Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2271

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
2,544,371	-		Rv2269c	0.25	-0.9
2,544,371	-		Rv2269c	0.25	+1.0
2,544,491	+		Rv2269c	0.61	-0.2
2,544,491	+		Rv2269c	0.61	-0.1
2,544,545	+		Rv2269c	0.77	-0.3
2,544,678	-				-0.9
2,544,725	+				-0.0
2,544,726	-				-0.1
2,544,726	-				-0.4
2,544,992	+		Rv2270	0.56	+0.2
2,545,113	-		Rv2270	0.79	-0.3
2,545,136	-		Rv2270	0.83	-0.5
2,545,308	+				+0.5
2,545,455	+		Rv2271	0.41	+0.2
2,545,578	+		Rv2271	0.82	+0.2
2,545,597	+		Rv2271	0.88	-0.5
2,545,598	-		Rv2271	0.89	-1.3
2,545,654	+				-0.1
2,545,655	-				-0.5
2,545,655	-				+0.0
2,545,682	+				-1.7
2,546,032	-		Rv2272	0.80	-0.8
2,546,291	+		Rv2273	0.57	-0.1
2,546,291	+		Rv2273	0.57	-0.7
2,546,291	+		Rv2273	0.57	-0.4
2,546,305	-		Rv2273	0.62	-0.4
2,546,490	-				+0.1