Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0594 and Rv0595c are separated by 51 nucleotides Rv0595c and Rv0596c overlap by 4 nucleotides Rv0596c and Rv0597c are separated by 182 nucleotides Rv0597c and Rv0598c are separated by 250 nucleotides Rv0598c and Rv0599c overlap by 4 nucleotides
Rv0594: Rv0594 - Mce-family protein Mce2F, at 693,237 to 694,787
Rv0594
Rv0595c: Rv0595c - Possible toxin VapC4, at 694,839 to 695,231
Rv0595c
Rv0596c: Rv0596c - Possible antitoxin VapB4, at 695,228 to 695,485
Rv0596c
Rv0597c: Rv0597c - Conserved hypothetical protein, at 695,668 to 696,903
Rv0597c
Rv0598c: Rv0598c - Possible toxin VapC27. Contains PIN domain., at 697,154 to 697,567
Rv0598c
Rv0599c: Rv0599c - Possible antitoxin VapB27, at 697,564 to 697,800
Rv0599c
Position (kb) 695
696
697 Strain fitness (log2 ratio) -1
0
1 at 694.675 kb on - strand at 694.700 kb on - strand at 694.700 kb on - strand at 694.700 kb on - strand at 694.700 kb on - strand at 694.720 kb on - strand at 694.848 kb on + strand at 694.986 kb on + strand, within Rv0595c at 694.986 kb on + strand, within Rv0595c at 695.022 kb on + strand, within Rv0595c at 695.050 kb on + strand, within Rv0595c at 695.051 kb on - strand, within Rv0595c at 695.223 kb on + strand at 695.223 kb on + strand at 695.556 kb on - strand at 695.789 kb on + strand at 695.789 kb on + strand at 695.794 kb on + strand, within Rv0597c at 695.794 kb on + strand, within Rv0597c at 695.794 kb on + strand, within Rv0597c at 695.984 kb on - strand, within Rv0597c at 696.326 kb on + strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.703 kb on + strand, within Rv0597c at 696.914 kb on + strand at 697.270 kb on - strand, within Rv0598c at 697.366 kb on + strand, within Rv0598c at 697.432 kb on - strand, within Rv0598c at 697.708 kb on + strand, within Rv0599c at 697.806 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 694,675 - -0.6 694,700 - -0.0 694,700 - +0.2 694,700 - -0.3 694,700 - +1.4 694,720 - +1.1 694,848 + -0.5 694,986 + Rv0595c 0.37 -0.0 694,986 + Rv0595c 0.37 -0.7 695,022 + Rv0595c 0.47 -0.4 695,050 + Rv0595c 0.54 +0.0 695,051 - Rv0595c 0.54 +0.7 695,223 + -0.4 695,223 + -1.4 695,556 - -0.2 695,789 + -1.0 695,789 + -0.1 695,794 + Rv0597c 0.10 -0.1 695,794 + Rv0597c 0.10 -0.4 695,794 + Rv0597c 0.10 -0.3 695,984 - Rv0597c 0.26 -0.2 696,326 + Rv0597c 0.53 -0.7 696,327 - Rv0597c 0.53 -0.3 696,327 - Rv0597c 0.53 -0.1 696,327 - Rv0597c 0.53 -0.2 696,327 - Rv0597c 0.53 -0.5 696,703 + Rv0597c 0.84 -0.5 696,914 + -0.5 697,270 - Rv0598c 0.28 +0.4 697,366 + Rv0598c 0.51 +0.3 697,432 - Rv0598c 0.67 +1.1 697,708 + Rv0599c 0.61 -1.2 697,806 + -0.4
Or see this region's nucleotide sequence