Experiment set5IT046 for Klebsiella michiganensis M5al

Compare to:

Sodium L-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS24575 +1.4 1.8 hypothetical protein compare
BWI76_RS20900 +1.3 1.6 outer membrane protein assembly factor BamC compare
BWI76_RS19870 +1.2 4.3 malate:quinone oxidoreductase compare
BWI76_RS05235 +1.1 1.9 hypothetical protein compare
BWI76_RS18410 +1.1 3.2 drug/metabolite exporter YedA compare
BWI76_RS19770 +1.1 1.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS08275 +1.1 2.0 LexA regulated protein compare
BWI76_RS00140 +1.0 1.7 phosphate transport system regulator PhoU compare
BWI76_RS15015 +1.0 1.7 DUF2132 domain-containing protein compare
BWI76_RS23340 +1.0 2.7 transcriptional regulator compare
BWI76_RS23125 +1.0 1.8 propanediol dehydratase small subunit compare
BWI76_RS16015 +1.0 2.7 pheromone autoinducer 2 transporter compare
BWI76_RS18770 +0.9 1.2 DNA gyrase inhibitor compare
BWI76_RS00740 +0.9 3.8 ribonuclease E activity regulator RraA compare
BWI76_RS15940 +0.9 2.5 DMSO reductase maturation protein DsmD compare
BWI76_RS14390 +0.9 1.2 hypothetical protein compare
BWI76_RS17530 +0.9 2.1 hypothetical protein compare
BWI76_RS01995 +0.9 1.2 AraC family transcriptional regulator compare
BWI76_RS24270 +0.9 1.8 membrane protein compare
BWI76_RS00715 +0.9 1.9 two-component sensor histidine kinase compare
BWI76_RS24080 +0.9 2.1 DUF179 domain-containing protein compare
BWI76_RS10435 +0.9 3.0 suppressor for copper-sensitivity C compare
BWI76_RS07860 +0.9 3.4 cytosine permease compare
BWI76_RS04985 +0.9 3.7 aspartate 1-decarboxylase compare
BWI76_RS03515 +0.9 1.8 hypothetical protein compare
BWI76_RS13250 +0.8 1.2 cytochrome b561 compare
BWI76_RS17975 +0.8 2.7 tail-specific protease compare
BWI76_RS21245 +0.8 1.4 nitrogen regulatory protein P-II compare
BWI76_RS20560 +0.8 2.3 hypothetical protein compare
BWI76_RS06330 +0.8 2.1 DNA-binding transcriptional regulator compare
BWI76_RS22640 +0.8 1.2 hypothetical protein compare
BWI76_RS15035 +0.8 1.0 metal ABC transporter permease compare
BWI76_RS25935 +0.8 2.6 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS09490 +0.8 2.5 DNA-binding response regulator compare
BWI76_RS02725 +0.8 1.1 HxlR family transcriptional regulator compare
BWI76_RS19805 +0.8 3.5 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS03015 +0.8 1.2 RNase E inhibitor protein compare
BWI76_RS24330 +0.8 1.5 TIGR00156 family protein compare
BWI76_RS15920 +0.8 1.5 hypothetical protein compare
BWI76_RS23140 +0.8 1.2 carboxysome shell protein compare
BWI76_RS00750 +0.8 1.8 ATP-dependent protease ATP-binding subunit HslU compare
BWI76_RS00995 +0.8 2.7 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS04565 +0.8 1.4 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS10570 +0.8 1.6 cysteine ABC transporter substrate-binding protein compare
BWI76_RS07165 +0.7 1.5 hypothetical protein compare
BWI76_RS06805 +0.7 1.1 primosomal replication protein N'' compare
BWI76_RS11125 +0.7 1.3 metal-dependent hydrolase compare
BWI76_RS19230 +0.7 1.4 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS13195 +0.7 1.8 glutamate dehydrogenase compare
BWI76_RS20230 +0.7 1.1 hypothetical protein compare
BWI76_RS09935 +0.7 3.2 paraquat-inducible membrane protein A compare
BWI76_RS27745 +0.7 2.5 PTS sugar transporter subunit IIB compare
BWI76_RS25290 +0.7 2.6 monofunctional biosynthetic peptidoglycan transglycosylase compare
BWI76_RS25245 +0.7 1.5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
BWI76_RS09155 +0.7 1.9 undecaprenyl-diphosphatase compare
BWI76_RS02870 +0.7 2.7 hypothetical protein compare
BWI76_RS20795 +0.7 1.0 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS24470 +0.7 3.3 hypothetical protein compare
BWI76_RS08840 +0.7 1.1 hypothetical protein compare
BWI76_RS18125 +0.7 2.4 murein DD-endopeptidase MepM compare
BWI76_RS17765 +0.7 1.4 hypothetical protein compare
BWI76_RS20720 +0.7 1.2 hypothetical protein compare
BWI76_RS07260 +0.7 2.1 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS12485 +0.7 2.8 TyrR family transcriptional regulator compare
BWI76_RS12860 +0.7 1.2 hypothetical protein compare
BWI76_RS08735 +0.7 2.7 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS15195 +0.7 1.9 DUF4186 domain-containing protein compare
BWI76_RS20565 +0.7 1.1 hypothetical protein compare
BWI76_RS17860 +0.7 1.5 YoaH family protein compare
BWI76_RS12780 +0.7 1.9 hypothetical protein compare
BWI76_RS04305 +0.7 0.6 molecular chaperone DnaJ compare
BWI76_RS07855 +0.7 1.1 PucR family transcriptional regulator compare
BWI76_RS14670 +0.7 1.7 hypothetical protein compare
BWI76_RS15795 +0.7 1.6 bacteriophage CII family protein compare
BWI76_RS22450 +0.7 2.1 selenoprotein W-related protein compare
BWI76_RS20725 +0.7 3.4 GNAT family acetyltransferase compare
BWI76_RS21075 +0.7 1.4 membrane protein compare
BWI76_RS05515 +0.6 2.4 NADH:ubiquinone reductase (Na(+)-transporting) subunit F compare
BWI76_RS25920 +0.6 1.2 peptidylprolyl isomerase compare
BWI76_RS25285 +0.6 0.8 HPr family phosphocarrier protein compare
BWI76_RS24785 +0.6 2.4 DUF805 domain-containing protein compare
BWI76_RS13545 +0.6 1.2 N-acetyltransferase compare
BWI76_RS08360 +0.6 1.7 LamB/YcsF family protein compare
BWI76_RS21495 +0.6 2.3 outer membrane lipoprotein compare
BWI76_RS24010 +0.6 1.5 hypothetical protein compare
BWI76_RS02920 +0.6 1.8 addiction module toxin RelE compare
BWI76_RS22935 +0.6 0.7 L-fucose mutarotase compare
BWI76_RS02860 +0.6 1.2 glycine dehydrogenase compare
BWI76_RS00640 +0.6 1.6 L-rhamnose mutarotase compare
BWI76_RS11525 +0.6 1.7 HNH endonuclease compare
BWI76_RS07475 +0.6 0.8 DNA-binding transcriptional regulator RamA compare
BWI76_RS20050 +0.6 1.1 hypothetical protein compare
BWI76_RS13135 +0.6 2.6 3-oxoadipyl-CoA thiolase compare
BWI76_RS23690 +0.6 1.1 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS16300 +0.6 1.9 bifunctional beta-cystathionase/maltose regulon regulatory protein compare
BWI76_RS07895 +0.6 2.9 sugar ABC transporter ATPase compare
BWI76_RS16055 +0.6 1.8 malonate decarboxylase subunit epsilon compare
BWI76_RS17165 +0.6 2.6 hypothetical protein compare
BWI76_RS24625 +0.6 3.2 hypothetical protein compare
BWI76_RS13360 +0.6 2.5 benzoate transporter compare
BWI76_RS01585 +0.6 1.7 transcriptional regulator compare
BWI76_RS19570 +0.6 2.0 3-hydroxybenzoate 6-hydroxylase compare
BWI76_RS13970 +0.6 1.2 ABC transporter compare
BWI76_RS06075 +0.6 1.1 taurine transporter subunit compare
BWI76_RS07745 +0.6 3.7 isochorismate synthase EntC compare
BWI76_RS25005 +0.6 2.1 biotin-independent malonate decarboxylase subunit beta compare
BWI76_RS23320 +0.6 1.0 hypothetical protein compare
BWI76_RS16240 +0.6 1.0 anti-adapter protein IraM compare
BWI76_RS04955 +0.6 0.9 hypoxanthine phosphoribosyltransferase compare
BWI76_RS25695 +0.6 2.4 ribosome alternative rescue factor ArfA compare
BWI76_RS13805 +0.6 2.1 inorganic diphosphatase compare
BWI76_RS10255 +0.6 2.4 dihydrodipicolinate synthase family protein compare
BWI76_RS15265 +0.6 2.2 hypothetical protein compare
BWI76_RS05510 +0.6 2.6 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS21445 +0.6 1.5 hypothetical protein compare
BWI76_RS27600 +0.6 2.3 tRNA-Sec compare
BWI76_RS13585 +0.6 1.3 4-oxalocrotonate tautomerase compare
BWI76_RS06540 +0.6 1.8 DNA-binding protein HU-beta compare
BWI76_RS05500 +0.6 2.6 NADH:ubiquinone reductase (Na(+)-transporting) subunit C compare
BWI76_RS19310 +0.6 1.5 ABC transporter permease compare
BWI76_RS16355 +0.6 1.1 electron transport complex subunit A compare
BWI76_RS16150 +0.6 1.5 IclR family transcriptional regulator compare
BWI76_RS16840 +0.6 2.4 ABC transporter compare
BWI76_RS20930 +0.6 0.9 arsenate reductase (glutaredoxin) compare
BWI76_RS11520 +0.6 0.7 hypothetical protein compare
BWI76_RS03610 +0.6 1.7 hypothetical protein compare
BWI76_RS21170 +0.6 2.1 tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ compare
BWI76_RS07705 +0.6 1.9 enterochelin esterase compare
BWI76_RS23535 +0.6 1.0 hypothetical protein compare
BWI76_RS14415 +0.6 1.0 transcriptional regulator, TetR family protein compare
BWI76_RS25070 +0.6 0.9 hypothetical protein compare
BWI76_RS09860 +0.5 1.7 hypothetical protein compare
BWI76_RS15895 +0.5 3.6 starvation-sensing protein RspA compare
BWI76_RS13315 +0.5 1.4 50S ribosomal protein L7/L12-serine acetyltransferase compare
BWI76_RS13150 +0.5 1.5 carnitine operon protein CaiE compare
BWI76_RS24745 +0.5 1.7 membrane protein compare
BWI76_RS18070 +0.5 2.0 DNA polymerase III subunit epsilon compare
BWI76_RS09030 +0.5 2.5 transpeptidase compare
BWI76_RS03025 +0.5 0.9 N-acetyltransferase compare
BWI76_RS27650 +0.5 2.0 EamA family transporter compare
BWI76_RS08750 +0.5 0.9 kinase inhibitor compare
BWI76_RS07750 +0.5 3.3 2,3-dihydroxybenzoate-AMP ligase compare
BWI76_RS03825 +0.5 1.8 4-hydroxyphenylacetate 3-monooxygenase compare
BWI76_RS22975 +0.5 1.1 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA compare
BWI76_RS05655 +0.5 1.9 hypothetical protein compare
BWI76_RS16035 +0.5 2.0 biotin-independent malonate decarboxylase subunit beta compare
BWI76_RS16270 +0.5 2.6 fumarate hydratase, class II compare
BWI76_RS05465 +0.5 0.8 amidohydrolase compare
BWI76_RS15185 +0.5 1.9 N-acetyltransferase compare
BWI76_RS17645 +0.5 1.8 hypothetical protein compare
BWI76_RS17190 +0.5 1.3 TonB system transport protein TonB compare
BWI76_RS17650 +0.5 2.2 putative fatty acid desaturase compare
BWI76_RS14930 +0.5 1.6 hypothetical protein compare
BWI76_RS05695 +0.5 2.1 anaerobic C4-dicarboxylate transporter compare
BWI76_RS11950 +0.5 1.7 phosphatidylglycerophosphatase B compare
BWI76_RS22815 +0.5 3.3 hybrid sensor histidine kinase/response regulator compare
BWI76_RS24180 +0.5 1.0 hypothetical protein compare
BWI76_RS03870 +0.5 1.5 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase compare
BWI76_RS20925 +0.5 1.9 peptidase M48 compare
BWI76_RS14680 +0.5 1.5 SefF compare
BWI76_RS18295 +0.5 1.6 tyrosine transporter TyrP compare
BWI76_RS19300 +0.5 2.0 ABC transporter ATP-binding protein compare
BWI76_RS14980 +0.5 1.1 hypothetical protein compare
BWI76_RS26285 +0.5 1.9 glycerophosphodiester phosphodiesterase compare
BWI76_RS11435 +0.5 1.1 hypothetical protein compare
BWI76_RS17350 +0.5 1.0 DNA-binding response regulator compare
BWI76_RS09865 +0.5 2.2 MBL fold hydrolase compare
BWI76_RS09610 +0.5 2.2 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS08800 +0.5 2.0 phosphoethanolamine transferase EptA compare
BWI76_RS21710 +0.5 2.1 nitroreductase compare
BWI76_RS13515 +0.5 1.7 amino acid permease compare
BWI76_RS07740 +0.5 0.9 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS17315 +0.5 2.4 EamA family transporter compare
BWI76_RS21660 +0.5 1.0 antirestriction protein compare
BWI76_RS07795 +0.5 2.5 oxidoreductase compare
BWI76_RS05550 +0.5 2.7 fermentation/respiration switch protein compare
BWI76_RS22725 +0.5 2.4 type I-E CRISPR-associated protein Cas6/Cse3/CasE compare
BWI76_RS06880 +0.5 1.6 biopolymer transport protein ExbD/TolR compare
BWI76_RS06130 +0.5 1.4 extensin family protein compare
BWI76_RS09625 +0.5 1.0 hypothetical protein compare
BWI76_RS06400 +0.5 0.5 oxidative-stress-resistance chaperone compare
BWI76_RS06405 +0.5 1.3 2-dehydropantoate 2-reductase compare
BWI76_RS10755 +0.5 0.9 pyrimidine utilization flavin reductase protein F compare
BWI76_RS06335 +0.5 1.2 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS22960 +0.5 1.6 YgdI/YgdR family lipoprotein compare
BWI76_RS08820 +0.5 1.2 molybdenum cofactor biosynthesis protein compare
BWI76_RS20335 +0.5 2.4 zinc transporter compare
BWI76_RS07255 +0.5 0.7 hypothetical protein compare
BWI76_RS09520 +0.5 1.1 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS11055 +0.5 1.4 hydrolase compare
BWI76_RS11895 +0.5 1.7 AraC family transcriptional regulator compare
BWI76_RS22135 +0.5 1.8 transport-associated protein compare
BWI76_RS22315 +0.5 2.0 formate hydrogenlyase complex iron-sulfur subunit compare
BWI76_RS16170 +0.5 1.2 amidohydrolase compare
BWI76_RS15975 +0.5 0.7 hypothetical protein compare
BWI76_RS15785 +0.5 1.9 replication protein compare
BWI76_RS14410 +0.5 1.5 hypothetical protein compare
BWI76_RS23060 +0.5 2.0 cobalt-precorrin-4 C(11)-methyltransferase compare
BWI76_RS07645 +0.5 0.8 short-chain dehydrogenase/reductase compare
BWI76_RS14620 +0.5 1.4 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium L-Lactate across organisms