OKGIIK_04950 0.29 -4.2 1,074,631 + hisD OKGIIK_04950 0.29 -0.8 1,074,631 + hisD OKGIIK_04950 0.29 -3.0 1,074,631 + hisD OKGIIK_04950 0.29 -0.8 1,074,631 + hisD OKGIIK_04950 0.29 -2.2 1,074,631 + hisD OKGIIK_04950 0.29 +0.0 1,074,631 + hisD OKGIIK_04950 0.29 -2.6 1,074,631 + hisD OKGIIK_04950 0.29 -1.5 1,074,631 + hisD OKGIIK_04950 0.29 -1.2 1,074,631 + hisD OKGIIK_04950 0.29 -2.6 1,074,631 + hisD OKGIIK_04950 0.29 -1.2 1,074,631 + hisD OKGIIK_04950 0.29 -2.3 1,074,632 - hisD OKGIIK_04950 0.29 -1.5 1,074,632 - hisD OKGIIK_04950 0.29 -1.8 1,074,632 - hisD OKGIIK_04950 0.29 -2.8 1,074,632 - hisD OKGIIK_04950 0.29 -0.2 1,074,632 - hisD OKGIIK_04950 0.29 -1.5 1,074,632 - hisD OKGIIK_04950 0.29 -0.8 1,074,632 - hisD OKGIIK_04950 0.29 -2.0 1,074,632 - hisD OKGIIK_04950 0.29 -0.2 1,074,632 - hisD OKGIIK_04950 0.29 -3.3 1,074,632 - hisD OKGIIK_04950 0.29 -1.2 1,074,632 - hisD OKGIIK_04950 0.29 -1.5 1,074,632 - hisD OKGIIK_04950 0.29 -1.8 1,074,766 + hisD OKGIIK_04950 0.39 -2.6 1,074,766 + hisD OKGIIK_04950 0.39 -2.3 1,074,766 + hisD OKGIIK_04950 0.39 -1.5 1,074,767 - hisD OKGIIK_04950 0.40 -1.8 1,074,767 - hisD OKGIIK_04950 0.40 -3.2 1,074,767 - hisD OKGIIK_04950 0.40 -0.8 1,074,767 - hisD OKGIIK_04950 0.40 -3.1 1,074,767 - hisD OKGIIK_04950 0.40 -0.2 1,074,767 - hisD OKGIIK_04950 0.40 -3.0 1,074,767 - hisD OKGIIK_04950 0.40 +0.2 1,074,767 - hisD OKGIIK_04950 0.40 -2.2 1,074,838 + hisD OKGIIK_04950 0.45 -3.3 1,074,839 - hisD OKGIIK_04950 0.45 -2.2 1,074,839 - hisD OKGIIK_04950 0.45 -1.2 1,074,839 - hisD OKGIIK_04950 0.45 -1.5 1,074,839 - hisD OKGIIK_04950 0.45 -2.8 1,075,336 + hisD OKGIIK_04950 0.83 -2.3 1,075,336 + hisD OKGIIK_04950 0.83 -0.9 1,075,336 + hisD OKGIIK_04950 0.83 -1.2 1,075,336 + hisD OKGIIK_04950 0.83 -0.3 1,075,337 - hisD OKGIIK_04950 0.83 -2.3 1,075,337 - hisD OKGIIK_04950 0.83 -1.6 1,075,369 + hisD OKGIIK_04950 0.86 -1.8 1,075,369 + hisD OKGIIK_04950 0.86 -1.5 1,075,369 + hisD OKGIIK_04950 0.86 -1.8 1,075,369 + hisD OKGIIK_04950 0.86 +0.5 1,075,369 + hisD OKGIIK_04950 0.86 -1.8 1,075,369 + hisD OKGIIK_04950 0.86 -2.5 1,075,370 - hisD OKGIIK_04950 0.86 -0.4 1,075,370 - hisD OKGIIK_04950 0.86 +0.8 1,075,370 - hisD OKGIIK_04950 0.86 -0.8 1,075,370 - hisD OKGIIK_04950 0.86 -3.5 1,075,370 - hisD OKGIIK_04950 0.86 -3.0 1,075,370 - hisD OKGIIK_04950 0.86 -2.8 1,075,370 - hisD OKGIIK_04950 0.86 -2.3 1,075,370 - hisD OKGIIK_04950 0.86 -0.8 1,075,370 - hisD OKGIIK_04950 0.86 -2.6 1,075,370 - hisD OKGIIK_04950 0.86 -1.5 1,075,370 - hisD OKGIIK_04950 0.86 -0.8 1,075,370 - hisD OKGIIK_04950 0.86 -3.3 1,075,370 - hisD OKGIIK_04950 0.86 -4.1 1,075,370 - hisD OKGIIK_04950 0.86 -2.0 1,075,376 - hisD OKGIIK_04950 0.86 -1.2 1,075,387 + hisD OKGIIK_04950 0.87 -3.7 1,075,387 + hisD OKGIIK_04950 0.87 -0.8 1,075,387 + hisD OKGIIK_04950 0.87 -0.9 1,075,387 + hisD OKGIIK_04950 0.87 -1.5 1,075,387 + hisD OKGIIK_04950 0.87 -1.5 1,075,387 + hisD OKGIIK_04950 0.87 -0.8 1,075,387 + hisD OKGIIK_04950 0.87 -3.2 1,075,387 + hisD OKGIIK_04950 0.87 -3.6 1,075,388 - hisD OKGIIK_04950 0.87 -1.5 1,075,388 - hisD OKGIIK_04950 0.87 -0.2 1,075,388 - hisD OKGIIK_04950 0.87 -2.2 1,075,388 - hisD OKGIIK_04950 0.87 -1.5 1,075,388 - hisD OKGIIK_04950 0.87 -2.6 1,075,411 + hisD OKGIIK_04950 0.89 -2.2 1,075,411 + hisD OKGIIK_04950 0.89 -3.5 1,075,412 - hisD OKGIIK_04950 0.89 -3.1 1,075,412 - hisD OKGIIK_04950 0.89 -3.1 1,075,412 - hisD OKGIIK_04950 0.89 -3.0 1,075,462 - +0.8 1,075,596 + -3.8 1,075,596 + -1.5 1,075,596 + -1.2 1,075,597 - -3.3 1,075,597 - -2.5 1,075,597 - -0.8 1,075,597 - -2.3 1,075,597 - +0.8 1,075,597 - -1.8 1,075,746 + hisC OKGIIK_04955 0.18 -1.2 1,075,746 + hisC OKGIIK_04955 0.18 -2.2 1,075,746 + hisC OKGIIK_04955 0.18 -3.2 1,075,746 + hisC OKGIIK_04955 0.18 -1.8 1,075,747 - hisC OKGIIK_04955 0.18 -2.6 1,075,747 - hisC OKGIIK_04955 0.18 -1.5 1,075,747 - hisC OKGIIK_04955 0.18 -3.3 1,075,843 + hisC OKGIIK_04955 0.27 -4.6 1,075,843 + hisC OKGIIK_04955 0.27 -2.6 1,075,844 - hisC OKGIIK_04955 0.27 -4.8 1,075,844 - hisC OKGIIK_04955 0.27 -2.6 1,075,872 + hisC OKGIIK_04955 0.30 -1.5 1,075,872 + hisC OKGIIK_04955 0.30 -0.8 1,075,872 + hisC OKGIIK_04955 0.30 -2.3 1,075,872 + hisC OKGIIK_04955 0.30 -1.5 1,075,872 + hisC OKGIIK_04955 0.30 -2.3 1,075,872 + hisC OKGIIK_04955 0.30 -1.2 1,075,872 + hisC OKGIIK_04955 0.30 -3.3 1,075,872 + hisC OKGIIK_04955 0.30 -2.9 1,075,872 + hisC OKGIIK_04955 0.30 -3.3 1,075,872 + hisC OKGIIK_04955 0.30 -0.8 1,075,872 + hisC OKGIIK_04955 0.30 -2.0 1,075,872 + hisC OKGIIK_04955 0.30 -0.8 1,075,872 + hisC OKGIIK_04955 0.30 -4.5 1,075,872 + hisC OKGIIK_04955 0.30 -2.8 1,075,872 + hisC OKGIIK_04955 0.30 -1.2 1,075,872 + hisC OKGIIK_04955 0.30 -1.5 1,075,872 + hisC OKGIIK_04955 0.30 -2.8 1,075,872 + hisC OKGIIK_04955 0.30 -0.2 1,075,872 + hisC OKGIIK_04955 0.30 -2.5 1,075,873 - hisC OKGIIK_04955 0.30 -1.2 1,075,873 - hisC OKGIIK_04955 0.30 -3.6 1,075,873 - hisC OKGIIK_04955 0.30 -2.0 1,075,873 - hisC OKGIIK_04955 0.30 -2.2 1,075,873 - hisC OKGIIK_04955 0.30 -1.2 1,075,873 - hisC OKGIIK_04955 0.30 -0.2 1,075,873 - hisC OKGIIK_04955 0.30 -1.2 1,075,873 - hisC OKGIIK_04955 0.30 -1.8 1,075,873 - hisC OKGIIK_04955 0.30 -0.2 1,075,873 - hisC OKGIIK_04955 0.30 -2.3 1,075,873 - hisC OKGIIK_04955 0.30 -2.0 1,075,873 - hisC OKGIIK_04955 0.30 -1.8 1,075,873 - hisC OKGIIK_04955 0.30 -2.0 1,075,873 - hisC OKGIIK_04955 0.30 -2.8 1,076,097 + hisC OKGIIK_04955 0.50 -1.8 1,076,097 + hisC OKGIIK_04955 0.50 -2.2 1,076,097 + hisC OKGIIK_04955 0.50 -1.5 1,076,097 + hisC OKGIIK_04955 0.50 -0.8 1,076,097 + hisC OKGIIK_04955 0.50 -0.8 1,076,097 + hisC OKGIIK_04955 0.50 -2.3 1,076,097 + hisC OKGIIK_04955 0.50 -4.5 1,076,097 + hisC OKGIIK_04955 0.50 -3.0 1,076,097 + hisC OKGIIK_04955 0.50 -1.8 1,076,097 + hisC OKGIIK_04955 0.50 -2.0 1,076,097 + hisC OKGIIK_04955 0.50 -3.8 1,076,097 + hisC OKGIIK_04955 0.50 -0.8 1,076,097 + hisC OKGIIK_04955 0.50 -2.3 1,076,097 + hisC OKGIIK_04955 0.50 -2.5 1,076,097 + hisC OKGIIK_04955 0.50 -3.0 1,076,097 + hisC OKGIIK_04955 0.50 -1.2 1,076,097 + hisC OKGIIK_04955 0.50 -2.0 1,076,097 + hisC OKGIIK_04955 0.50 -3.3 1,076,097 + hisC OKGIIK_04955 0.50 -2.3 1,076,097 + hisC OKGIIK_04955 0.50 -2.6 1,076,097 + hisC OKGIIK_04955 0.50 -1.5 1,076,097 + hisC OKGIIK_04955 0.50 -0.2 1,076,098 - hisC OKGIIK_04955 0.50 +0.8 1,076,098 - hisC OKGIIK_04955 0.50 -2.6 1,076,098 - hisC OKGIIK_04955 0.50 -3.0 1,076,098 - hisC OKGIIK_04955 0.50 -2.0 1,076,098 - hisC OKGIIK_04955 0.50 -3.1 1,076,098 - hisC OKGIIK_04955 0.50 -3.2 1,076,098 - hisC OKGIIK_04955 0.50 -2.0 1,076,098 - hisC OKGIIK_04955 0.50 -3.7 1,076,098 - hisC OKGIIK_04955 0.50 +0.8 1,076,098 - hisC OKGIIK_04955 0.50 -1.5 1,076,098 - hisC OKGIIK_04955 0.50 -2.3 1,076,204 + hisC OKGIIK_04955 0.60 -1.5 1,076,443 + hisC OKGIIK_04955 0.82 -1.5 1,076,443 + hisC OKGIIK_04955 0.82 -2.2 1,076,444 - hisC OKGIIK_04955 0.82 -1.6 1,076,444 - hisC OKGIIK_04955 0.82 -2.8 1,076,444 - hisC OKGIIK_04955 0.82 -1.8 1,076,444 - hisC OKGIIK_04955 0.82 -2.3
Or see this region's nucleotide sequence