Experiment set9IT088 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Cephalothin sodium salt 0.0000078125 mM

200 most important genes:

  gene name fitness t score description  
b4150 ampC -5.4 -6.4 beta-lactamase/D-alanine carboxypeptidase (NCBI) conserved
b1105 ycfM -5.3 -3.7 predicted outer membrane lipoprotein (NCBI) compare
b0433 ampG -5.2 -7.9 muropeptide transporter (NCBI) conserved
b4392 slt -5.0 -10.6 soluble lytic murein transglycosylase (VIMSS) conserved
b0381 ddlA -5.0 -4.8 D-alanylalanine synthetase (NCBI) compare
b1192 ldcA -4.6 -3.2 L,D-carboxypeptidase A (NCBI) compare
b0728 sucC -4.6 -5.5 succinyl-CoA synthetase subunit beta (NCBI) compare
b2553 glnB -4.5 -3.1 regulatory protein P-II for glutamine synthetase (NCBI) compare
b0088 murD -4.3 -2.6 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b0434 yajG -4.2 -8.0 putative polymerase/proteinase (VIMSS) conserved
b3742 mioC -4.2 -5.6 flavodoxin (NCBI) compare
b4238 nrdD -4.1 -17.6 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b4053 alr -4.1 -6.9 alanine racemase (NCBI) compare
b0149 mrcB -4.1 -2.8 penicillin-binding protein 1b (NCBI) compare
b3609 secB -4.0 -2.7 export protein SecB (NCBI) compare
b0957 ompA -4.0 -2.7 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1658 purR -3.9 -3.8 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b0436 tig -3.8 -7.3 trigger factor (NCBI) compare
b0059 hepA -3.7 -14.2 ATP-dependent helicase HepA (NCBI) compare
b4237 nrdG -3.7 -8.9 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b3150 yraP -3.6 -6.4 hypothetical protein (NCBI) compare
b0110 ampD -3.6 -6.5 N-acetyl-anhydromuranmyl-L-alanine amidase (NCBI) conserved
b3764 yifE -3.4 -5.2 hypothetical protein (NCBI) compare
b3341 rpsG -3.4 -2.0 30S ribosomal protein S7 (NCBI) compare
b1150 ymfR -3.4 -1.2 e14 prophage; predicted protein (NCBI) compare
b2701 mltB -3.3 -7.3 membrane-bound lytic murein transglycosylase B (NCBI) compare
b0237 pepD -3.3 -6.7 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b1101 ptsG -3.3 -10.1 fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) compare
b0605 ahpC -3.3 -4.4 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1429 tehA -3.2 -2.0 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1582 ynfA -3.2 -3.1 hypothetical protein (NCBI) compare
b3195 yrbF -3.2 -10.4 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0902 pflA -3.1 -7.5 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b4201 priB -3.0 -2.9 primosomal replication protein N (NCBI) compare
b3032 cpdA -3.0 -7.9 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b0912 ihfB -2.9 -3.2 integration host factor subunit beta (NCBI) compare
b2813 mltA -2.9 -9.6 membrane-bound lytic murein transglycosylase A (NCBI) compare
b0741 pal -2.9 -2.0 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1104 ycfL -2.9 -2.3 hypothetical protein (NCBI) compare
b3617 kbl -2.9 -6.4 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b3163 nlpI -2.9 -4.4 hypothetical protein (NCBI) compare
b3164 pnp -2.9 -2.0 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0632 dacA -2.9 -7.7 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b3194 yrbE -2.8 -11.4 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3868 glnG -2.8 -3.8 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b3616 tdh -2.8 -4.2 L-threonine 3-dehydrogenase (NCBI) compare
b1827 kdgR -2.8 -3.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b1850 eda -2.7 -2.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3226 yhcK -2.7 -4.7 putative FADA-type transcriptional regulator (VIMSS) compare
b2896 ygfX -2.7 -6.1 hypothetical protein (NCBI) conserved
b1103 ycfF -2.7 -1.3 orf, hypothetical protein (VIMSS) compare
b2174 b2174 -2.6 -8.2 orf, hypothetical protein (VIMSS) compare
b4025 pgi -2.6 -7.9 glucose-6-phosphate isomerase (NCBI) compare
b1758 b1758 -2.6 -1.3 putative cytochrome oxidase (VIMSS) compare
b3193 yrbD -2.6 -9.3 predicted ABC-type organic solvent transporter (NCBI) compare
b4220 ytfM -2.6 -11.8 predicted outer membrane protein and surface antigen (NCBI) compare
b1684 sufA -2.6 -3.0 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b3649 rpoZ -2.6 -3.0 DNA-directed RNA polymerase subunit omega (NCBI) compare
b0737 tolQ -2.5 -1.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0633 rlpA -2.5 -9.0 minor lipoprotein (NCBI) compare
b4480 hdfR -2.5 -5.6 transcriptional regulator HdfR (NCBI) compare
b2317 dedA -2.5 -4.5 conserved inner membrane protein (NCBI) compare
b3792 wzxE -2.5 -3.0 O-antigen translocase (NCBI) compare
b2576 srmB -2.5 -1.7 ATP-dependent RNA helicase (NCBI) compare
b3388 damX -2.5 -14.2 hypothetical protein (NCBI) compare
b3205 yhbJ -2.5 -3.3 hypothetical protein (NCBI) compare
b1651 gloA -2.5 -3.0 glyoxalase I, Ni-dependent (NCBI) compare
b0740 tolB -2.5 -1.7 translocation protein TolB precursor (NCBI) compare
b3191 yrbB -2.4 -8.5 orf, hypothetical protein (VIMSS) compare
b2318 truA -2.4 -2.7 tRNA pseudouridine synthase A (NCBI) compare
b3166 truB -2.3 -6.3 tRNA pseudouridine synthase B (NCBI) compare
b2479 gcvR -2.3 -4.8 transcriptional regulation of gcv operon (VIMSS) compare
b1304 pspA -2.3 -3.7 regulatory protein for phage-shock-protein operon (NCBI) compare
b3836 b3836 -2.3 -4.8 orf, hypothetical protein (VIMSS) compare
b4221 ytfN -2.3 -11.5 hypothetical protein (NCBI) compare
b1949 fliQ -2.3 -2.5 flagellar biosynthesis protein Q (NCBI) compare
b0729 sucD -2.3 -2.8 succinyl-CoA synthetase subunit alpha (NCBI) compare
b2807 ygdD -2.3 -4.9 conserved inner membrane protein (NCBI) compare
b3349 slyD -2.3 -6.5 FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) (NCBI) compare
b2346 vacJ -2.3 -7.1 predicted lipoprotein (NCBI) compare
b3192 yrbC -2.3 -8.9 predicted ABC-type organic solvent transporter (NCBI) compare
b0211 mltD -2.3 -6.1 predicted membrane-bound lytic murein transglycosylase D (NCBI) conserved
b0081 mraZ -2.2 -5.0 hypothetical protein (NCBI) compare
b1107 nagZ -2.2 -4.1 beta-hexosaminidase (NCBI) compare
b2727 hypB -2.2 -5.2 GTP hydrolase involved in nickel liganding into hydrogenases (NCBI) compare
b1493 gadB -2.2 -0.7 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b3131 agaR -2.2 -3.8 DNA-binding transcriptional dual regulator (NCBI) compare
b3871 bipA -2.1 -8.2 GTP-binding protein (NCBI) compare
b2350 yfdG -2.1 -4.4 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b3094 exuR -2.1 -3.5 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b3610 grxC -2.1 -5.5 glutaredoxin 3 (NCBI) compare
b2730 hypE -2.0 -7.4 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein (RefSeq) compare
b0623 cspE -2.0 -1.6 cold shock protein E (NCBI) compare
b1183 umuD -2.0 -1.6 DNA polymerase V, subunit D (NCBI) compare
b4451 ryhB -2.0 -1.7 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b4206 ytfB -2.0 -7.1 orf, hypothetical protein (VIMSS) compare
b3839 tatC -2.0 -5.1 TatABCE protein translocation system subunit (NCBI) compare
b3655 yicH -2.0 -10.3 hypothetical protein (NCBI) compare
b4294 insA-7 -2.0 -2.1 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b0145 dksA -2.0 -2.3 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3636 rpmG -2.0 -1.3 50S ribosomal protein L33 (NCBI) compare
b1924 fliD -2.0 -5.8 flagellar capping protein (NCBI) conserved
b4233 mpl -2.0 -7.7 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (NCBI) conserved
b4568 ytjA -2.0 -1.7 predicted protein (RefSeq) compare
b4324 uxuR -1.9 -8.6 DNA-binding transcriptional repressor (NCBI) compare
b4585 sroB -1.9 -1.0 Novel sRNA, function unknown (RefSeq) compare
b1889 motB -1.9 -4.2 flagellar motor protein MotB (NCBI) compare
b2620 smpB -1.9 -1.3 SsrA-binding protein (NCBI) compare
b1241 adhE -1.9 -8.0 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) compare
b4402 yjjY -1.9 -1.0 hypothetical protein (NCBI) compare
b0560 nohB -1.9 -2.6 DLP12 prophage; DNA packaging protein (NCBI) compare
b2517 yfgB -1.9 -7.7 predicted enzyme (NCBI) conserved
b2528 iscA -1.9 -1.8 iron-sulfur cluster assembly protein (NCBI) compare
b4046 yjbK -1.9 -6.0 putative regulator (VIMSS) compare
b1476 fdnI -1.9 -0.6 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b0051 ksgA -1.9 -2.2 dimethyladenosine transferase (NCBI) compare
b1634 tppB -1.9 -4.5 putative tripeptide transporter permease (NCBI) compare
b0820 ybiT -1.9 -7.2 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b0877 ybjX -1.8 -5.0 hypothetical protein (NCBI) compare
b1575 dicB -1.8 -1.2 Qin prophage; cell division inhibition protein (NCBI) compare
b3928 yiiU -1.8 -5.1 hypothetical protein (NCBI) compare
b3096 yqjB -1.8 -3.3 hypothetical protein (NCBI) compare
b2217 rcsB -1.8 -3.8 DNA-binding response regulator in two-component regulatory system with RcsC and YojN (NCBI) compare
b3545 proK -1.8 -1.3 tRNA-Pro (NCBI) compare
b3237 argR -1.8 -3.8 arginine repressor (NCBI) compare
b1945 fliM -1.8 -6.1 flagellar motor switch protein M (NCBI) compare
b2809 b2809 -1.8 -2.7 orf, hypothetical protein (VIMSS) compare
b0092 ddlB -1.8 -3.8 D-alanylalanine synthetase (NCBI) compare
b3611 yibN -1.8 -4.6 predicted rhodanese-related sulfurtransferase (NCBI) compare
b1125 potB -1.8 -4.3 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b3838 tatB -1.7 -6.3 sec-independent translocase (NCBI) compare
b1531 marA -1.7 -2.2 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b3229 sspA -1.7 -1.7 stringent starvation protein A (NCBI) compare
b3794 rffM -1.7 -5.9 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b2997 hybO -1.7 -6.0 hydrogenase 2, small subunit (NCBI) compare
b0739 tolA -1.7 -1.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1848 yebG -1.7 -1.1 conserved protein regulated by LexA (NCBI) compare
b1613 manA -1.7 -2.1 mannose-6-phosphate isomerase (VIMSS) compare
b2175 spr -1.7 -3.0 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b0742 ybgF -1.7 -4.3 hypothetical protein (NCBI) compare
b1109 ndh -1.7 -3.8 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b0579 ybdF -1.7 -2.0 hypothetical protein (NCBI) compare
b4191 ulaR -1.7 -2.9 DNA-binding transcriptional dual regulator (NCBI) compare
b1832 yebR -1.6 -3.7 free methionine-(R)-sulfoxide reductase (RefSeq) compare
b2683 ygaH -1.6 -3.6 predicted inner membrane protein (NCBI) compare
b2991 hybF -1.6 -5.2 protein involved with the maturation of hydrogenases 1 and 2 (NCBI) compare
b2939 yqgB -1.6 -1.1 predicted protein (RefSeq) compare
b4139 aspA -1.6 -6.5 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b3207 yrbL -1.6 -4.7 hypothetical protein (NCBI) compare
b3791 rffA -1.6 -6.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0113 pdhR -1.6 -4.0 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b0340 cynS -1.6 -2.9 cyanate hydratase (NCBI) compare
b1946 fliN -1.6 -3.4 flagellar motor switch protein (NCBI) compare
b4503 yafF -1.6 -0.8 no description compare
b0225 yafQ -1.6 -3.2 predicted toxin of the YafQ-DinJ toxin-antitoxin system (NCBI) compare
b3930 menA -1.6 -10.2 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b3476 nikA -1.5 -7.0 nickel transporter subunit (NCBI) compare
b0814 ompX -1.5 -3.3 outer membrane protein X (NCBI) compare
b3253 yhdH -1.5 -6.6 predicted oxidoreductase, Zn-dependent and NAD(P)-binding (NCBI) compare
b4414 tff -1.5 -1.5 unknown RNA (NCBI) compare
b3933 ftsN -1.5 -7.7 essential cell division protein (NCBI) compare
b3082 ygjM -1.5 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3479 nikD -1.5 -7.0 nickel transporter subunit (NCBI) compare
b0014 dnaK -1.5 -1.4 molecular chaperone DnaK (NCBI) compare
b3158 yhbU -1.5 -6.2 predicted peptidase (collagenase-like) (NCBI) compare
b3478 nikC -1.5 -5.8 nickel transporter subunit (NCBI) compare
b2996 hybA -1.5 -5.6 hydrogenase 2 4Fe-4S ferredoxin-type component (NCBI) compare
b2906 visC -1.5 -5.0 hypothetical protein (NCBI) compare
b4631 ykgQ -1.5 -1.2 no description compare
b1620 malI -1.5 -2.2 DNA-binding transcriptional repressor (NCBI) compare
b2366 dsdA -1.5 -3.4 D-serine dehydratase (NCBI) compare
b4515 ybgT -1.5 -1.2 hypothetical protein (NCBI) compare
b1082 flgK -1.5 -3.7 flagellar hook-associated protein K (NCBI) compare
b1882 cheY -1.4 -0.5 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1556 b1556 -1.4 -1.8 orf, hypothetical protein (VIMSS) compare
b1881 cheZ -1.4 -3.6 chemotaxis regulator, protein phosphatase for CheY (NCBI) compare
b0785 moaE -1.4 -4.2 molybdopterin synthase, large subunit (NCBI) compare
b2666 yqaE -1.4 -3.4 predicted membrane protein (NCBI) compare
b1298 ycjL -1.4 -3.9 probable amidotransferase subunit (VIMSS) compare
b4203 rplI -1.4 -2.7 50S ribosomal protein L9 (NCBI) compare
b2282 nuoH -1.4 -2.6 NADH dehydrogenase subunit H (NCBI) compare
b2729 hypD -1.4 -6.0 protein required for maturation of hydrogenases (NCBI) compare
b0247 ykfG -1.4 -0.9 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b1814 sdaA -1.4 -2.5 L-serine deaminase I (NCBI) compare
b0481 ybaK -1.4 -2.8 hypothetical protein (NCBI) compare
b1887 cheW -1.4 -4.9 purine-binding chemotaxis protein (NCBI) compare
b2082 ogrK -1.4 -2.4 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b4242 mgtA -1.4 -6.2 magnesium transporter (NCBI) compare
b0009 mog -1.4 -5.7 molybdenum cofactor biosynthesis protein (NCBI) compare
b2994 hybC -1.4 -6.5 hydrogenase 2, large subunit (NCBI) compare
b2313 cvpA -1.4 -3.9 membrane protein required for colicin V production (NCBI) compare
b3786 rffE -1.4 -7.9 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b0339 cynT -1.4 -2.6 carbonic anhydrase (NCBI) compare
b1818 manY -1.4 -1.1 mannose-specific enzyme IIC component of PTS (NCBI) compare
b3755 yieP -1.4 -3.3 predicted transcriptional regulator (NCBI) compare
b3469 zntA -1.4 -4.3 zinc, cobalt and lead efflux system (NCBI) compare
b4180 rlmB -1.4 -5.7 23S rRNA (Gm2251)-methyltransferase (NCBI) compare
b0469 apt -1.3 -4.3 adenine phosphoribosyltransferase (NCBI) compare
b3247 cafA -1.3 -5.4 bundles of cytoplasmic filaments (VIMSS) compare
b0053 surA -1.3 -4.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare


Specific Phenotypes

For 78 genes in this experiment

For stress Cephalothin sodium salt in Escherichia coli BW25113

For stress Cephalothin sodium salt across organisms