Experiment set5IT044 for Klebsiella michiganensis M5al

Compare to:

Trisodium citrate dihydrate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS04305 +1.5 1.6 molecular chaperone DnaJ compare
BWI76_RS13280 +1.5 9.3 LysR family transcriptional regulator compare
BWI76_RS24575 +1.4 1.9 hypothetical protein compare
BWI76_RS03045 +1.4 2.4 hypothetical protein compare
BWI76_RS14770 +1.4 2.7 PTS IIA 2 domain protein compare
BWI76_RS20795 +1.3 2.2 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS19770 +1.2 2.9 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS01995 +1.2 1.8 AraC family transcriptional regulator compare
BWI76_RS11255 +1.2 2.0 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS13420 +1.1 2.5 ABC transporter permease compare
BWI76_RS13250 +1.1 1.7 cytochrome b561 compare
BWI76_RS16355 +1.1 1.2 electron transport complex subunit A compare
BWI76_RS18780 +1.1 3.3 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS24080 +1.0 2.1 DUF179 domain-containing protein compare
BWI76_RS15015 +1.0 1.7 DUF2132 domain-containing protein compare
BWI76_RS25285 +1.0 1.3 HPr family phosphocarrier protein compare
BWI76_RS08645 +1.0 2.0 molybdate ABC transporter substrate-binding protein compare
BWI76_RS21245 +0.9 1.8 nitrogen regulatory protein P-II compare
BWI76_RS12485 +0.9 2.8 TyrR family transcriptional regulator compare
BWI76_RS07970 +0.9 2.6 hypothetical protein compare
BWI76_RS16935 +0.9 1.3 shikimate dehydrogenase compare
BWI76_RS10575 +0.9 2.0 polar amino acid ABC transporter permease compare
BWI76_RS11525 +0.9 1.8 HNH endonuclease compare
BWI76_RS10435 +0.8 2.9 suppressor for copper-sensitivity C compare
BWI76_RS27225 +0.8 2.0 rhodanese-like domain-containing protein compare
BWI76_RS16485 +0.8 1.8 ribonuclease T compare
BWI76_RS07475 +0.8 1.1 DNA-binding transcriptional regulator RamA compare
BWI76_RS05465 +0.8 1.4 amidohydrolase compare
BWI76_RS05950 +0.8 1.8 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS17470 +0.8 2.0 MerR family transcriptional regulator compare
BWI76_RS17045 +0.8 1.2 hypothetical protein compare
BWI76_RS15950 +0.8 2.0 dethiobiotin synthase compare
BWI76_RS17915 +0.8 3.6 membrane protein compare
BWI76_RS14670 +0.8 1.9 hypothetical protein compare
BWI76_RS00790 +0.7 3.3 bifunctional aspartokinase II/homoserine dehydrogenase II compare
BWI76_RS00715 +0.7 2.4 two-component sensor histidine kinase compare
BWI76_RS11170 +0.7 1.3 hypothetical protein compare
BWI76_RS06540 +0.7 1.8 DNA-binding protein HU-beta compare
BWI76_RS20940 +0.7 1.6 uracil/xanthine transporter compare
BWI76_RS15135 +0.7 2.8 hypothetical protein compare
BWI76_RS17350 +0.7 2.0 DNA-binding response regulator compare
BWI76_RS17200 +0.7 1.4 hypothetical protein compare
BWI76_RS19935 +0.7 1.4 hypothetical protein compare
BWI76_RS12780 +0.7 1.0 hypothetical protein compare
BWI76_RS03025 +0.7 1.5 N-acetyltransferase compare
BWI76_RS16895 +0.7 1.6 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS17570 +0.7 2.0 iron-sulfur-binding protein compare
BWI76_RS26205 +0.7 2.2 glucose-1-phosphate adenylyltransferase compare
BWI76_RS16795 +0.7 1.8 amino acid ABC transporter ATPase compare
BWI76_RS18650 +0.7 2.7 fimbrial protein compare
BWI76_RS08280 +0.7 2.5 acyl-CoA esterase compare
BWI76_RS01560 +0.7 3.8 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS11285 +0.7 1.4 transcriptional regulator compare
BWI76_RS11435 +0.7 0.8 hypothetical protein compare
BWI76_RS20360 +0.7 0.9 cell division protein DedD compare
BWI76_RS05555 +0.7 1.6 Crl family RNA polymerase assembly factor compare
BWI76_RS07785 +0.7 2.0 transcriptional regulator compare
BWI76_RS17765 +0.7 1.2 hypothetical protein compare
BWI76_RS00590 +0.7 1.8 hypothetical protein compare
BWI76_RS14865 +0.7 3.4 ribose ABC transporter permease compare
BWI76_RS16000 +0.6 1.1 multidrug transporter subunit MdtI compare
BWI76_RS10430 +0.6 1.2 thiol:disulfide interchange protein DsbG compare
BWI76_RS06520 +0.6 2.9 trigger factor compare
BWI76_RS00750 +0.6 1.7 ATP-dependent protease ATP-binding subunit HslU compare
BWI76_RS13610 +0.6 3.3 sugar transporter compare
BWI76_RS11440 +0.6 0.9 hypothetical protein compare
BWI76_RS02050 +0.6 1.7 CidA/LrgA family protein compare
BWI76_RS08600 +0.6 2.6 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS12170 +0.6 1.5 hypothetical protein compare
BWI76_RS05965 +0.6 1.2 hypothetical protein compare
BWI76_RS12040 +0.6 0.9 hypothetical protein compare
BWI76_RS09830 +0.6 1.5 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
BWI76_RS25235 +0.6 2.5 calcium/sodium antiporter compare
BWI76_RS24720 +0.6 1.0 hypothetical protein compare
BWI76_RS07345 +0.6 2.5 family 3 extracellular solute-binding protein compare
BWI76_RS17315 +0.6 3.0 EamA family transporter compare
BWI76_RS23125 +0.6 1.0 propanediol dehydratase small subunit compare
BWI76_RS16950 +0.6 0.9 TetR family transcriptional regulator compare
BWI76_RS27005 +0.6 2.7 hypothetical protein compare
BWI76_RS21170 +0.6 2.7 tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ compare
BWI76_RS23340 +0.6 1.6 transcriptional regulator compare
BWI76_RS06130 +0.6 2.0 extensin family protein compare
BWI76_RS15095 +0.6 1.7 isochorismatase compare
BWI76_RS08275 +0.6 1.0 LexA regulated protein compare
BWI76_RS06405 +0.6 1.2 2-dehydropantoate 2-reductase compare
BWI76_RS10580 +0.6 2.4 amino acid ABC transporter permease compare
BWI76_RS21565 +0.6 0.9 outer membrane protein assembly factor BamE compare
BWI76_RS14375 +0.6 2.0 hypothetical protein compare
BWI76_RS19865 +0.6 1.3 ecotin compare
BWI76_RS24470 +0.6 2.4 hypothetical protein compare
BWI76_RS13335 +0.6 2.6 peptidase T compare
BWI76_RS19195 +0.6 1.3 nickel ABC transporter permease compare
BWI76_RS20730 +0.6 1.3 hypothetical protein compare
BWI76_RS22850 +0.6 1.7 tRNA pseudouridine synthase TruC compare
BWI76_RS00655 +0.6 3.1 inner-membrane translocator compare
BWI76_RS23755 +0.6 1.8 transcriptional regulator compare
BWI76_RS15960 +0.6 2.9 LysR family transcriptional regulator compare
BWI76_RS21285 +0.6 1.2 HAD family hydrolase compare
BWI76_RS17465 +0.6 3.0 C4-dicarboxylic acid transporter DauA compare
BWI76_RS21345 +0.6 1.1 sigma-E factor regulatory protein RseB compare
BWI76_RS08750 +0.6 1.0 kinase inhibitor compare
BWI76_RS17955 +0.5 2.3 hypothetical protein compare
BWI76_RS15150 +0.5 2.3 outer membrane efflux protein compare
BWI76_RS14650 +0.5 1.7 helix-turn-helix transcriptional regulator compare
BWI76_RS26505 +0.5 2.1 nickel ABC transporter permease subunit NikB compare
BWI76_RS11890 +0.5 1.2 glycosyl hydrolase compare
BWI76_RS20900 +0.5 0.9 outer membrane protein assembly factor BamC compare
BWI76_RS23030 +0.5 1.2 cobalamin biosynthesis protein CbiM compare
BWI76_RS17945 +0.5 1.2 hypothetical protein compare
BWI76_RS20430 +0.5 1.8 penicillin-insensitive murein endopeptidase compare
BWI76_RS13790 +0.5 2.1 peptide ABC transporter permease compare
BWI76_RS12910 +0.5 1.3 3,4-dihydroxyphenylacetate 2,3-dioxygenase compare
BWI76_RS18125 +0.5 2.3 murein DD-endopeptidase MepM compare
BWI76_RS04970 +0.5 1.6 ABC transporter permease compare
BWI76_RS13415 +0.5 1.4 spermidine/putrescine ABC transporter permease compare
BWI76_RS05710 +0.5 2.2 TetR family transcriptional regulator compare
BWI76_RS26285 +0.5 1.7 glycerophosphodiester phosphodiesterase compare
BWI76_RS13325 +0.5 1.4 dicarboxylate transporter/tellurite-resistance protein TehA compare
BWI76_RS13710 +0.5 1.6 benzoate 1,2-dioxygenase small subunit compare
BWI76_RS27915 +0.5 0.6 YceK/YidQ family lipoprotein compare
BWI76_RS13395 +0.5 2.3 cytochrome D ubiquinol oxidase subunit I compare
BWI76_RS08360 +0.5 2.3 LamB/YcsF family protein compare
BWI76_RS05810 +0.5 0.8 hypothetical protein compare
BWI76_RS01010 +0.5 1.7 uridine phosphorylase compare
BWI76_RS16120 +0.5 1.5 4-carboxymuconolactone decarboxylase compare
BWI76_RS08735 +0.5 1.8 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS21535 +0.5 2.3 inner membrane protein YpjD compare
BWI76_RS16525 +0.5 2.1 cyclopropane-fatty-acyl-phospholipid synthase compare
BWI76_RS21905 +0.5 2.4 class II aldolase compare
BWI76_RS02810 +0.5 2.2 sugar ABC transporter permease YjfF compare
BWI76_RS11700 +0.5 0.7 hypothetical protein compare
BWI76_RS06880 +0.5 1.8 biopolymer transport protein ExbD/TolR compare
BWI76_RS07165 +0.5 0.8 hypothetical protein compare
BWI76_RS08765 +0.5 1.7 8-amino-7-oxononanoate synthase compare
BWI76_RS14540 +0.5 1.2 yersiniabactin biosynthetic protein YbtU compare
BWI76_RS22090 +0.5 1.3 transcriptional regulator compare
BWI76_RS05410 +0.5 1.9 2,5-didehydrogluconate reductase B compare
BWI76_RS18810 +0.5 0.9 nitrogenase iron protein compare
BWI76_RS04655 +0.5 1.5 shikimate dehydrogenase compare
BWI76_RS00285 +0.5 1.5 D-ribose ABC transporter substrate-binding protein compare
BWI76_RS23515 +0.5 1.6 antibiotic biosynthesis monooxygenase compare
BWI76_RS25935 +0.5 1.8 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS13150 +0.5 1.4 carnitine operon protein CaiE compare
BWI76_RS13195 +0.5 1.1 glutamate dehydrogenase compare
BWI76_RS17185 +0.5 2.0 fructosamine kinase family protein compare
BWI76_RS08840 +0.5 2.2 hypothetical protein compare
BWI76_RS02520 +0.5 3.6 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS02860 +0.5 1.7 glycine dehydrogenase compare
BWI76_RS23900 +0.5 2.5 hypothetical protein compare
BWI76_RS16015 +0.5 1.6 pheromone autoinducer 2 transporter compare
BWI76_RS00830 +0.5 1.7 metal-binding protein ZinT compare
BWI76_RS05045 +0.5 1.1 general secretion pathway protein GspM compare
BWI76_RS16785 +0.5 1.7 peptidase M20 compare
BWI76_RS13330 +0.5 0.9 tellurite resistance methyltransferase TehB compare
BWI76_RS24225 +0.5 1.2 hypothetical protein compare
BWI76_RS15035 +0.5 0.6 metal ABC transporter permease compare
BWI76_RS26095 +0.5 0.8 shikimate kinase compare
BWI76_RS13775 +0.5 1.1 putative FMN-dependent luciferase-like monooxygenase compare
BWI76_RS19535 +0.5 1.8 putative integral membrane protein compare
BWI76_RS13805 +0.5 1.6 inorganic diphosphatase compare
BWI76_RS23735 +0.5 1.4 sugar diacid utilization regulator compare
BWI76_RS20560 +0.5 1.4 hypothetical protein compare
BWI76_RS15985 +0.5 2.4 LysR family transcriptional regulator compare
BWI76_RS24885 +0.5 0.7 PTS galactitol transporter subunit IIB compare
BWI76_RS18755 +0.5 0.7 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS09170 +0.5 2.2 MFS transporter compare
BWI76_RS20845 +0.5 2.0 GDP-mannose pyrophosphatase NudK compare
BWI76_RS08640 +0.5 1.1 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS04175 +0.5 1.2 energy-dependent translational throttle protein EttA compare
BWI76_RS20140 +0.5 2.9 NADH-quinone oxidoreductase subunit L compare
BWI76_RS16475 +0.5 2.2 alkene reductase compare
BWI76_RS11430 +0.5 0.6 lipoprotein compare
BWI76_RS23185 +0.5 1.7 propanediol utilization: polyhedral bodies pduT compare
BWI76_RS06120 +0.5 1.3 membrane protein compare
BWI76_RS20155 +0.5 0.9 NADH-quinone oxidoreductase subunit I compare
BWI76_RS25295 +0.5 2.6 glutamine amidotransferase compare
BWI76_RS24105 +0.5 1.6 resistance protein compare
BWI76_RS01700 +0.5 2.0 dipeptidase E compare
BWI76_RS20130 +0.5 1.6 NADH-quinone oxidoreductase subunit N compare
BWI76_RS18060 +0.5 1.0 hypothetical protein compare
BWI76_RS14620 +0.5 1.4 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase compare
BWI76_RS20520 +0.5 2.7 indolepyruvate decarboxylase compare
BWI76_RS13135 +0.5 1.7 3-oxoadipyl-CoA thiolase compare
BWI76_RS17805 +0.5 0.7 membrane protein compare
BWI76_RS04560 +0.5 1.0 holo-ACP synthase CitX compare
BWI76_RS24810 +0.4 1.1 hypothetical protein compare
BWI76_RS20945 +0.4 2.1 uracil phosphoribosyltransferase compare
BWI76_RS03015 +0.4 1.6 RNase E inhibitor protein compare
BWI76_RS04060 +0.4 0.6 hypothetical protein compare
BWI76_RS23530 +0.4 1.1 MarR family transcriptional regulator compare
BWI76_RS10650 +0.4 1.9 PTS fructose-like transporter subunit EIIB compare
BWI76_RS06745 +0.4 1.5 N-acetyltransferase GCN5 compare
BWI76_RS13635 +0.4 2.8 extracellular solute-binding protein compare
BWI76_RS18915 +0.4 1.3 NAD(P)-dependent oxidoreductase compare
BWI76_RS24925 +0.4 1.0 DnaA initiator-associating protein DiaA compare
BWI76_RS14625 +0.4 0.8 protein TolA compare
BWI76_RS13515 +0.4 1.6 amino acid permease compare
BWI76_RS08650 +0.4 1.3 molybdate ABC transporter permease compare
BWI76_RS22235 +0.4 1.3 transcriptional regulator GutM compare
BWI76_RS22070 +0.4 1.9 proline/betaine ABC transporter permease ProW compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source Trisodium citrate dihydrate in Klebsiella michiganensis M5al

For carbon source Trisodium citrate dihydrate across organisms