Experiment: Erythromycin 12.5 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Atu5176 and Atu5177 are separated by 246 nucleotides Atu5177 and Atu5178 are separated by 9 nucleotides
Atu5176: Atu5176 - two component sensor kinase, at 172,229 to 173,578
Atu5176
Atu5177: Atu5177 - efflux protein, at 173,825 to 175,018
Atu5177
Atu5178: Atu5178 - ABC transporter nucleotide binding/ATPase, at 175,028 to 176,974
Atu5178
Position (kb) 173
174
175
176 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 172.835 kb on + strand, within Atu5176 at 172.862 kb on + strand, within Atu5176 at 172.994 kb on - strand, within Atu5176 at 172.999 kb on + strand, within Atu5176 at 172.999 kb on - strand, within Atu5176 at 173.025 kb on + strand, within Atu5176 at 173.033 kb on - strand, within Atu5176 at 173.033 kb on - strand, within Atu5176 at 173.033 kb on - strand, within Atu5176 at 173.042 kb on - strand, within Atu5176 at 173.092 kb on - strand, within Atu5176 at 173.143 kb on - strand, within Atu5176 at 173.294 kb on + strand, within Atu5176 at 173.306 kb on + strand, within Atu5176 at 173.330 kb on - strand, within Atu5176 at 173.411 kb on - strand, within Atu5176 at 173.419 kb on - strand, within Atu5176 at 173.436 kb on + strand, within Atu5176 at 173.442 kb on - strand, within Atu5176 at 173.444 kb on - strand at 173.458 kb on + strand at 173.458 kb on + strand at 173.463 kb on - strand at 173.508 kb on + strand at 173.547 kb on + strand at 173.574 kb on + strand at 173.872 kb on + strand at 174.115 kb on + strand, within Atu5177 at 174.123 kb on - strand, within Atu5177 at 174.123 kb on - strand, within Atu5177 at 174.148 kb on + strand, within Atu5177 at 174.154 kb on + strand, within Atu5177 at 174.154 kb on + strand, within Atu5177 at 174.162 kb on - strand, within Atu5177 at 174.190 kb on + strand, within Atu5177 at 174.205 kb on - strand, within Atu5177 at 174.248 kb on - strand, within Atu5177 at 174.249 kb on + strand, within Atu5177 at 174.278 kb on + strand, within Atu5177 at 174.288 kb on - strand, within Atu5177 at 174.309 kb on - strand, within Atu5177 at 174.331 kb on + strand, within Atu5177 at 174.348 kb on + strand, within Atu5177 at 174.362 kb on + strand, within Atu5177 at 174.362 kb on + strand, within Atu5177 at 174.374 kb on + strand, within Atu5177 at 174.445 kb on + strand, within Atu5177 at 174.451 kb on - strand, within Atu5177 at 174.489 kb on + strand, within Atu5177 at 174.497 kb on - strand, within Atu5177 at 174.606 kb on + strand, within Atu5177 at 174.625 kb on - strand, within Atu5177 at 174.685 kb on + strand, within Atu5177 at 174.685 kb on + strand, within Atu5177 at 174.685 kb on + strand, within Atu5177 at 174.685 kb on + strand, within Atu5177 at 174.685 kb on + strand, within Atu5177 at 174.685 kb on + strand, within Atu5177 at 174.693 kb on - strand, within Atu5177 at 174.695 kb on + strand, within Atu5177 at 174.744 kb on - strand, within Atu5177 at 174.744 kb on - strand, within Atu5177 at 174.761 kb on + strand, within Atu5177 at 174.769 kb on - strand, within Atu5177 at 174.769 kb on - strand, within Atu5177 at 174.769 kb on - strand, within Atu5177 at 174.801 kb on + strand, within Atu5177 at 174.801 kb on + strand, within Atu5177 at 174.809 kb on - strand, within Atu5177 at 174.817 kb on + strand, within Atu5177 at 174.869 kb on + strand, within Atu5177 at 174.869 kb on + strand, within Atu5177 at 174.884 kb on + strand, within Atu5177 at 174.892 kb on - strand, within Atu5177 at 174.892 kb on - strand, within Atu5177 at 174.938 kb on - strand at 174.949 kb on - strand at 174.983 kb on - strand at 175.026 kb on - strand at 175.064 kb on - strand at 175.144 kb on - strand at 175.188 kb on + strand at 175.243 kb on - strand, within Atu5178 at 175.314 kb on + strand, within Atu5178 at 175.373 kb on + strand, within Atu5178 at 175.376 kb on - strand, within Atu5178 at 175.401 kb on - strand, within Atu5178 at 175.462 kb on + strand, within Atu5178 at 175.497 kb on + strand, within Atu5178 at 175.521 kb on + strand, within Atu5178 at 175.569 kb on - strand, within Atu5178 at 175.577 kb on + strand, within Atu5178 at 175.617 kb on + strand, within Atu5178 at 175.629 kb on - strand, within Atu5178 at 175.720 kb on + strand, within Atu5178 at 175.771 kb on - strand, within Atu5178 at 175.771 kb on - strand, within Atu5178 at 175.852 kb on - strand, within Atu5178 at 175.933 kb on - strand, within Atu5178 at 175.943 kb on - strand, within Atu5178 at 175.962 kb on - strand, within Atu5178 at 175.975 kb on - strand, within Atu5178 at 175.990 kb on - strand, within Atu5178
Per-strain Table
Position Strand Gene LocusTag Fraction Erythromycin 12.5 ug/mL remove 172,835 + Atu5176 0.45 +0.5 172,862 + Atu5176 0.47 +0.2 172,994 - Atu5176 0.57 +0.4 172,999 + Atu5176 0.57 +0.4 172,999 - Atu5176 0.57 +0.3 173,025 + Atu5176 0.59 -0.0 173,033 - Atu5176 0.60 +0.2 173,033 - Atu5176 0.60 -0.5 173,033 - Atu5176 0.60 +0.5 173,042 - Atu5176 0.60 +1.2 173,092 - Atu5176 0.64 -0.9 173,143 - Atu5176 0.68 -0.2 173,294 + Atu5176 0.79 -0.2 173,306 + Atu5176 0.80 +0.1 173,330 - Atu5176 0.82 -0.1 173,411 - Atu5176 0.88 -1.6 173,419 - Atu5176 0.88 -0.1 173,436 + Atu5176 0.89 -0.9 173,442 - Atu5176 0.90 +0.4 173,444 - +0.2 173,458 + +0.3 173,458 + -0.0 173,463 - +0.0 173,508 + -0.4 173,547 + +0.6 173,574 + +1.5 173,872 + -0.5 174,115 + Atu5177 0.24 -0.2 174,123 - Atu5177 0.25 -1.7 174,123 - Atu5177 0.25 +0.3 174,148 + Atu5177 0.27 -1.4 174,154 + Atu5177 0.28 -0.0 174,154 + Atu5177 0.28 -0.8 174,162 - Atu5177 0.28 -0.4 174,190 + Atu5177 0.31 +0.0 174,205 - Atu5177 0.32 -0.4 174,248 - Atu5177 0.35 -0.6 174,249 + Atu5177 0.36 +1.1 174,278 + Atu5177 0.38 -0.7 174,288 - Atu5177 0.39 -0.6 174,309 - Atu5177 0.41 -0.5 174,331 + Atu5177 0.42 -0.4 174,348 + Atu5177 0.44 +0.5 174,362 + Atu5177 0.45 +1.5 174,362 + Atu5177 0.45 +0.2 174,374 + Atu5177 0.46 +0.2 174,445 + Atu5177 0.52 -1.5 174,451 - Atu5177 0.52 -0.7 174,489 + Atu5177 0.56 -1.0 174,497 - Atu5177 0.56 -1.3 174,606 + Atu5177 0.65 +0.2 174,625 - Atu5177 0.67 -0.0 174,685 + Atu5177 0.72 +1.0 174,685 + Atu5177 0.72 +0.4 174,685 + Atu5177 0.72 -0.4 174,685 + Atu5177 0.72 -0.1 174,685 + Atu5177 0.72 +0.2 174,685 + Atu5177 0.72 +0.7 174,693 - Atu5177 0.73 -1.4 174,695 + Atu5177 0.73 -0.4 174,744 - Atu5177 0.77 +0.2 174,744 - Atu5177 0.77 -0.7 174,761 + Atu5177 0.78 -0.1 174,769 - Atu5177 0.79 -0.7 174,769 - Atu5177 0.79 +0.0 174,769 - Atu5177 0.79 -0.0 174,801 + Atu5177 0.82 +0.1 174,801 + Atu5177 0.82 -0.0 174,809 - Atu5177 0.82 +1.4 174,817 + Atu5177 0.83 -0.3 174,869 + Atu5177 0.87 -1.1 174,869 + Atu5177 0.87 -0.7 174,884 + Atu5177 0.89 +0.1 174,892 - Atu5177 0.89 +0.1 174,892 - Atu5177 0.89 +0.8 174,938 - +0.3 174,949 - +0.7 174,983 - -2.8 175,026 - -0.3 175,064 - -0.6 175,144 - -0.2 175,188 + -0.6 175,243 - Atu5178 0.11 +0.1 175,314 + Atu5178 0.15 +1.5 175,373 + Atu5178 0.18 -0.0 175,376 - Atu5178 0.18 +3.1 175,401 - Atu5178 0.19 -0.4 175,462 + Atu5178 0.22 +0.1 175,497 + Atu5178 0.24 -0.2 175,521 + Atu5178 0.25 -0.1 175,569 - Atu5178 0.28 +0.2 175,577 + Atu5178 0.28 +0.1 175,617 + Atu5178 0.30 +0.7 175,629 - Atu5178 0.31 +0.0 175,720 + Atu5178 0.36 -0.1 175,771 - Atu5178 0.38 -0.1 175,771 - Atu5178 0.38 +2.2 175,852 - Atu5178 0.42 +1.0 175,933 - Atu5178 0.46 -0.7 175,943 - Atu5178 0.47 -0.1 175,962 - Atu5178 0.48 -0.3 175,975 - Atu5178 0.49 +0.0 175,990 - Atu5178 0.49 +0.3
Or see this region's nucleotide sequence