Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1095 and Rv1096 are separated by 86 nucleotides Rv1096 and Rv1097c are separated by 2 nucleotides Rv1097c and Rv1098c overlap by 4 nucleotides
Rv1095: Rv1095 - Probable PHOH-like protein PhoH2 (phosphate starvation-inducible protein PSIH), at 1,222,997 to 1,224,298
Rv1095
Rv1096: Rv1096 - Possible glycosyl hydrolase, at 1,224,385 to 1,225,260
Rv1096
Rv1097c: Rv1097c - Probable membrane glycine and proline rich protein, at 1,225,263 to 1,226,144
Rv1097c
Rv1098c: Rv1098c - Probable fumarase Fum (fumarate hydratase), at 1,226,141 to 1,227,565
Rv1098c
Position (kb) 1224
1225
1226 Strain fitness (log2 ratio) -1
0
1
2 at 1223.427 kb on - strand, within Rv1095 at 1223.547 kb on + strand, within Rv1095 at 1223.865 kb on - strand, within Rv1095 at 1223.865 kb on - strand, within Rv1095 at 1224.714 kb on + strand, within Rv1096 at 1225.100 kb on - strand, within Rv1096 at 1225.259 kb on - strand at 1225.431 kb on - strand, within Rv1097c at 1225.517 kb on - strand, within Rv1097c at 1225.734 kb on - strand, within Rv1097c at 1226.111 kb on - strand at 1226.111 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 1,223,427 - Rv1095 0.33 -0.5 1,223,547 + Rv1095 0.42 +0.1 1,223,865 - Rv1095 0.67 -0.5 1,223,865 - Rv1095 0.67 -0.3 1,224,714 + Rv1096 0.38 -1.1 1,225,100 - Rv1096 0.82 +0.4 1,225,259 - -1.4 1,225,431 - Rv1097c 0.19 -0.3 1,225,517 - Rv1097c 0.29 -0.1 1,225,734 - Rv1097c 0.53 +1.9 1,226,111 - +0.2 1,226,111 - +0.7
Or see this region's nucleotide sequence