Experiment set5IT045 for Pseudomonas fluorescens GW456-L13

Compare to:

LB

200 most important genes:

  gene name fitness t score description  
PfGW456L13_5017 -3.1 -3.6 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_427 -3.0 -2.0 Two-component system response regulator OmpR compare
PfGW456L13_4026 -3.0 -2.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_787 -2.5 -7.1 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_426 -2.4 -6.7 Osmolarity sensory histidine kinase EnvZ compare
PfGW456L13_420 -2.1 -2.8 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_1655 -1.9 -2.8 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_1363 -1.9 -3.3 Rare lipoprotein A precursor compare
PfGW456L13_157 -1.9 -3.7 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
PfGW456L13_2010 -1.9 -3.5 outer membrane protein H1 compare
PfGW456L13_5112 -1.9 -1.7 tmRNA-binding protein SmpB compare
PfGW456L13_2084 -1.8 -1.7 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_4233 -1.7 -2.8 Transcriptional regulator, MarR family compare
PfGW456L13_1009 -1.7 -1.1 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_2594 -1.6 -2.6 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
PfGW456L13_1774 -1.6 -3.8 Iron-regulated protein A precursor compare
PfGW456L13_2941 -1.6 -2.8 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_4125 -1.6 -1.5 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_59 -1.5 -4.8 Sensor histidine kinase/response regulator compare
PfGW456L13_2981 -1.5 -1.5 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_2011 -1.5 -1.0 Transcriptional regulatory protein PhoP compare
PfGW456L13_1838 -1.4 -2.2 Sensory box histidine kinase compare
PfGW456L13_2012 -1.4 -7.8 Sensor protein PhoQ (EC 2.7.13.3) compare
PfGW456L13_594 -1.4 -3.3 DNA polymerase I (EC 2.7.7.7) compare
PfGW456L13_2792 -1.4 -2.6 Phage tail protein compare
PfGW456L13_1773 -1.4 -4.3 putative exported protein compare
PfGW456L13_5086 -1.3 -0.9 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_3705 -1.3 -3.0 hypothetical protein compare
PfGW456L13_4513 -1.3 -2.1 HtrA protease/chaperone protein compare
PfGW456L13_1198 -1.3 -3.4 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
PfGW456L13_2164 -1.2 -3.6 Thioredoxin compare
PfGW456L13_1524 -1.2 -3.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_4346 -1.2 -2.2 Hpt domain protein compare
PfGW456L13_482 -1.2 -3.8 FIG028593: membrane protein compare
PfGW456L13_1479 -1.2 -0.7 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
PfGW456L13_1625 -1.2 -2.2 FIG00958649: hypothetical protein compare
PfGW456L13_858 -1.2 -2.8 Uroporphyrinogen-III synthase (EC 4.2.1.75) compare
PfGW456L13_1983 -1.2 -1.4 hypothetical protein compare
PfGW456L13_276 -1.2 -0.7 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_5241 -1.1 -2.3 tRNA-Thr-CGT compare
PfGW456L13_591 -1.1 -1.4 Cytochrome c4 compare
PfGW456L13_4008 -1.1 -2.6 hypothetical protein compare
PfGW456L13_5048 -1.1 -1.6 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_4781 -1.1 -1.3 Nudix hydrolase family protein PA3470 compare
PfGW456L13_2015 -1.1 -2.4 hypothetical protein compare
PfGW456L13_756 -1.1 -2.4 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_1973 -1.1 -2.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_705 -1.1 -1.2 FIG00953800: hypothetical protein compare
PfGW456L13_1447 -1.0 -1.7 Transcriptional regulator, GntR family compare
PfGW456L13_202 -1.0 -2.9 Probable transcription regulator Mig-14 compare
PfGW456L13_3894 -1.0 -1.1 Integration host factor alpha subunit compare
PfGW456L13_2185 -1.0 -2.1 putative colanic acid biosynthesis glycosyl transferase compare
PfGW456L13_3979 -1.0 -3.7 hypothetical protein compare
PfGW456L13_722 -1.0 -4.6 putative membrane protein compare
PfGW456L13_1997 -1.0 -3.4 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_2955 -0.9 -2.5 RND efflux system, membrane fusion protein CmeA compare
PfGW456L13_172 -0.9 -4.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_4067 -0.9 -2.7 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
PfGW456L13_4041 -0.9 -1.5 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_943 -0.9 -4.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_4088 -0.9 -1.4 Transcriptional regulator, GntR family compare
PfGW456L13_2874 -0.9 -3.8 D-beta-hydroxybutyrate permease compare
PfGW456L13_3845 -0.9 -1.2 Predicted secretion system X transmembrane protein 1 compare
PfGW456L13_2436 -0.9 -2.9 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1628 -0.9 -3.8 ATPase, AFG1 family compare
PfGW456L13_3893 -0.9 -2.9 Transcriptional regulator, MerR family compare
PfGW456L13_5117 -0.9 -3.1 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
PfGW456L13_2385 -0.9 -1.2 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
PfGW456L13_2707 -0.9 -1.1 FIG00953208: hypothetical protein compare
PfGW456L13_2710 -0.9 -4.7 hypothetical protein compare
PfGW456L13_403 -0.9 -2.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
PfGW456L13_2277 -0.9 -1.6 DNA-binding response regulator, LuxR family compare
PfGW456L13_352 -0.9 -1.8 FIG136845: Rhodanese-related sulfurtransferase compare
PfGW456L13_2107 -0.9 -2.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
PfGW456L13_4014 -0.8 -1.2 Chromosome segregation ATPases compare
PfGW456L13_2038 -0.8 -2.1 hypothetical protein compare
PfGW456L13_3052 -0.8 -1.5 Response regulator compare
PfGW456L13_565 -0.8 -3.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_1887 -0.8 -2.5 Methylglyoxal synthase (EC 4.2.3.3) compare
PfGW456L13_3986 -0.8 -2.8 Shufflon-specific DNA recombinase compare
PfGW456L13_2603 -0.8 -1.0 Transcriptional regulator, MarR family compare
PfGW456L13_5003 -0.8 -1.1 YrbA protein compare
PfGW456L13_4769 -0.8 -2.1 hypothetical protein compare
PfGW456L13_751 -0.8 -1.8 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
PfGW456L13_4238 -0.8 -2.6 Cobyric acid synthase (EC 6.3.5.10) compare
PfGW456L13_1041 -0.8 -1.1 Putative translation initiation inhibitor, yjgF family compare
PfGW456L13_952 -0.8 -2.6 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_2538 -0.8 -1.2 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
PfGW456L13_990 -0.8 -1.7 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_3499 -0.8 -1.9 Short-chain dehydrogenase/reductase SDR compare
PfGW456L13_2833 -0.8 -2.2 hypothetical protein compare
PfGW456L13_4641 -0.8 -1.7 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
PfGW456L13_4413 -0.8 -4.6 Potassium uptake protein TrkH compare
PfGW456L13_1763 -0.8 -2.2 FxsA protein compare
PfGW456L13_5105 -0.8 -1.8 hypothetical protein compare
PfGW456L13_213 -0.8 -5.7 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
PfGW456L13_2424 -0.8 -1.4 Phenylacetate-CoA oxygenase, PaaJ subunit compare
PfGW456L13_2842 -0.8 -2.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_4038 -0.7 -1.3 DNA topoisomerase I (EC 5.99.1.2) compare
PfGW456L13_3289 -0.7 -1.8 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
PfGW456L13_922 -0.7 -2.0 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_3444 -0.7 -1.8 Transcriptional regulator, TetR family compare
PfGW456L13_1824 -0.7 -1.1 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_2857 -0.7 -0.9 ChlD component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_597 -0.7 -4.9 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
PfGW456L13_1972 -0.7 -0.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_1850 -0.7 -2.3 FIG000859: hypothetical protein YebC compare
PfGW456L13_328 -0.7 -1.5 Conserved hypothetical protein (perhaps related to histidine degradation) compare
PfGW456L13_152 -0.7 -0.5 HflK protein compare
PfGW456L13_942 -0.7 -2.3 ATPases of the AAA+ class compare
PfGW456L13_1637 -0.7 -2.7 Stringent starvation protein A compare
PfGW456L13_275 -0.7 -0.6 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_4934 -0.7 -3.1 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
PfGW456L13_358 -0.7 -1.1 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_5060 -0.7 -1.6 Peptide chain release factor 3 compare
PfGW456L13_849 -0.7 -1.8 Regulator of nucleoside diphosphate kinase compare
PfGW456L13_3321 -0.7 -2.3 Transcriptional regulator of the arabinose operon in Shewanella, GntR family compare
PfGW456L13_3148 -0.7 -2.2 L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1) compare
PfGW456L13_4865 -0.7 -2.2 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) compare
PfGW456L13_4253 -0.7 -1.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_4134 -0.7 -1.1 hypothetical protein compare
PfGW456L13_4165 -0.7 -1.0 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_2942 -0.7 -1.4 hypothetical protein compare
PfGW456L13_3367 -0.7 -2.5 Probable carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) compare
PfGW456L13_1981 -0.7 -3.3 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_2279 -0.7 -1.5 FIG00953472: hypothetical protein compare
PfGW456L13_4305 -0.7 -2.9 Transcriptional regulator, LysR family compare
PfGW456L13_4961 -0.7 -2.8 Fumarylacetoacetase (EC 3.7.1.2) compare
PfGW456L13_4035 -0.7 -0.9 Cell division inhibitor-related protein compare
PfGW456L13_4642 -0.6 -1.3 Cold shock protein CspA compare
PfGW456L13_3859 -0.6 -1.0 Nicotinamidase family protein YcaC compare
PfGW456L13_2321 -0.6 -1.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_2396 -0.6 -0.6 Mg(2+) transport ATPase, P-type (EC 3.6.3.2) compare
PfGW456L13_4487 -0.6 -1.3 FIG00954793: hypothetical protein compare
PfGW456L13_2191 -0.6 -3.8 nucleotide sugar epimerase/dehydratase WbpM compare
PfGW456L13_1900 -0.6 -3.9 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_4358 -0.6 -3.2 FIG00953167: hypothetical protein compare
PfGW456L13_1574 -0.6 -1.2 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_4071 -0.6 -1.4 Fumarate and nitrate reduction regulatory protein compare
PfGW456L13_3179 -0.6 -0.9 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2451 -0.6 -1.8 Two-component system response regulator QseB compare
PfGW456L13_355 -0.6 -1.4 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_4424 -0.6 -1.4 FIG00953416: hypothetical protein compare
PfGW456L13_2589 -0.6 -2.3 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
PfGW456L13_652 -0.6 -2.6 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
PfGW456L13_3134 -0.6 -2.1 Short-chain dehydrogenase/reductase SDR compare
PfGW456L13_329 -0.6 -1.3 Histidine utilization repressor compare
PfGW456L13_4495 -0.6 -1.7 Protein YcgL compare
PfGW456L13_4507 -0.6 -0.9 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_3012 -0.6 -1.2 Fap amyloid fibril minor component compare
PfGW456L13_950 -0.6 -2.9 Predicted integral membrane protein compare
PfGW456L13_2033 -0.6 -2.9 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
PfGW456L13_2309 -0.6 -2.8 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
PfGW456L13_2190 -0.6 -1.5 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
PfGW456L13_2300 -0.6 -3.6 Sensor histidine kinase compare
PfGW456L13_4506 -0.6 -2.6 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
PfGW456L13_4582 -0.6 -1.5 RND efflux system, outer membrane lipoprotein CmeC compare
PfGW456L13_4036 -0.6 -1.2 FIG00954079: hypothetical protein compare
PfGW456L13_2257 -0.6 -1.9 putative ATP/GTP-binding protein compare
PfGW456L13_1789 -0.6 -1.1 FIG00954094: hypothetical protein compare
PfGW456L13_864 -0.6 -2.2 hypothetical protein compare
PfGW456L13_1068 -0.6 -2.9 Lipoprotein, putative compare
PfGW456L13_3475 -0.6 -1.4 Stress responsive alpha-beta barrel domain protein Dabb compare
PfGW456L13_1370 -0.6 -1.5 FIG00957593: hypothetical protein compare
PfGW456L13_3406 -0.6 -1.4 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) compare
PfGW456L13_4243 -0.6 -1.5 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) compare
PfGW456L13_5005 -0.6 -1.0 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_4737 -0.6 -1.0 FIG00953063: hypothetical protein compare
PfGW456L13_2804 -0.6 -1.6 Cytochrome c5 compare
PfGW456L13_4512 -0.6 -1.6 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_1863 -0.6 -2.2 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_1693 -0.6 -3.3 YheO-like PAS domain compare
PfGW456L13_4603 -0.6 -2.8 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) compare
PfGW456L13_72 -0.6 -1.2 hypothetical protein compare
PfGW456L13_3641 -0.6 -1.0 hypothetical protein compare
PfGW456L13_1982 -0.6 -0.9 Carbon storage regulator compare
PfGW456L13_600 -0.6 -2.6 Zinc ABC transporter, inner membrane permease protein ZnuB compare
PfGW456L13_4107 -0.6 -2.0 CmpX compare
PfGW456L13_4876 -0.6 -2.6 tRNA:Cm32/Um32 methyltransferase compare
PfGW456L13_1300 -0.6 -1.6 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
PfGW456L13_86 -0.6 -2.5 Urease accessory protein UreD compare
PfGW456L13_1639 -0.6 -2.0 21 kDa hemolysin precursor compare
PfGW456L13_1643 -0.6 -2.6 rRNA small subunit methyltransferase I compare
PfGW456L13_1233 -0.6 -1.5 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_2650 -0.6 -3.1 Thioredoxin reductase (EC 1.8.1.9) compare
PfGW456L13_4836 -0.6 -2.9 Transglycosylase, Slt family compare
PfGW456L13_4012 -0.6 -0.6 VacJ-like lipoprotein precursor compare
PfGW456L13_3873 -0.5 -1.4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) compare
PfGW456L13_18 -0.5 -3.1 Transcriptional regulator, LysR family compare
PfGW456L13_3773 -0.5 -1.4 Copper metallochaperone, bacterial analog of Cox17 protein compare
PfGW456L13_4911 -0.5 -1.5 Transcriptional regulator, LysR family compare
PfGW456L13_4671 -0.5 -1.8 Transcriptional regulator, Cro/CI family compare
PfGW456L13_2551 -0.5 -1.1 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_4888 -0.5 -2.2 NAD-dependent formate dehydrogenase delta subunit compare
PfGW456L13_3351 -0.5 -0.9 Putative Isoquinoline 1-oxidoreductase subunit, Mll3835 protein compare
PfGW456L13_773 -0.5 -1.9 Hydrogen peroxide-inducible genes activator compare
PfGW456L13_844 -0.5 -1.2 Diaminopimelate epimerase (EC 5.1.1.7) compare
PfGW456L13_2327 -0.5 -1.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_715 -0.5 -3.0 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
PfGW456L13_2048 -0.5 -2.3 Phosphohistidine phosphatase SixA compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens GW456-L13 in lb experiments

For lb Kanamycin sulfate across organisms