SEED Subsystem: Leucine Degradation and HMG-CoA Metabolism in Paraburkholderia bryophila 376MFSha3.1

Role	Gene	Name	4-Methyl-2-oxopentanoic (C)
Acetoacetyl-CoA synthetase (EC 6.2.1.16)	H281DRAFT_02398		+0.1
Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	No genes
Biotin carboxyl carrier protein of methylcrotonyl-CoA carboxylase	No genes
Biotin carboxylase of methylcrotonyl-CoA carboxylase (EC 6.3.4.14)	No genes
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)	No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)	No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)	No genes
Branched-chain amino acid aminotransferase (EC 2.6.1.42)	H281DRAFT_04193		-0.3
	H281DRAFT_05498		-0.1
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)	No genes
Dihydrolipoamide dehydrogenase (EC 1.8.1.4)	No genes
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4)	No genes
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)	H281DRAFT_02101		-4.3
	H281DRAFT_03571		-0.1
	H281DRAFT_03708		-0.1
	H281DRAFT_03709		-0.1
	H281DRAFT_04763		+0.2
	H281DRAFT_04764		+0.4
Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34)	H281DRAFT_05050		+0.3
Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10)	No genes
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)	No genes
Leucine dehydrogenase (EC 1.4.1.9)	No genes
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	H281DRAFT_01343		-2.8
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	H281DRAFT_01345		-3.5
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	H281DRAFT_01344		N.D.
Predicted transcriptional regulator of leucine degradation pathway, MerR family	No genes
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)	H281DRAFT_04495		-2.6
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)	H281DRAFT_04496		N.D.