MetaCyc Pathway: L-tyrosine degradation III in Pseudomonas fluorescens FW300-N2C3

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Reactions and Genes methylglyoxal 0.016 vol%
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Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
AO356_01275 -0.7
AO356_03090 +0.0
AO356_03460 +0.1
AO356_03985 -0.0
AO356_06565 +0.1
AO356_06960 +0.3
AO356_12070 -0.1
AO356_12595 -0.0
AO356_16875 -0.1
AO356_19495 +0.1
AO356_19865 -0.1
AO356_19905 +0.2
AO356_20345 -0.5
AO356_21330 -0.1
AO356_22880 +0.1
AO356_24005 -0.2
AO356_24115 -0.0
AO356_24720 +0.2
AO356_24975 +0.3
AO356_25355 -0.2
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2 (EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+ (EC 1.1.1.1)
AO356_00820 +0.3
AO356_04765 -0.2
AO356_05920 -3.6
AO356_14405 +0.1
AO356_20305 -0.7
AO356_28020 +0.6
AO356_29985 +0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information