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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv0675 and Rv0676c are separated by 11 nucleotides
Rv0676c and Rv0677c overlap by 4 nucleotides
Rv0677c and Rv0678 are separated by 84 nucleotides
Rv0678 and Rv0679c are separated by 55 nucleotides
Rv0675: Rv0675 - Probable enoyl-CoA hydratase EchA5 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 774,783 to 775,574
Rv0675
Rv0676c: Rv0676c - Probable conserved transmembrane transport protein MmpL5, at 775,586 to 778,480
Rv0676c
Rv0677c: Rv0677c - Possible conserved membrane protein MmpS5, at 778,477 to 778,905
Rv0677c
Rv0678: Rv0678 - Conserved protein, at 778,990 to 779,487
Rv0678
Rv0679c: Rv0679c - Conserved threonine rich protein, at 779,543 to 780,040
Rv0679c
Group
Condition
Rv0675
Rv0676c
Rv0677c
Rv0678
Rv0679c
stress
7H9 with Clofazimine 0.072 ug/mL
-2.1
-2.9
-1.3
+1.3
-0.2
stress
7H9 with Bedaquiline 0.15 ug/mL
-2.7
-3.7
+0.2
+1.1
-0.1
stress
7H9 with Bedaquiline 0.15 ug/mL
-0.8
-3.7
-1.1
+1.2
-0.7
stress
7H9 with Levofloxacin 0.3 ug/mL
-3.9
-0.1
-0.6
+0.0
-0.2
nitrogen source
L-Alanine 10 mM (N)
-1.3
-2.0
-1.8
+0.2
+0.2
stress
7H9 with Dodecyl Sulfate 0.02 vol%
-3.7
-0.5
+0.3
-0.5
-0.2
stress
7H9 with Irgasan 0.065 mM
-3.7
-0.5
-0.3
+0.2
-0.1
nitrogen source
L-Aspartic Acid 10 mM (N)
-1.4
-1.7
-1.1
+0.2
-0.3
carbon source
L-Aspartic Acid (C)
-2.1
-0.9
-0.3
-0.4
-0.3
stress
7H9 with Levofloxacin 0.3 ug/mL
-3.9
-0.2
+0.1
+0.3
-0.3
stress
7H9 with Nickel (II) chloride 0.6 mM
-2.3
-0.6
-0.6
+0.0
-0.5
nitrogen source
L-Alanine 10 mM (N)
-0.4
-1.6
-2.0
-0.0
+0.2
nitrogen source
L-Glutamic 10 mM (N)
-1.7
-1.2
-1.4
+0.2
+0.3
nitrogen source
L-Serine 10 mM (N)
+0.2
-2.6
-1.6
+0.4
-0.1
nitrogen source
L-Asparagine 10 mM (N)
-0.8
-2.2
-1.3
+0.7
+0.0
stress
7H9 with Clofazimine 0.072 ug/mL
-0.3
-3.0
-1.2
+1.3
-0.3
stress
7H9 with Erythromycin 0.016 mM
-1.0
-1.1
-1.0
+0.4
-0.9
nitrogen source
L-Serine 10 mM (N)
+0.2
-2.6
-1.3
+0.1
+0.2
stress
7H9 with Clofazimine 0.45 ug/mL
-0.4
-2.9
-1.6
+2.1
-0.6
stress
7H9 with Clofazimine 0.45 ug/mL
-2.1
-3.0
-0.8
+2.1
+0.4
carbon source
Glycerol (C)
-1.7
-1.0
-0.6
+0.4
-0.5
no stress control
no stress control
-3.7
-0.2
+0.8
-0.3
+0.1
nitrogen source
L-Asparagine 10 mM (N)
-0.8
-1.5
-1.2
+0.6
-0.2
stress
7H9 with Linezolid 0.3 ug/mL
-3.8
-0.2
+0.7
+0.3
-0.1
nitrogen source
L-Glutamic 10 mM (N)
-1.1
-1.2
-1.2
+0.1
+0.4
no stress control
no stress control
-3.4
-0.0
+0.4
-0.1
+0.3
nitrogen source
Urea 10mM (N)
-1.5
-0.8
-1.1
+0.7
+0.3
nitrogen source
Glycine 10 mM (N)
+0.6
-1.9
-1.4
+0.4
+0.2
stress
7H9 with Econazole nitrate salt 0.0082 mM
+0.2
-1.9
-1.8
+2.4
-0.1
stress
7H9 with Econazole nitrate salt 0.0082 mM
-0.3
-1.7
-1.2
+2.0
+0.2
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