Experiment set6IT022 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

6H2_phage 10 MOI; agar plate assay

200 most important genes:

  gene name fitness t score description  
GFF2347 -8.8 -5.0 Hydrogen peroxide-inducible genes activator compare
GFF2475 -7.0 -1.9 Ribonuclease III (EC 3.1.26.3) compare
GFF384 -6.3 -2.8 UDP-glucose:(glucosyl)lipopolysaccharide alpha-1,3-glucosyltransferase WaaO (EC 2.4.1.-) compare
GFF603 -6.1 -3.0 NfuA Fe-S protein maturation compare
GFF4655 -6.1 -2.2 18K peptidoglycan-associated outer membrane lipoprotein; Peptidoglycan-associated lipoprotein precursor; Outer membrane protein P6; OmpA/MotB precursor compare
GFF387 -6.1 -2.8 Lipopolysaccharide core biosynthesis protein RfaZ compare
GFF121 -6.0 -2.7 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF342 -5.9 -1.0 FIG01046502: hypothetical protein compare
GFF2808 -5.8 -7.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
GFF824 -5.6 -2.5 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF873 -5.6 -0.9 hypothetical protein compare
GFF1934 -5.4 -3.9 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
GFF1634 -5.3 -2.4 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF388 -5.3 -10.9 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase (EC 2.4.1.56) compare
GFF2392 -5.3 -1.2 Peptide deformylase (EC 3.5.1.88) compare
GFF267 -5.3 -6.5 Transcriptional activator RfaH compare
GFF4652 -5.3 -2.2 Tol biopolymer transport system, TolR protein compare
GFF1920 -5.2 -0.8 hypothetical protein compare
GFF1334 -5.2 -0.8 Uncharacterized protein YohL compare
GFF3890 -4.9 -1.9 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF2991 -4.8 -2.2 Tyrosine recombinase XerD compare
GFF1716 -4.7 -7.7 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF391 -4.6 -1.5 ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) compare
GFF20 -4.6 -5.6 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) compare
GFF4653 -4.6 -1.6 TolA protein compare
GFF2216 -4.6 -9.5 DNA polymerase I (EC 2.7.7.7) compare
GFF4639 -4.6 -1.6 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF122 -4.5 -8.5 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF4654 -4.5 -3.5 tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins compare
GFF236 -4.4 -0.7 FIG00545237: hypothetical protein compare
GFF2784 -4.3 -2.9 GTP-binding and nucleic acid-binding protein YchF compare
GFF2690 -4.3 -1.7 Peptide transport system permease protein SapC compare
GFF2389 -4.2 -1.5 Trk system potassium uptake protein TrkA compare
GFF4601 -4.2 -7.2 Phosphoglucomutase (EC 5.4.2.2) compare
GFF2276 -4.2 -1.3 Manganese superoxide dismutase (EC 1.15.1.1) compare
GFF635 -4.1 -4.6 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF389 -3.9 -2.3 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF4353 -3.9 -3.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF2104 -3.9 -2.4 ATP-dependent RNA helicase SrmB compare
GFF3166 -3.9 -3.3 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase compare
GFF2515 -3.8 -0.9 putative outer membrane protein compare
GFF4600 -3.8 -3.5 SeqA protein, negative modulator of initiation of replication compare
GFF4355 -3.8 -0.9 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF1750 -3.8 -3.2 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF2213 -3.8 -5.8 Periplasmic thiol:disulfide interchange protein DsbA compare
GFF2946 -3.8 -3.4 RNA polymerase sigma-54 factor RpoN compare
GFF633 -3.8 -4.2 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF55 -3.6 -9.4 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF4354 -3.6 -2.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF1090 -3.5 -3.7 Chaperone protein DnaJ compare
GFF1076 -3.5 -2.6 Aerobic respiration control protein arcA compare
GFF1499 -3.5 -2.9 Ribosome-binding factor A compare
GFF4027 -3.4 -1.3 Flagellar biosynthesis protein FliS compare
GFF392 -3.4 -1.5 ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) compare
GFF3888 -3.4 -3.2 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF1303 -3.4 -1.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF192 -3.3 -6.8 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF276 -3.2 -5.8 Potassium uptake protein TrkH compare
GFF3772 -3.2 -1.6 1-phosphofructokinase (EC 2.7.1.56) compare
GFF2478 -3.2 -1.1 leucine-rich repeat protein compare
GFF1921 -3.2 -1.7 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-) compare
GFF1571 -3.1 -0.7 FIG00638334: hypothetical protein compare
GFF2881 -3.1 -7.3 WzxE protein compare
GFF4596 -3.1 -1.9 Ferric uptake regulation protein FUR compare
GFF2173 -3.1 -3.9 Chromosomal replication initiator protein DnaA compare
GFF2689 -3.1 -2.4 Peptide transport system permease protein SapB compare
GFF1032 -3.0 -0.7 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF3712 -3.0 -2.8 Cyclic AMP receptor protein compare
GFF3862 -2.9 -4.9 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF630 -2.9 -6.4 3-dehydroquinate synthase (EC 4.2.3.4) compare
GFF2045 -2.9 -1.7 hypothetical protein compare
GFF3548 -2.9 -4.3 3-dehydroquinate dehydratase I (EC 4.2.1.10) compare
GFF2031 -2.9 -0.9 FIG01046611: hypothetical protein compare
GFF390 -2.9 -2.1 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
GFF2047 -2.8 -6.9 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
GFF3320 -2.8 -1.4 Transcriptional regulator CsgD for 2nd curli operon compare
GFF2348 -2.7 -4.2 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
GFF1256 -2.7 -3.3 Chromosome (plasmid) partitioning protein ParA compare
GFF1699 -2.7 -1.8 BarA-associated response regulator UvrY (= GacA = SirA) compare
GFF4722 -2.7 -1.4 [NiFe] hydrogenase metallocenter assembly protein HypC compare
GFF146 -2.7 -2.4 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
GFF1312 -2.7 -2.6 'Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-)' transl_table=11 compare
GFF2409 -2.6 -6.3 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
GFF4636 -2.6 -3.1 Succinate dehydrogenase hydrophobic membrane anchor protein compare
GFF3528 -2.6 -2.1 Integration host factor alpha subunit compare
GFF4182 -2.5 -5.5 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) compare
GFF115 -2.5 -2.6 Aconitate hydratase 2 (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) compare
GFF2434 -2.4 -0.7 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF1304 -2.4 -1.7 FIG004136: Prepilin peptidase dependent protein C precursor compare
GFF1901 -2.4 -4.5 Phosphate acetyltransferase (EC 2.3.1.8) compare
GFF2220 -2.4 -6.5 Nitrogen regulation protein NR(I) compare
GFF2692 -2.4 -3.8 Peptide transport system ATP-binding protein SapF compare
GFF4288 -2.4 -5.2 AroM protein compare
GFF2221 -2.4 -7.1 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
GFF2863 -2.4 -1.0 FIG074102: hypothetical protein compare
GFF876 -2.4 -10.4 UPF0131 protein YtfP compare
GFF629 -2.3 -1.3 Shikimate kinase I (EC 2.7.1.71) compare
GFF3632 -2.3 -1.5 Transcriptional regulator SlyA compare
GFF2431 -2.3 -2.2 Chaperone protein HscA compare
GFF825 -2.3 -2.3 RNA-binding protein Hfq compare
GFF2477 -2.2 -4.5 Translation elongation factor LepA compare
GFF4145 -2.2 -0.8 hypothetical protein compare
GFF381 -2.2 -5.7 Lipopolysaccharide core biosynthesis protein WaaP (EC 2.7.-.-), heptosyl-I-kinase compare
GFF2994 -2.1 -1.2 YgfY COG2938 compare
GFF2397 -2.1 -4.9 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
GFF188 -2.1 -5.8 Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) compare
GFF2160 -2.1 -1.7 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF2119 -2.1 -1.1 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
GFF3463 -2.0 -1.0 FIG00638667: hypothetical protein compare
GFF4637 -2.0 -8.6 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) compare
GFF3667 -2.0 -1.1 Cytidylate kinase (EC 2.7.4.25) compare
GFF3461 -2.0 -0.8 hypothetical protein compare
GFF632 -2.0 -5.8 Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) compare
GFF4772 -2.0 -0.9 hypothetical protein compare
GFF355 -2.0 -1.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF4745 -2.0 -0.9 secretion chaparone compare
GFF4621 -2.0 -1.6 putative inner membrane protein compare
GFF1900 -2.0 -5.6 Acetate kinase (EC 2.7.2.1) compare
GFF2992 -1.9 -5.5 Flavodoxin 2 compare
GFF883 -1.9 -5.6 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
GFF4822 -1.9 -2.0 Queuosine biosynthesis QueD, PTPS-I compare
GFF1888 -1.9 -1.5 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
GFF2147 -1.8 -1.3 probable exported protein YPO3518 compare
GFF828 -1.8 -2.8 HflC protein compare
GFF2433 -1.8 -2.9 Iron binding protein IscA for iron-sulfur cluster assembly compare
GFF2664 -1.8 -1.9 FIG01200701: possible membrane protein compare
GFF2148 -1.8 -1.9 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
GFF1881 -1.8 -5.9 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
GFF2049 -1.8 -0.8 FIG01045978: hypothetical protein compare
GFF3196 -1.8 -0.9 Inner membrane protein YqjE compare
GFF3149 -1.7 -7.2 Type I secretion outer membrane protein, TolC precursor compare
GFF3722 -1.7 -0.9 Putative cytoplasmic protein ,probably associated with Glutathione-regulated potassium-efflux compare
GFF2415 -1.7 -2.1 Nucleoside diphosphate kinase (EC 2.7.4.6) compare
GFF4522 -1.7 -1.1 Regulator of nucleoside diphosphate kinase compare
GFF2592 -1.6 -1.5 secreted effector protein compare
GFF230 -1.6 -6.8 Adenylate cyclase (EC 4.6.1.1) compare
GFF380 -1.6 -3.8 UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG (EC 2.4.1.-) compare
GFF2051 -1.6 -4.4 Predicted transcriptional regulator of pyridoxine metabolism compare
GFF2948 -1.6 -2.4 PTS system nitrogen-specific IIA component, PtsN compare
GFF3453 -1.6 -1.4 Periplasmic chorismate mutase I precursor (EC 5.4.99.5) compare
GFF829 -1.6 -0.7 Putative inner membrane protein YjeT (clustered with HflC) compare
GFF87 -1.6 -1.2 C4-type zinc finger protein, DksA/TraR family compare
GFF3544 -1.6 -0.8 Electron transfer flavoprotein, beta subunit compare
GFF652 -1.6 -4.3 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) / UDP-glucose 4-epimerase (EC 5.1.3.2) compare
GFF1597 -1.6 -8.3 Glutamate--cysteine ligase (EC 6.3.2.2) compare
GFF4158 -1.6 -1.0 tmRNA-binding protein SmpB compare
GFF916 -1.6 -1.1 RelB/StbD replicon stabilization protein (antitoxin to RelE/StbE) compare
GFF2773 -1.6 -2.1 Protein-N(5)-glutamine methyltransferase PrmC, methylates polypeptide chain release factors RF1 and RF2 compare
GFF3248 -1.6 -1.9 Outer membrane protein A precursor compare
GFF573 -1.6 -0.8 FIG01046423: hypothetical protein compare
GFF1037 -1.6 -1.6 Osmotically inducible protein OsmY compare
GFF3049 -1.5 -3.1 Glutathione synthetase (EC 6.3.2.3) compare
GFF4638 -1.5 -2.6 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) compare
GFF1891 -1.5 -1.8 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
GFF4513 -1.5 -2.0 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) compare
GFF2564 -1.5 -1.7 Gfa-like protein compare
GFF401 -1.5 -1.8 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
GFF2194 -1.5 -1.2 FIG01046050: hypothetical protein compare
GFF3555 -1.5 -0.6 1,4-dihydroxy-2-naphthoyl-CoA hydrolase (EC 3.1.2.28) in menaquinone biosynthesis compare
GFF1939 -1.5 -2.0 FIG00643583: hypothetical protein compare
GFF2640 -1.5 -0.8 probable lipoprotein YPO2331 compare
GFF1953 -1.5 -1.7 Phosphohistidine phosphatase SixA compare
GFF2882 -1.5 -4.8 Lipopolysaccharide biosynthesis protein RffA compare
GFF2314 -1.5 -2.0 ATP-dependent protease HslV (EC 3.4.25.-) compare
GFF2867 -1.4 -1.0 hypothetical protein compare
GFF1884 -1.4 -0.9 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) compare
GFF1497 -1.4 -1.3 Transcription termination protein NusA compare
GFF4642 -1.4 -0.9 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
GFF4270 -1.4 -0.6 FIG00637869: hypothetical protein compare
GFF333 -1.4 -1.4 hypothetical protein compare
GFF4342 -1.4 -3.8 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
GFF648 -1.4 -2.6 Phosphoglycerate mutase (EC 5.4.2.1) compare
GFF1553 -1.4 -0.7 FIG01046564: hypothetical protein compare
GFF2223 -1.4 -3.2 GTP-binding protein TypA/BipA compare
GFF4641 -1.4 -1.3 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare
GFF1890 -1.4 -5.7 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
GFF3702 -1.4 -1.3 hypothetical protein compare
GFF2552 -1.4 -2.9 Putative secreted protein compare
GFF454 -1.4 -0.8 Cold shock protein CspA compare
GFF3830 -1.4 -0.5 Uncharacterized protein YehA precursor compare
GFF3599 -1.3 -1.9 Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) compare
GFF2468 -1.3 -0.7 Putative transmembrane transport protein compare
GFF2832 -1.3 -1.2 PTS system, mannose-specific IIC component (EC 2.7.1.69) compare
GFF4304 -1.3 -2.7 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
GFF109 -1.3 -1.6 DeoR family transcriptional regulator probably related to glycerate, glycolaldehyde metabolism compare
GFF1937 -1.3 -2.9 Cell division protein compare
GFF1883 -1.3 -3.6 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) compare
GFF631 -1.3 -2.9 DamX, an inner membrane protein involved in bile resistance compare
GFF3533 -1.3 -1.0 FIG00638687: hypothetical protein compare
GFF1880 -1.3 -4.4 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
GFF1828 -1.3 -3.7 Thiamin biosynthesis lipoprotein ApbE compare
GFF242 -1.3 -1.5 Magnesium and cobalt transport protein CorA compare
GFF619 -1.3 -3.2 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
GFF2989 -1.3 -3.5 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF269 -1.3 -2.4 NAD(P)H-flavin reductase (EC 1.5.1.29) (EC 1.16.1.3) compare
GFF2737 -1.3 -1.0 YciL protein compare
GFF1886 -1.2 -5.7 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
GFF3747 -1.2 -2.1 FIG001881: hydrolase of alkaline phosphatase superfamily compare
GFF513 -1.2 -6.6 Glutathione reductase (EC 1.8.1.7) compare
GFF587 -1.2 -1.9 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in phage experiments

For phage 6H2_phage across organisms