Experiment set76S714 for Escherichia coli BW25113

Compare to:

NoPhageControl|T7phage

200 most important genes:

  gene name fitness t score description  
b1429 tehA -4.6 -3.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b0726 sucA -3.9 -3.8 alpha-ketoglutarate decarboxylase (NCBI) compare
b1361 ydaW -3.3 -1.4 orf, hypothetical protein (VIMSS) compare
b3977 tyrU -3.1 -1.3 tRNA-Tyr (NCBI) compare
b3500 gor -3.1 -2.1 glutathione reductase (NCBI) compare
b0683 fur -3.0 -2.0 ferric uptake regulator (NCBI) compare
b0053 surA -2.6 -1.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1506 yneL -2.5 -2.4 predicted transcriptional regulator (NCBI) compare
b3183 obgE -2.5 -1.7 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3839 tatC -2.2 -7.5 TatABCE protein translocation system subunit (NCBI) compare
b0740 tolB -2.1 -3.5 translocation protein TolB precursor (NCBI) compare
b0142 folK -2.1 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b2830 nudH -2.1 -1.4 dinucleoside polyphosphate hydrolase (NCBI) compare
b1192 ldcA -2.0 -4.1 L,D-carboxypeptidase A (NCBI) compare
b3390 aroK -2.0 -2.3 shikimate kinase I (NCBI) compare
b2330 yfcB -1.9 -2.5 putative adenine-specific methylase (VIMSS) compare
b1332 ynaJ -1.9 -1.1 predicted inner membrane protein (NCBI) compare
b0439 lon -1.8 -5.0 DNA-binding ATP-dependent protease La (NCBI) compare
b1860 ruvB -1.7 -1.1 Holliday junction DNA helicase B (NCBI) compare
b3052 rfaE -1.7 -4.8 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1161 ycgX -1.6 -1.0 hypothetical protein (NCBI) compare
b3838 tatB -1.6 -6.3 sec-independent translocase (NCBI) compare
b1863 ruvC -1.6 -1.5 Holliday junction resolvase (NCBI) compare
b3613 yibP -1.6 -1.9 putative membrane protein (VIMSS) compare
b1709 btuD -1.5 -1.4 vitamin B12-transporter ATPase (NCBI) compare
b3405 ompR -1.5 -3.4 osmolarity response regulator (NCBI) compare
b3636 rpmG -1.5 -2.1 50S ribosomal protein L33 (NCBI) compare
b2504 yfgG -1.5 -1.7 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b0738 tolR -1.5 -1.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4179 vacB -1.5 -5.7 putative enzyme (VIMSS) compare
b3778 rep -1.5 -7.2 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2897 ygfY -1.4 -2.3 hypothetical protein (NCBI) compare
b3761 trpT -1.4 -1.7 tRNA-Trp (NCBI) compare
b3792 wzxE -1.4 -6.0 O-antigen translocase (NCBI) compare
b3484 yhhI -1.4 -3.4 predicted transposase (NCBI) compare
b4676 yoaK -1.4 -0.8 expressed protein (RefSeq) compare
b1575 dicB -1.4 -1.6 Qin prophage; cell division inhibition protein (NCBI) compare
b2620 smpB -1.4 -1.3 SsrA-binding protein (NCBI) compare
b0737 tolQ -1.3 -2.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3082 ygjM -1.3 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b2363 yfdT -1.3 -2.8 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b3620 rfaF -1.3 -4.4 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0890 ftsK -1.3 -2.1 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2934 cmtB -1.2 -0.8 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b3621 rfaC -1.2 -3.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1855 lpxM -1.1 -3.4 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2699 recA -1.1 -0.7 recombinase A (NCBI) compare
b4593 ymgI -1.1 -1.2 hypothetical protein (RefSeq) compare
b4146 yjeK -1.1 -1.4 predicted lysine aminomutase (NCBI) compare
b3860 dsbA -1.1 -5.6 periplasmic protein disulfide isomerase I (NCBI) compare
b4552 yrhC -1.1 -0.7 no description compare
b1159 mcrA -1.0 -0.7 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b3164 pnp -1.0 -2.3 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0222 lpcA -1.0 -1.9 phosphoheptose isomerase (NCBI) compare
b1025 ycdT -1.0 -1.3 predicted diguanylate cyclase (NCBI) compare
b1758 b1758 -1.0 -1.4 putative cytochrome oxidase (VIMSS) compare
b3619 rfaD -1.0 -2.4 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1293 sapB -1.0 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0688 pgm -1.0 -2.3 phosphoglucomutase (NCBI) compare
b3237 argR -1.0 -2.6 arginine repressor (NCBI) compare
b1977 asnT -1.0 -2.6 tRNA-Asn (NCBI) compare
b4370 leuQ -1.0 -1.6 tRNA-Leu (NCBI) compare
b0741 pal -1.0 -2.3 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0720 gltA -1.0 -3.8 citrate synthase (NCBI) compare
b3162 deaD -1.0 -3.1 inducible ATP-independent RNA helicase (VIMSS) compare
b1185 dsbB -0.9 -2.4 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b1558 cspF -0.9 -2.3 Qin prophage; cold shock protein (NCBI) compare
b3889 yiiE -0.9 -1.8 predicted transcriptional regulator (RefSeq) compare
b0200 gmhB -0.9 -0.9 hypothetical protein (NCBI) compare
b0560 nohB -0.9 -2.3 DLP12 prophage; DNA packaging protein (NCBI) compare
b1572 ydfB -0.9 -1.6 orf, hypothetical protein (VIMSS) compare
b0739 tolA -0.9 -2.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1175 minD -0.9 -2.9 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b4246 pyrL -0.9 -1.1 pyrBI operon leader peptide (NCBI) compare
b1257 yciE -0.9 -0.6 hypothetical protein (NCBI) compare
b3623 rfaK -0.9 -1.0 lipopolysaccharide core biosynthesis (NCBI) compare
b3836 b3836 -0.9 -2.3 orf, hypothetical protein (VIMSS) compare
b3811 xerC -0.9 -0.6 site-specific tyrosine recombinase XerC (NCBI) compare
b1874 cutC -0.9 -2.3 copper homeostasis protein (NCBI) compare
b2528 iscA -0.9 -0.9 iron-sulfur cluster assembly protein (NCBI) compare
b1553 ydfP -0.8 -0.8 Qin prophage; conserved protein (NCBI) compare
b0082 mraW -0.8 -2.1 S-adenosyl-methyltransferase (NCBI) compare
b4538 yoeF -0.8 -1.1 hypothetical protein (RefSeq) compare
b4042 dgkA -0.8 -1.1 diacylglycerol kinase (NCBI) compare
b1062 pyrC -0.8 -4.0 dihydroorotase (NCBI) compare
b2935 tktA -0.8 -0.9 transketolase 1, thiamin-binding (NCBI) compare
b1793 yoaF -0.8 -1.7 conserved outer membrane protein (NCBI) compare
b4157 yjeN -0.8 -3.8 hypothetical protein (NCBI) compare
b3726 pstA -0.8 -2.8 phosphate transporter subunit (NCBI) compare
b0728 sucC -0.8 -3.2 succinyl-CoA synthetase subunit beta (NCBI) compare
b0889 lrp -0.8 -2.4 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b4592 yccB -0.8 -0.7 hypothetical protein (RefSeq) compare
b0499 ylbH -0.8 -3.0 conserved protein, rhs-like (RefSeq) compare
b1058 yceO -0.7 -0.4 hypothetical protein (NCBI) compare
b1362 rzpR -0.7 -1.9 putative Rac prophage endopeptidase (VIMSS) compare
b1692 ydiB -0.7 -2.3 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b1505 ydeT -0.7 -0.7 hypothetical protein (RefSeq) compare
b1765 ydjA -0.7 -0.6 predicted oxidoreductase (NCBI) compare
b4011 yjaA -0.7 -2.4 hypothetical protein (NCBI) compare
b1671 ydhX -0.7 -1.8 predicted 4Fe-4S ferridoxin-type protein (RefSeq) compare
b4345 mcrC -0.7 -0.5 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI) compare
b0018 mokC -0.7 -1.1 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b0676 nagC -0.7 -3.9 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b4631 ykgQ -0.7 -0.7 no description compare
b2754 ygbF -0.7 -2.0 orf, hypothetical protein (VIMSS) compare
b0858 ybjO -0.7 -1.4 predicted inner membrane protein (NCBI) compare
b2314 dedD -0.7 -2.9 putative lipoprotein (VIMSS) compare
b3029 ygiN -0.7 -1.4 quinol monooxygenase (NCBI) compare
b0549 ybcO -0.7 -0.7 DLP12 prophage; predicted protein (NCBI) compare
b0865 ybjP -0.7 -2.3 predicted lipoprotein (NCBI) compare
b0340 cynS -0.7 -2.5 cyanate hydratase (NCBI) compare
b4426 isrA -0.7 -1.1 unknown RNA (NCBI) compare
b2325 yfcL -0.7 -2.0 hypothetical protein (NCBI) compare
b1850 eda -0.7 -1.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0729 sucD -0.6 -1.4 succinyl-CoA synthetase subunit alpha (NCBI) compare
b0049 apaH -0.6 -1.2 diadenosinetetraphosphatase (NCBI) compare
b1613 manA -0.6 -1.1 mannose-6-phosphate isomerase (VIMSS) compare
b3741 gidA -0.6 -1.7 glucose-inhibited division protein A (NCBI) compare
b1562 hokD -0.6 -1.6 Qin prophage; small toxic polypeptide (NCBI) compare
b0481 ybaK -0.6 -2.1 hypothetical protein (NCBI) compare
b2809 b2809 -0.6 -2.3 orf, hypothetical protein (VIMSS) compare
b3806 cyaA -0.6 -2.6 adenylate cyclase (NCBI) compare
b0080 fruR -0.6 -2.9 DNA-binding transcriptional dual regulator (NCBI) compare
b0611 rna -0.6 -2.6 ribonuclease I (NCBI) compare
b0964 yccT -0.6 -3.4 hypothetical protein (NCBI) compare
b2814 metZ -0.6 -0.9 tRNA-Met (NCBI) compare
b1351 racC -0.6 -0.4 Rac prophage; predicted protein (NCBI) compare
b0251 yafY -0.6 -1.6 CP4-6 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b0784 moaD -0.6 -1.6 molybdopterin synthase, small subunit (NCBI) compare
b1355 b1355 -0.6 -2.2 orf, hypothetical protein (VIMSS) compare
b1730 ydjO -0.6 -0.6 predicted protein (RefSeq) compare
b2331 yfcN -0.6 -2.3 hypothetical protein (NCBI) compare
b3389 aroB -0.6 -3.4 3-dehydroquinate synthase (NCBI) compare
b3257 yhdT -0.6 -2.1 conserved inner membrane protein (NCBI) compare
b1143 ymfI -0.6 -1.4 orf, hypothetical protein (VIMSS) compare
b4191 ulaR -0.6 -1.4 DNA-binding transcriptional dual regulator (NCBI) compare
b1685 ydiH -0.6 -1.0 predicted protein (RefSeq) compare
b3601 mtlR -0.6 -3.2 DNA-binding repressor (NCBI) compare
b1368 ynaA -0.6 -1.7 Rac prophage; predicted tail protein (RefSeq) compare
b1273 yciN -0.6 -1.1 hypothetical protein (NCBI) compare
b2376 ypdI -0.6 -1.7 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b3024 ygiW -0.6 -2.7 hypothetical protein (NCBI) compare
b0953 rmf -0.6 -1.1 ribosome modulation factor (NCBI) compare
b2576 srmB -0.6 -1.5 ATP-dependent RNA helicase (NCBI) compare
b0619 citA -0.6 -3.2 sensory histidine kinase in two-component regulatory system with citB (NCBI) compare
b4535 yniD -0.6 -0.7 predicted protein (RefSeq) compare
b2274 yfbO -0.6 -2.5 predicted protein (RefSeq) compare
b3871 bipA -0.6 -3.9 GTP-binding protein (NCBI) compare
b0730 mngR -0.6 -0.9 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1796 yoaG -0.6 -1.8 hypothetical protein (NCBI) compare
b4702 mgtL -0.6 -0.8 regulatory leader peptide for mgtA (NCBI) compare
b2900 yqfB -0.6 -1.8 hypothetical protein (NCBI) compare
b3026 qseC -0.6 -1.3 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b2506 yfgI -0.6 -1.3 hypothetical protein (NCBI) compare
b3281 aroE -0.6 -4.3 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1179 ycgL -0.6 -1.3 conserved protein (NCBI) compare
b1693 aroD -0.5 -2.1 3-dehydroquinate dehydratase (NCBI) compare
b0368 tauD -0.5 -2.6 taurine dioxygenase (NCBI) compare
b1153 ymfQ -0.5 -2.8 e14 prophage; conserved protein (NCBI) compare
b1840 yebZ -0.5 -2.6 predicted inner membrane protein (NCBI) compare
b2024 hisA -0.5 -1.2 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b3426 glpD -0.5 -1.3 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1182 hlyE -0.5 -0.3 hemolysin E (VIMSS) compare
b1041 csgB -0.5 -2.7 curlin nucleator protein, minor subunit in curli complex (NCBI) compare
b0854 potF -0.5 -2.5 putrescine transporter subunit: periplasmic-binding component of ABC superfamily (NCBI) compare
b0817 mntR -0.5 -1.6 DNA-binding transcriptional regulator of mntH (NCBI) compare
b2318 truA -0.5 -1.2 tRNA pseudouridine synthase A (NCBI) compare
b0197 metQ -0.5 -2.8 DL-methionine transporter subunit (NCBI) compare
b4533 ynfO -0.5 -1.6 Qin prophage; predicted protein (NCBI) compare
b3933 ftsN -0.5 -3.7 essential cell division protein (NCBI) compare
b0705 ybfL -0.5 -0.3 putative receptor protein (VIMSS) compare
b4647 mokA -0.5 -0.3 no description compare
b2055 wcaE -0.5 -0.3 predicted glycosyl transferase (NCBI) compare
b0881 clpS -0.5 -1.0 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b0920 ycbC -0.5 -1.6 conserved inner membrane protein (NCBI) compare
b1347 ydaC -0.5 -0.3 Rac prophage; predicted protein (NCBI) compare
b4503 yafF -0.5 -0.3 no description compare
b1251 yciI -0.5 -1.7 orf, hypothetical protein (VIMSS) compare
b1129 phoQ -0.5 -0.9 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1551 b1551 -0.5 -0.3 orf, hypothetical protein (VIMSS) compare
b4414 tff -0.5 -1.0 unknown RNA (NCBI) compare
b2688 gshA -0.5 -2.3 glutamate--cysteine ligase (NCBI) compare
b0521 ybcF -0.5 -2.2 predicted carbamate kinase (NCBI) compare
b0219 yafV -0.5 -2.0 predicted C-N hydrolase family amidase, NAD(P)-binding (NCBI) compare
b3250 mreC -0.5 -0.9 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b1382 ynbE -0.5 -0.9 predicted lipoprotein (NCBI) compare
b1291 sapD -0.5 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1989 asnV -0.5 -1.4 tRNA-Asn (NCBI) compare
b3999 yjaG -0.5 -2.1 hypothetical protein (NCBI) compare
b3652 recG -0.5 -3.1 ATP-dependent DNA helicase (NCBI) compare
b3169 nusA -0.5 -1.0 transcription elongation factor NusA (NCBI) compare
b1951 rcsA -0.5 -0.7 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b0630 lipB -0.5 -0.3 protein of lipoate biosynthesis (VIMSS) compare
b0880 cspD -0.5 -1.5 cold shock protein homolog (NCBI) compare
b1566 flxA -0.5 -1.8 Qin prophage; predicted protein (NCBI) compare
b1171 b1171 -0.5 -0.8 orf, hypothetical protein (VIMSS) compare
b2946 yggJ -0.5 -2.5 orf, hypothetical protein (VIMSS) compare
b3198 kdsC -0.5 -1.8 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b1358 ydaT -0.5 -0.6 Rac prophage; predicted protein (NCBI) compare
b4413 sokC -0.5 -0.9 regulatory antisense RNA (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in no-phage experiments

For no-phage No-Phage across organisms