Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0591

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0590 and Rv0590A overlap by 52 nucleotidesRv0590A and Rv0591 overlap by 4 nucleotidesRv0591 and Rv0592 overlap by 4 nucleotides Rv0590: Rv0590 - Mce-family protein Mce2B, at 688,032 to 688,859 Rv0590 Rv0590A: Rv0590A - Mce-family related protein, at 688,808 to 689,062 Rv0590A Rv0591: Rv0591 - Mce-family protein Mce2C, at 689,059 to 690,504 Rv0591 Rv0592: Rv0592 - Mce-family protein Mce2D, at 690,501 to 692,027 Rv0592 Position (kb) 689 690 691Strain fitness (log2 ratio) -1 0 1 2at 688.235 kb on - strand, within Rv0590at 688.235 kb on - strand, within Rv0590at 688.937 kb on + strand, within Rv0590Aat 688.938 kb on - strand, within Rv0590Aat 689.011 kb on - strand, within Rv0590Aat 689.178 kb on + strandat 689.183 kb on - strandat 689.183 kb on - strandat 689.448 kb on + strand, within Rv0591at 690.413 kb on + strandat 690.413 kb on + strandat 690.413 kb on + strandat 690.493 kb on - strandat 690.493 kb on - strandat 690.654 kb on + strand, within Rv0592at 690.772 kb on - strand, within Rv0592at 690.865 kb on - strand, within Rv0592at 691.153 kb on + strand, within Rv0592at 691.364 kb on + strand, within Rv0592at 691.365 kb on - strand, within Rv0592at 691.449 kb on + strand, within Rv0592

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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688,235 - Rv0590 0.25 -0.0
688,235 - Rv0590 0.25 -0.2
688,937 + Rv0590A 0.51 -0.4
688,938 - Rv0590A 0.51 +0.3
689,011 - Rv0590A 0.80 -0.3
689,178 + -0.1
689,183 - -0.3
689,183 - -0.2
689,448 + Rv0591 0.27 -0.8
690,413 + -0.4
690,413 + -0.3
690,413 + -1.0
690,493 - +0.4
690,493 - -0.2
690,654 + Rv0592 0.10 +0.6
690,772 - Rv0592 0.18 -0.2
690,865 - Rv0592 0.24 +0.0
691,153 + Rv0592 0.43 +2.7
691,364 + Rv0592 0.57 +0.3
691,365 - Rv0592 0.57 +0.1
691,449 + Rv0592 0.62 -0.0

Or see this region's nucleotide sequence