Pairwise Alignments

Query, 468 a.a., phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) from Klebsiella michiganensis M5al

Subject, 485 a.a., Probable 6-phosphogluconate dehydrogenase Gnd1 from Mycobacterium tuberculosis H37Rv

 Score =  484 bits (1247), Expect = e-141
 Identities = 245/466 (52%), Positives = 329/466 (70%), Gaps = 5/466 (1%)

Query: 5   QIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIAENPGK-KLVPHYTVQEFVES 63
           QIGV G+AVMG N+A N    GYTV+V NRS  KT+ ++ E+    K V   T+ EF+ +
Sbjct: 12  QIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAA 71

Query: 64  LETPRRILLMVKAGAGTDS--AIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFN 121
           LE PRR+L+MVKAG  TD+   I+ L   ++ GDIIIDGGN  + DT+RR + +   G +
Sbjct: 72  LEKPRRVLIMVKAGEATDADAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLH 131

Query: 122 FIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAGHY 181
           F+G G+SGGEEGAL GPSIMPGG  E+Y+ + P+L++I+A   DG PC T+IG DG+GH+
Sbjct: 132 FVGAGISGGEEGALNGPSIMPGGPAESYQSLGPLLEEISAHV-DGVPCCTHIGPDGSGHF 190

Query: 182 VKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQTFTEWNEGELSSYLIDITKDIFTK 241
           VKMVHNGIEY DMQLI EAY L++ GL L+   +A  FTEWN G+L SYL++IT ++  +
Sbjct: 191 VKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVEITAEVLRQ 250

Query: 242 KDEE-GKYLVDVILDEAANKGTGKWTSQSSLDLGEPLSLITESVFARYISSLKDQRVAAS 300
            D + GK LVDVI+D A  KGTG+WT +S+LDLG P++ I E+VFAR +S    QR AAS
Sbjct: 251 TDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAAS 310

Query: 301 KVLTGPQAKSAGDKAEFVEKVRRALYLGKIVSYAQGFSQLRAASDEYHWDLNYGEIAKIF 360
            + +G   +   D A F E VR+ALY  KIV+YAQGF+Q++A S E+ WD+  G++A I+
Sbjct: 311 GLASGKLGEQPADPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIW 370

Query: 361 RAGCIIRAQFLQKITNAYEQNAGIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPT 420
           R GCIIRA+FL  I  A++ +  +A+L++APYF+   +    + R VV+ A Q GIP P 
Sbjct: 371 RGGCIIRAKFLNHIKEAFDASPNLASLIVAPYFRGAVESAIDSWRRVVSTAAQLGIPTPG 430

Query: 421 FSAAIAYYDSYRSAVLPANLIQAQRDYFGAHTYKRTDKEGVFHTEW 466
           FS+A++YYD+ R+A LPA L QAQRD+FGAHTY R D+ G FHT W
Sbjct: 431 FSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLW 476