Experiment: Vancomycin 0.25 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4512 and PfGW456L13_4513 are separated by 76 nucleotides PfGW456L13_4513 and PfGW456L13_4514 are separated by 178 nucleotides
PfGW456L13_4512 - Exported zinc metalloprotease YfgC precursor, at 5,044,075 to 5,045,508
_4512
PfGW456L13_4513 - HtrA protease/chaperone protein, at 5,045,585 to 5,047,009
_4513
PfGW456L13_4514 - Sigma factor RpoE negative regulatory protein RseB precursor, at 5,047,188 to 5,048,147
_4514
Position (kb)
5045
5046
5047
5048 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 5044.699 kb on + strand, within PfGW456L13_4512 at 5044.754 kb on - strand, within PfGW456L13_4512 at 5044.892 kb on + strand, within PfGW456L13_4512 at 5044.903 kb on + strand, within PfGW456L13_4512 at 5044.904 kb on - strand, within PfGW456L13_4512 at 5044.904 kb on - strand, within PfGW456L13_4512 at 5045.077 kb on + strand, within PfGW456L13_4512 at 5045.077 kb on + strand, within PfGW456L13_4512 at 5045.078 kb on - strand, within PfGW456L13_4512 at 5045.078 kb on - strand, within PfGW456L13_4512 at 5045.078 kb on - strand, within PfGW456L13_4512 at 5045.113 kb on - strand, within PfGW456L13_4512 at 5045.161 kb on + strand, within PfGW456L13_4512 at 5045.161 kb on + strand, within PfGW456L13_4512 at 5045.162 kb on - strand, within PfGW456L13_4512 at 5045.174 kb on - strand, within PfGW456L13_4512 at 5045.174 kb on - strand, within PfGW456L13_4512 at 5045.287 kb on + strand, within PfGW456L13_4512 at 5045.322 kb on + strand, within PfGW456L13_4512 at 5045.322 kb on + strand, within PfGW456L13_4512 at 5045.323 kb on - strand, within PfGW456L13_4512 at 5045.353 kb on + strand, within PfGW456L13_4512 at 5045.353 kb on + strand, within PfGW456L13_4512 at 5045.375 kb on - strand at 5045.775 kb on - strand, within PfGW456L13_4513 at 5045.775 kb on - strand, within PfGW456L13_4513 at 5045.775 kb on - strand, within PfGW456L13_4513 at 5047.070 kb on - strand at 5047.245 kb on - strand at 5047.254 kb on + strand at 5047.338 kb on - strand, within PfGW456L13_4514 at 5047.408 kb on + strand, within PfGW456L13_4514 at 5047.408 kb on + strand, within PfGW456L13_4514 at 5047.408 kb on + strand, within PfGW456L13_4514 at 5047.408 kb on + strand, within PfGW456L13_4514 at 5047.408 kb on + strand, within PfGW456L13_4514 at 5047.409 kb on - strand, within PfGW456L13_4514 at 5047.409 kb on - strand, within PfGW456L13_4514 at 5047.409 kb on - strand, within PfGW456L13_4514 at 5047.409 kb on - strand, within PfGW456L13_4514 at 5047.409 kb on - strand, within PfGW456L13_4514 at 5047.418 kb on + strand, within PfGW456L13_4514 at 5047.565 kb on + strand, within PfGW456L13_4514 at 5047.566 kb on - strand, within PfGW456L13_4514 at 5047.796 kb on - strand, within PfGW456L13_4514 at 5047.982 kb on + strand, within PfGW456L13_4514 at 5047.983 kb on - strand, within PfGW456L13_4514 at 5047.998 kb on - strand, within PfGW456L13_4514 at 5048.003 kb on + strand, within PfGW456L13_4514
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.25 mg/ml remove 5,044,699 + PfGW456L13_4512 0.44 -3.9 5,044,754 - PfGW456L13_4512 0.47 +1.2 5,044,892 + PfGW456L13_4512 0.57 -1.4 5,044,903 + PfGW456L13_4512 0.58 -1.4 5,044,904 - PfGW456L13_4512 0.58 -0.6 5,044,904 - PfGW456L13_4512 0.58 -0.4 5,045,077 + PfGW456L13_4512 0.70 -1.8 5,045,077 + PfGW456L13_4512 0.70 -0.4 5,045,078 - PfGW456L13_4512 0.70 -0.2 5,045,078 - PfGW456L13_4512 0.70 +0.6 5,045,078 - PfGW456L13_4512 0.70 -1.0 5,045,113 - PfGW456L13_4512 0.72 +0.6 5,045,161 + PfGW456L13_4512 0.76 +0.4 5,045,161 + PfGW456L13_4512 0.76 -0.7 5,045,162 - PfGW456L13_4512 0.76 -0.0 5,045,174 - PfGW456L13_4512 0.77 -0.6 5,045,174 - PfGW456L13_4512 0.77 -0.5 5,045,287 + PfGW456L13_4512 0.85 +1.3 5,045,322 + PfGW456L13_4512 0.87 -1.7 5,045,322 + PfGW456L13_4512 0.87 +0.3 5,045,323 - PfGW456L13_4512 0.87 -1.4 5,045,353 + PfGW456L13_4512 0.89 -0.3 5,045,353 + PfGW456L13_4512 0.89 -1.4 5,045,375 - -0.6 5,045,775 - PfGW456L13_4513 0.13 -0.9 5,045,775 - PfGW456L13_4513 0.13 -0.0 5,045,775 - PfGW456L13_4513 0.13 -0.0 5,047,070 - -0.3 5,047,245 - -0.7 5,047,254 + +0.6 5,047,338 - PfGW456L13_4514 0.16 -0.2 5,047,408 + PfGW456L13_4514 0.23 -1.8 5,047,408 + PfGW456L13_4514 0.23 +0.5 5,047,408 + PfGW456L13_4514 0.23 +0.4 5,047,408 + PfGW456L13_4514 0.23 +0.5 5,047,408 + PfGW456L13_4514 0.23 -1.9 5,047,409 - PfGW456L13_4514 0.23 -0.0 5,047,409 - PfGW456L13_4514 0.23 +1.2 5,047,409 - PfGW456L13_4514 0.23 -1.0 5,047,409 - PfGW456L13_4514 0.23 +0.5 5,047,409 - PfGW456L13_4514 0.23 -0.0 5,047,418 + PfGW456L13_4514 0.24 -1.6 5,047,565 + PfGW456L13_4514 0.39 -1.7 5,047,566 - PfGW456L13_4514 0.39 -0.2 5,047,796 - PfGW456L13_4514 0.63 +1.5 5,047,982 + PfGW456L13_4514 0.83 -0.3 5,047,983 - PfGW456L13_4514 0.83 -0.3 5,047,998 - PfGW456L13_4514 0.84 +0.2 5,048,003 + PfGW456L13_4514 0.85 +1.8
Or see this region's nucleotide sequence