Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_1774 and Pf1N1B4_1775 overlap by 4 nucleotides Pf1N1B4_1775 and Pf1N1B4_1776 are separated by 214 nucleotides Pf1N1B4_1776 and Pf1N1B4_1777 are separated by 225 nucleotides
Pf1N1B4_1774 - Ribosomal protein S6 glutaminyl transferase, at 2,029,147 to 2,030,052
_1774
Pf1N1B4_1775 - hypothetical protein, at 2,030,049 to 2,030,528
_1775
Pf1N1B4_1776 - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog), at 2,030,743 to 2,031,150
_1776
Pf1N1B4_1777 - 33 kDa chaperonin (Heat shock protein 33) (HSP33), at 2,031,376 to 2,032,278
_1777
Position (kb)
2030
2031 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2029.155 kb on + strand at 2029.156 kb on - strand at 2029.156 kb on - strand at 2029.174 kb on - strand at 2029.209 kb on + strand at 2029.209 kb on + strand at 2029.209 kb on + strand at 2029.210 kb on - strand at 2029.210 kb on - strand at 2029.210 kb on - strand at 2029.210 kb on - strand at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.517 kb on + strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.518 kb on - strand, within Pf1N1B4_1774 at 2029.632 kb on + strand, within Pf1N1B4_1774 at 2029.632 kb on + strand, within Pf1N1B4_1774 at 2029.632 kb on + strand, within Pf1N1B4_1774 at 2029.633 kb on - strand at 2029.633 kb on - strand, within Pf1N1B4_1774 at 2029.633 kb on - strand, within Pf1N1B4_1774 at 2029.633 kb on - strand, within Pf1N1B4_1774 at 2029.633 kb on - strand, within Pf1N1B4_1774 at 2029.633 kb on - strand, within Pf1N1B4_1774 at 2029.838 kb on + strand, within Pf1N1B4_1774 at 2029.940 kb on + strand, within Pf1N1B4_1774 at 2029.940 kb on + strand, within Pf1N1B4_1774 at 2029.940 kb on + strand, within Pf1N1B4_1774 at 2029.940 kb on + strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.941 kb on - strand, within Pf1N1B4_1774 at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.984 kb on + strand at 2029.985 kb on - strand at 2029.985 kb on - strand at 2029.985 kb on - strand at 2029.985 kb on - strand at 2029.985 kb on - strand at 2029.985 kb on - strand at 2029.985 kb on - strand at 2030.015 kb on + strand at 2030.015 kb on + strand at 2030.016 kb on - strand at 2030.016 kb on - strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.072 kb on + strand at 2030.073 kb on - strand at 2030.073 kb on - strand at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.100 kb on + strand, within Pf1N1B4_1775 at 2030.101 kb on - strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.104 kb on + strand, within Pf1N1B4_1775 at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.105 kb on - strand at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.105 kb on - strand at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.105 kb on - strand, within Pf1N1B4_1775 at 2030.160 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.251 kb on + strand, within Pf1N1B4_1775 at 2030.252 kb on - strand, within Pf1N1B4_1775 at 2030.282 kb on + strand, within Pf1N1B4_1775 at 2030.282 kb on + strand, within Pf1N1B4_1775 at 2030.593 kb on + strand at 2030.593 kb on + strand at 2030.593 kb on + strand at 2030.614 kb on + strand at 2030.614 kb on + strand at 2030.614 kb on + strand at 2030.614 kb on + strand at 2030.614 kb on + strand at 2030.614 kb on + strand at 2030.614 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.618 kb on + strand at 2030.666 kb on + strand at 2030.666 kb on + strand at 2030.666 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.708 kb on + strand at 2030.721 kb on + strand at 2030.721 kb on + strand at 2030.811 kb on + strand, within Pf1N1B4_1776 at 2031.001 kb on + strand, within Pf1N1B4_1776 at 2031.001 kb on + strand, within Pf1N1B4_1776 at 2031.148 kb on + strand at 2031.148 kb on + strand at 2031.197 kb on + strand at 2031.197 kb on + strand at 2031.198 kb on - strand at 2031.205 kb on + strand at 2031.206 kb on - strand at 2031.206 kb on - strand at 2031.229 kb on + strand at 2031.229 kb on + strand at 2031.285 kb on + strand at 2031.285 kb on + strand at 2031.286 kb on - strand at 2031.375 kb on + strand at 2031.386 kb on + strand at 2031.462 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 2,029,155 + +1.6 2,029,156 - +0.8 2,029,156 - +2.6 2,029,174 - +0.7 2,029,209 + +1.8 2,029,209 + -2.2 2,029,209 + +0.8 2,029,210 - -0.6 2,029,210 - -2.6 2,029,210 - +1.8 2,029,210 - -0.4 2,029,517 + Pf1N1B4_1774 0.41 +1.2 2,029,517 + Pf1N1B4_1774 0.41 -0.5 2,029,517 + Pf1N1B4_1774 0.41 +3.4 2,029,517 + Pf1N1B4_1774 0.41 +1.2 2,029,517 + Pf1N1B4_1774 0.41 -1.5 2,029,517 + Pf1N1B4_1774 0.41 +3.7 2,029,517 + Pf1N1B4_1774 0.41 +2.0 2,029,518 - Pf1N1B4_1774 0.41 +0.8 2,029,518 - Pf1N1B4_1774 0.41 +1.4 2,029,518 - Pf1N1B4_1774 0.41 +1.1 2,029,518 - Pf1N1B4_1774 0.41 +0.7 2,029,518 - Pf1N1B4_1774 0.41 +1.5 2,029,518 - Pf1N1B4_1774 0.41 -0.4 2,029,518 - Pf1N1B4_1774 0.41 +0.5 2,029,518 - Pf1N1B4_1774 0.41 +0.6 2,029,518 - Pf1N1B4_1774 0.41 +0.1 2,029,518 - Pf1N1B4_1774 0.41 +0.6 2,029,518 - Pf1N1B4_1774 0.41 +0.6 2,029,518 - Pf1N1B4_1774 0.41 +1.0 2,029,518 - Pf1N1B4_1774 0.41 +1.4 2,029,518 - Pf1N1B4_1774 0.41 +0.5 2,029,518 - Pf1N1B4_1774 0.41 +1.0 2,029,518 - Pf1N1B4_1774 0.41 -0.6 2,029,632 + Pf1N1B4_1774 0.54 +0.9 2,029,632 + Pf1N1B4_1774 0.54 +1.0 2,029,632 + Pf1N1B4_1774 0.54 +0.4 2,029,633 - +0.8 2,029,633 - Pf1N1B4_1774 0.54 -0.8 2,029,633 - Pf1N1B4_1774 0.54 +0.4 2,029,633 - Pf1N1B4_1774 0.54 +2.4 2,029,633 - Pf1N1B4_1774 0.54 +1.1 2,029,633 - Pf1N1B4_1774 0.54 +0.1 2,029,838 + Pf1N1B4_1774 0.76 -0.2 2,029,940 + Pf1N1B4_1774 0.88 +0.4 2,029,940 + Pf1N1B4_1774 0.88 +0.6 2,029,940 + Pf1N1B4_1774 0.88 -1.8 2,029,940 + Pf1N1B4_1774 0.88 -0.2 2,029,941 - Pf1N1B4_1774 0.88 +1.0 2,029,941 - Pf1N1B4_1774 0.88 -1.2 2,029,941 - Pf1N1B4_1774 0.88 +0.2 2,029,941 - Pf1N1B4_1774 0.88 +0.0 2,029,941 - Pf1N1B4_1774 0.88 -1.4 2,029,941 - Pf1N1B4_1774 0.88 +0.2 2,029,941 - Pf1N1B4_1774 0.88 -0.4 2,029,941 - Pf1N1B4_1774 0.88 +1.0 2,029,941 - Pf1N1B4_1774 0.88 -0.5 2,029,941 - Pf1N1B4_1774 0.88 +1.0 2,029,984 + +0.2 2,029,984 + +0.5 2,029,984 + +0.6 2,029,984 + +2.0 2,029,984 + -1.6 2,029,984 + +0.0 2,029,984 + +0.5 2,029,984 + +0.9 2,029,985 - -0.2 2,029,985 - +1.4 2,029,985 - -1.0 2,029,985 - +1.0 2,029,985 - -0.4 2,029,985 - +0.8 2,029,985 - +1.8 2,030,015 + +1.5 2,030,015 + +0.4 2,030,016 - +0.5 2,030,016 - +1.4 2,030,072 + -0.2 2,030,072 + +1.4 2,030,072 + +1.1 2,030,072 + +0.2 2,030,072 + +1.0 2,030,072 + +0.2 2,030,072 + +3.0 2,030,072 + -0.9 2,030,072 + +0.4 2,030,072 + +0.2 2,030,072 + +2.7 2,030,072 + -1.2 2,030,073 - +0.4 2,030,073 - -0.2 2,030,100 + Pf1N1B4_1775 0.11 -0.9 2,030,100 + Pf1N1B4_1775 0.11 -1.4 2,030,100 + Pf1N1B4_1775 0.11 -0.4 2,030,100 + Pf1N1B4_1775 0.11 -2.2 2,030,100 + Pf1N1B4_1775 0.11 +2.0 2,030,100 + Pf1N1B4_1775 0.11 +1.8 2,030,100 + Pf1N1B4_1775 0.11 -1.4 2,030,100 + Pf1N1B4_1775 0.11 +0.8 2,030,101 - Pf1N1B4_1775 0.11 +1.0 2,030,104 + Pf1N1B4_1775 0.11 +1.1 2,030,104 + Pf1N1B4_1775 0.11 +1.1 2,030,104 + Pf1N1B4_1775 0.11 +1.4 2,030,104 + Pf1N1B4_1775 0.11 +3.2 2,030,104 + Pf1N1B4_1775 0.11 +1.9 2,030,104 + Pf1N1B4_1775 0.11 +0.2 2,030,104 + Pf1N1B4_1775 0.11 -1.1 2,030,104 + Pf1N1B4_1775 0.11 +1.7 2,030,104 + Pf1N1B4_1775 0.11 +0.2 2,030,104 + Pf1N1B4_1775 0.11 +0.4 2,030,104 + Pf1N1B4_1775 0.11 -0.2 2,030,104 + Pf1N1B4_1775 0.11 +3.3 2,030,104 + +0.4 2,030,104 + Pf1N1B4_1775 0.11 +0.1 2,030,104 + Pf1N1B4_1775 0.11 +1.0 2,030,104 + Pf1N1B4_1775 0.11 +0.6 2,030,104 + Pf1N1B4_1775 0.11 +1.5 2,030,104 + Pf1N1B4_1775 0.11 -1.8 2,030,104 + Pf1N1B4_1775 0.11 +2.2 2,030,104 + Pf1N1B4_1775 0.11 -0.6 2,030,105 - Pf1N1B4_1775 0.12 +2.6 2,030,105 - Pf1N1B4_1775 0.12 +0.6 2,030,105 - Pf1N1B4_1775 0.12 +0.8 2,030,105 - +1.4 2,030,105 - Pf1N1B4_1775 0.12 +1.4 2,030,105 - -1.6 2,030,105 - Pf1N1B4_1775 0.12 +1.2 2,030,105 - Pf1N1B4_1775 0.12 +0.1 2,030,105 - Pf1N1B4_1775 0.12 +0.9 2,030,160 + Pf1N1B4_1775 0.23 +1.4 2,030,251 + Pf1N1B4_1775 0.42 -0.0 2,030,251 + Pf1N1B4_1775 0.42 +1.6 2,030,251 + Pf1N1B4_1775 0.42 +2.2 2,030,251 + Pf1N1B4_1775 0.42 -0.4 2,030,251 + Pf1N1B4_1775 0.42 -1.4 2,030,251 + Pf1N1B4_1775 0.42 +0.4 2,030,251 + Pf1N1B4_1775 0.42 +1.8 2,030,251 + Pf1N1B4_1775 0.42 -1.2 2,030,251 + Pf1N1B4_1775 0.42 +0.8 2,030,252 - Pf1N1B4_1775 0.42 -1.2 2,030,282 + Pf1N1B4_1775 0.49 +2.2 2,030,282 + Pf1N1B4_1775 0.49 +1.4 2,030,593 + +2.6 2,030,593 + +1.1 2,030,593 + -0.8 2,030,614 + +2.0 2,030,614 + +0.4 2,030,614 + +0.9 2,030,614 + +1.0 2,030,614 + -0.2 2,030,614 + -0.0 2,030,614 + +2.7 2,030,618 + +0.0 2,030,618 + +0.3 2,030,618 + +0.4 2,030,618 + -0.2 2,030,618 + +1.1 2,030,618 + +1.0 2,030,618 + +2.4 2,030,618 + -1.2 2,030,618 + +1.8 2,030,618 + +1.4 2,030,666 + +0.4 2,030,666 + -1.9 2,030,666 + -0.6 2,030,708 + -1.6 2,030,708 + -0.2 2,030,708 + +1.1 2,030,708 + +1.0 2,030,708 + -0.5 2,030,708 + -0.9 2,030,708 + -0.8 2,030,708 + +0.8 2,030,708 + +1.0 2,030,708 + -1.9 2,030,708 + +1.8 2,030,708 + +0.4 2,030,721 + -0.2 2,030,721 + +0.4 2,030,811 + Pf1N1B4_1776 0.17 +1.4 2,031,001 + Pf1N1B4_1776 0.63 +3.1 2,031,001 + Pf1N1B4_1776 0.63 +1.1 2,031,148 + -0.4 2,031,148 + -1.6 2,031,197 + +2.2 2,031,197 + +0.4 2,031,198 - +1.0 2,031,205 + -0.3 2,031,206 - -0.6 2,031,206 - -0.9 2,031,229 + +0.5 2,031,229 + +0.4 2,031,285 + +1.4 2,031,285 + -0.2 2,031,286 - +1.8 2,031,375 + +1.4 2,031,386 + +0.3 2,031,462 + -0.4
Or see this region's nucleotide sequence