MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas fluorescens GW456-L13

MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas fluorescens GW456-L13

Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

PfGW456L13_2059

PfGW456L13_2142

PfGW456L13_2177

PfGW456L13_2252

PfGW456L13_2943

PfGW456L13_2947

PfGW456L13_3163

PfGW456L13_3206

PfGW456L13_3261

PfGW456L13_3292

PfGW456L13_3363

PfGW456L13_3960

PfGW456L13_4175

PfGW456L13_4396

PfGW456L13_4856

PfGW456L13_4919

PfGW456L13_4930

PfGW456L13_4999

4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO₂ (EC 1.13.11.27)

PfGW456L13_1425

PfGW456L13_2935

Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H⁺ (EC 1.13.11.5)

PfGW456L13_4962

Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)

PfGW456L13_4960

Fumarylacetoacetase:
4-fumaryl-acetoacetate + H₂O→acetoacetate + fumarate + H⁺ (EC 3.7.1.2)

PfGW456L13_4961

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information