Experiment set6IT002 for Klebsiella michiganensis M5al

Compare to:

L-Histidine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS21465 -8.3 -5.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01210 -8.2 -5.2 tyrosine recombinase XerC compare
BWI76_RS04470 -7.8 -9.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS22755 -7.6 -5.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS20350 -7.4 -8.8 amidophosphoribosyltransferase compare
BWI76_RS00855 -7.4 -7.2 argininosuccinate lyase compare
BWI76_RS05835 -7.3 -5.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS00850 -7.2 -8.4 acetylglutamate kinase compare
BWI76_RS04675 -7.2 -7.0 3-isopropylmalate dehydrogenase compare
BWI76_RS11965 -7.0 -5.0 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00385 -7.0 -9.7 nitrogen assimilation regulatory protein compare
BWI76_RS05840 -7.0 -4.8 glutamate 5-kinase compare
BWI76_RS00845 -6.9 -9.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04685 -6.7 -9.2 putative leucine operon leader peptide compare
BWI76_RS23220 -6.7 -9.2 amino-acid N-acetyltransferase compare
BWI76_RS20895 -6.5 -6.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS09755 -6.5 -6.5 phosphoserine transaminase compare
BWI76_RS04250 -6.4 -9.5 homoserine kinase compare
BWI76_RS00980 -6.3 -12.1 PLP-dependent threonine dehydratase compare
BWI76_RS23360 -6.3 -4.3 diaminopimelate decarboxylase compare
BWI76_RS00990 -6.2 -9.2 ketol-acid reductoisomerase compare
BWI76_RS20355 -6.2 -3.7 colicin V production protein compare
BWI76_RS02995 -6.1 -8.4 aspartate carbamoyltransferase compare
BWI76_RS01610 -6.1 -7.7 phosphoribosylamine--glycine ligase compare
BWI76_RS05015 -6.1 -4.2 transcriptional regulator compare
BWI76_RS04665 -6.1 -21.8 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04255 -6.0 -10.9 threonine synthase compare
BWI76_RS26085 -6.0 -3.8 3-dehydroquinate synthase compare
BWI76_RS24285 -5.9 -10.6 cystathionine beta-lyase compare
BWI76_RS00785 -5.8 -8.8 cystathionine gamma-synthase compare
BWI76_RS04245 -5.7 -15.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11860 -5.7 -11.0 anthranilate synthase component I compare
BWI76_RS11855 -5.7 -8.5 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04670 -5.7 -10.7 3-isopropylmalate dehydratase large subunit compare
BWI76_RS11850 -5.7 -10.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS21475 -5.7 -7.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS27385 -5.7 -7.8 orotate phosphoribosyltransferase compare
BWI76_RS02735 -5.6 -5.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS04160 -5.5 -5.3 phosphoserine phosphatase compare
BWI76_RS04465 -5.4 -6.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS07070 -5.4 -6.8 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS25645 -5.4 -8.2 shikimate dehydrogenase compare
BWI76_RS20965 -5.3 -5.4 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04680 -5.2 -11.5 2-isopropylmalate synthase compare
BWI76_RS00965 -5.2 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS01655 -5.2 -10.5 homoserine O-succinyltransferase compare
BWI76_RS11840 -5.2 -5.2 tryptophan synthase subunit alpha compare
BWI76_RS00400 -5.2 -3.2 glutamine synthetase compare
BWI76_RS25315 -5.1 -10.0 glutamate synthase large subunit compare
BWI76_RS03010 -5.1 -11.3 ornithine carbamoyltransferase compare
BWI76_RS09910 -5.1 -17.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS25320 -5.0 -12.4 glutamate synthase compare
BWI76_RS08720 -5.0 -3.3 imidazolonepropionase compare
BWI76_RS22765 -5.0 -11.6 sulfite reductase subunit alpha compare
BWI76_RS25115 -4.9 -6.5 argininosuccinate synthase compare
BWI76_RS01350 -4.8 -1.8 NAD(P)H-flavin reductase compare
BWI76_RS08740 -4.8 -9.8 Histidine ammonia-lyase (EC 4.3.1.3) (from data) conserved
BWI76_RS08180 -4.7 -7.1 asparagine synthase B compare
BWI76_RS23920 -4.7 -4.7 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS11845 -4.7 -2.6 tryptophan synthase subunit beta compare
BWI76_RS00975 -4.6 -9.2 dihydroxy-acid dehydratase compare
BWI76_RS01615 -4.6 -8.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS21265 -4.6 -10.9 phosphoribosylformylglycinamidine synthase compare
BWI76_RS22760 -4.5 -8.6 sulfite reductase subunit beta compare
BWI76_RS00390 -4.5 -6.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS05200 -4.5 -3.1 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22805 -4.5 -10.2 GTP diphosphokinase compare
BWI76_RS23365 -4.4 -9.8 LysR family transcriptional regulator compare
BWI76_RS09660 -4.2 -2.9 DNA translocase FtsK compare
BWI76_RS04240 -4.2 -2.7 thr operon leader peptide compare
BWI76_RS09760 -4.1 -2.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS08735 -4.1 -6.6 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
BWI76_RS08725 -4.0 -7.1 Formiminoglutamase (EC 3.5.3.8) (from data) conserved
BWI76_RS27390 -4.0 -3.3 ribonuclease PH compare
BWI76_RS07065 -4.0 -10.9 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS03665 -4.0 -2.7 ABC transporter ATP-binding protein compare
BWI76_RS01200 -4.0 -2.7 diaminopimelate epimerase compare
BWI76_RS10990 -4.0 -4.9 dihydroorotase compare
BWI76_RS20380 -4.0 -2.1 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS23230 -3.9 -4.7 exodeoxyribonuclease V subunit beta compare
BWI76_RS23240 -3.9 -4.7 exonuclease V subunit gamma compare
BWI76_RS27440 -3.9 -5.2 DNA helicase RecG compare
BWI76_RS04645 -3.9 -4.6 3-dehydroquinase compare
BWI76_RS17720 -3.8 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS25065 -3.7 -5.1 polyribonucleotide nucleotidyltransferase compare
BWI76_RS12090 -3.7 -1.7 HNH endonuclease compare
BWI76_RS00805 -3.7 -5.7 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18630 -3.2 -9.6 nitrogen assimilation transcriptional regulator conserved
BWI76_RS26055 -3.0 -9.0 siroheme synthase compare
BWI76_RS20435 -3.0 -1.4 chorismate synthase compare
BWI76_RS22690 -2.9 -4.3 adenylyl-sulfate kinase compare
BWI76_RS23265 -2.9 -5.4 hypothetical protein compare
BWI76_RS02530 -2.8 -4.5 tRNA dimethylallyltransferase compare
BWI76_RS08385 -2.7 -4.3 citrate (Si)-synthase compare
BWI76_RS09655 -2.6 -4.5 leucine-responsive regulatory protein compare
BWI76_RS00985 -2.6 -6.7 transcriptional regulator IlvY compare
BWI76_RS00840 -2.6 -12.0 acetylornithine deacetylase compare
BWI76_RS20640 -2.5 -6.8 cysteine synthase A compare
BWI76_RS09645 -2.5 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS25070 -2.5 -2.0 hypothetical protein compare
BWI76_RS21910 -2.4 -6.4 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS26570 -2.3 -3.9 anion permease compare
BWI76_RS16965 -2.2 -6.2 murein lipoprotein compare
BWI76_RS09650 -2.2 -6.6 hypothetical protein compare
BWI76_RS00940 -2.1 -7.7 transcriptional regulator HdfR compare
BWI76_RS00345 -2.1 -4.7 protein disulfide oxidoreductase DsbA compare
BWI76_RS05450 -2.1 -2.0 ribonuclease HI compare
BWI76_RS09970 -2.1 -3.1 porin OmpA compare
BWI76_RS21480 -2.1 -7.1 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS21370 -2.1 -3.1 ATP-dependent RNA helicase SrmB compare
BWI76_RS08525 -2.0 -2.4 colicin transporter compare
BWI76_RS17980 -2.0 -3.7 RNA chaperone ProQ compare
BWI76_RS01800 -1.9 -4.5 glucose-6-phosphate isomerase compare
BWI76_RS02990 -1.9 -4.5 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS08535 -1.9 -2.0 translocation protein TolB compare
BWI76_RS21070 -1.8 -2.1 outer membrane protein assembly factor BamB compare
BWI76_RS21905 -1.8 -6.2 class II aldolase compare
BWI76_RS15835 -1.8 -1.2 hypothetical protein compare
BWI76_RS05075 -1.8 -1.5 type II secretion system protein GspG compare
BWI76_RS21900 -1.8 -4.9 amino acid ABC transporter permease/ATP-binding protein compare
BWI76_RS23480 -1.7 -9.8 EAL domain-containing protein compare
BWI76_RS06535 -1.7 -3.7 endopeptidase La compare
BWI76_RS14320 -1.7 -2.5 hypothetical protein compare
BWI76_RS26075 -1.7 -4.0 DNA adenine methylase compare
BWI76_RS17290 -1.7 -3.1 formyltetrahydrofolate deformylase compare
BWI76_RS00240 -1.6 -2.3 FMN-binding protein MioC compare
BWI76_RS00960 -1.6 -5.1 acetolactate synthase 2 catalytic subunit compare
BWI76_RS20995 -1.6 -4.8 RNA degradosome polyphosphate kinase compare
BWI76_RS27430 -1.5 -0.9 (p)ppGpp synthetase compare
BWI76_RS08395 -1.5 -2.5 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS25335 -1.5 -2.3 stringent starvation protein A compare
BWI76_RS02180 -1.5 -1.5 hypothetical protein compare
BWI76_RS20915 -1.5 -7.0 peroxiredoxin compare
BWI76_RS26460 -1.5 -5.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS16935 -1.4 -1.7 shikimate dehydrogenase compare
BWI76_RS00180 -1.4 -1.9 F0F1 ATP synthase subunit epsilon compare
BWI76_RS15825 -1.4 -1.3 hypothetical protein compare
BWI76_RS06495 -1.4 -7.9 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS20440 -1.4 -1.5 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS24075 -1.4 -3.6 glutathione synthase compare
BWI76_RS08500 -1.3 -2.5 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS09030 -1.3 -6.8 transpeptidase compare
BWI76_RS19705 -1.3 -3.7 kinase compare
BWI76_RS06525 -1.3 -5.0 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS25425 -1.3 -1.8 arginine repressor compare
BWI76_RS19010 -1.3 -2.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS10290 -1.2 -3.3 transcriptional regulator compare
BWI76_RS15840 -1.2 -2.6 prophage protein compare
BWI76_RS04270 -1.2 -3.8 transaldolase compare
BWI76_RS06340 -1.2 -1.0 hypothetical protein compare
BWI76_RS25870 -1.2 -1.8 elongation factor Tu compare
BWI76_RS13560 -1.2 -1.2 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS22120 -1.2 -3.3 glutamate--cysteine ligase compare
BWI76_RS17975 -1.2 -4.3 tail-specific protease compare
BWI76_RS15830 -1.2 -2.0 hypothetical protein compare
BWI76_RS00140 -1.2 -0.9 phosphate transport system regulator PhoU compare
BWI76_RS03660 -1.2 -2.9 hypothetical protein compare
BWI76_RS21895 -1.1 -3.6 amino acid ABC transport system periplasmic amino acid-binding component compare
BWI76_RS08495 -1.1 -3.9 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS14625 -1.1 -1.2 protein TolA compare
BWI76_RS21310 -1.1 -1.1 DNA repair protein RecO compare
BWI76_RS21980 -1.1 -2.2 hypothetical protein compare
BWI76_RS26440 -1.1 -1.5 hypothetical protein compare
BWI76_RS00380 -1.1 -5.7 oxygen-independent coproporphyrinogen III oxidase compare
BWI76_RS15990 -1.1 -5.6 serine protease compare
BWI76_RS14915 -1.1 -2.2 hypothetical protein compare
BWI76_RS04305 -1.1 -1.2 molecular chaperone DnaJ compare
BWI76_RS06490 -1.1 -4.1 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS17530 -1.1 -2.3 hypothetical protein compare
BWI76_RS16235 -1.1 -3.0 membrane protein compare
BWI76_RS19685 -1.1 -4.6 lysine transporter compare
BWI76_RS04715 -1.1 -2.1 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS27425 -1.1 -1.1 DNA-directed RNA polymerase subunit omega compare
BWI76_RS11835 -1.1 -1.6 putative regulatory protein MarR compare
BWI76_RS27435 -1.0 -3.4 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BWI76_RS16675 -1.0 -1.7 ABC transporter compare
BWI76_RS13245 -1.0 -1.6 DNA-damage-inducible protein I compare
BWI76_RS07185 -1.0 -1.3 hypothetical protein compare
BWI76_RS14650 -1.0 -2.2 helix-turn-helix transcriptional regulator compare
BWI76_RS06485 -1.0 -2.4 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS22700 -1.0 -4.8 sulfate adenylyltransferase subunit 2 compare
BWI76_RS26455 -1.0 -3.8 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS06765 -1.0 -2.4 transcriptional regulator compare
BWI76_RS10935 -1.0 -2.6 glucan biosynthesis glucosyltransferase H compare
BWI76_RS05120 -1.0 -5.2 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS10930 -1.0 -4.4 glucan biosynthesis protein G compare
BWI76_RS20650 -1.0 -1.6 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS09635 -1.0 -1.5 amino acid ABC transporter ATP-binding protein compare
BWI76_RS16335 -1.0 -1.3 division septum protein Blr compare
BWI76_RS01890 -1.0 -2.8 transcriptional regulator Zur compare
BWI76_RS16895 -1.0 -1.6 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS19375 -1.0 -1.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS12335 -1.0 -3.4 hypothetical protein compare
BWI76_RS16120 -1.0 -2.1 4-carboxymuconolactone decarboxylase compare
BWI76_RS26775 -0.9 -2.8 endo-1,4-D-glucanase compare
BWI76_RS21235 -0.9 -1.1 hypothetical protein compare
BWI76_RS11700 -0.9 -1.3 hypothetical protein compare
BWI76_RS14305 -0.9 -2.3 metallophosphoesterase compare
BWI76_RS17195 -0.9 -2.1 hypothetical protein compare
BWI76_RS14770 -0.9 -1.2 PTS IIA 2 domain protein compare


Specific Phenotypes

For 8 genes in this experiment

For nitrogen source L-Histidine in Klebsiella michiganensis M5al

For nitrogen source L-Histidine across organisms