Experiment set5IT032 for Methanococcus maripaludis S2

Compare to:

Formate with cyanide 50 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS00450 +0.8 2.3 4Fe-4S binding protein compare
MMP_RS02790 +0.8 2.1 class III signal peptide-containing protein compare
MMP_RS02470 +0.8 1.4 helix-turn-helix transcriptional regulator compare
MMP_RS03320 +0.7 3.2 metal-dependent transcriptional regulator compare
MMP_RS07820 +0.6 3.8 UPF0104 family protein compare
MMP_RS07415 +0.6 4.7 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS01775 +0.5 1.8 TIGR00297 family protein compare
MMP_RS03390 +0.5 3.7 malate dehydrogenase compare
MMP_RS08315 +0.5 2.6 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS09025 +0.5 1.1 hypothetical protein compare
MMP_RS02310 +0.5 1.5 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS06600 +0.4 0.8 class III signal peptide-containing protein compare
MMP_RS06540 +0.4 2.4 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS06905 +0.4 1.2 hypothetical protein compare
MMP_RS06535 +0.4 2.7 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01700 +0.4 0.8 dihydroxy-acid dehydratase compare
MMP_RS08155 +0.4 2.5 hypothetical protein compare
MMP_RS07125 +0.4 2.3 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00635 +0.4 2.2 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS01095 +0.4 2.7 iron ABC transporter permease compare
MMP_RS01385 +0.4 0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS08660 +0.4 2.4 DHH family phosphoesterase compare
MMP_RS06460 +0.4 2.0 pyrimidine dimer DNA glycosylase/endonuclease V compare
MMP_RS05720 +0.4 2.4 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS02595 +0.4 1.0 putative zinc-binding protein compare
MMP_RS07120 +0.3 2.9 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06530 +0.3 2.0 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS00530 +0.3 2.2 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS08275 +0.3 3.0 hypothetical protein compare
MMP_RS00825 +0.3 2.3 fumarylacetoacetate hydrolase family protein compare
MMP_RS07330 +0.3 3.1 membrane protein compare
MMP_RS03440 +0.3 0.8 MoaD/ThiS family protein compare
MMP_RS08760 +0.3 1.5 hypothetical protein compare
MMP_RS07345 +0.3 1.7 glycine synthesis protein GlyXL (from data) compare
MMP_RS06575 +0.3 1.7 fluoride efflux transporter CrcB compare
MMP_RS01540 +0.3 1.6 DUF504 domain-containing protein compare
MMP_RS05580 +0.3 2.8 glycosyltransferase compare
MMP_RS01420 +0.3 1.4 hypothetical protein compare
MMP_RS08310 +0.3 1.2 TMEM165/GDT1 family protein compare
MMP_RS08580 +0.3 2.2 flagellin compare
MMP_RS06165 +0.3 2.5 ABC transporter permease compare
MMP_RS06480 +0.3 2.3 ABC transporter substrate-binding protein compare
MMP_RS08215 +0.3 1.8 DUF483 domain-containing protein compare
MMP_RS05635 +0.3 2.1 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06435 +0.3 2.4 CBS domain-containing protein compare
MMP_RS08705 +0.3 2.2 sulfopyruvate decarboxylase subunit beta compare
MMP_RS01580 +0.3 1.9 PQQ-binding-like beta-propeller repeat protein compare
MMP_RS07410 +0.3 2.2 4-demethylwyosine synthase TYW1 compare
MMP_RS07135 +0.3 2.5 coenzyme F420 hydrogenase subunit beta compare
MMP_RS06395 +0.3 1.6 ThiF family adenylyltransferase compare
MMP_RS06555 +0.3 1.5 cupin domain-containing protein compare
MMP_RS03405 +0.3 1.4 RNA 3'-terminal phosphate cyclase compare
MMP_RS01460 +0.3 1.7 hypothetical protein compare
MMP_RS02110 +0.3 1.2 hypothetical protein compare
MMP_RS04520 +0.3 1.4 nucleoside deaminase compare
MMP_RS08370 +0.3 0.4 cation:proton antiporter subunit C compare
MMP_RS03910 +0.3 1.3 hypothetical protein compare
MMP_RS06320 +0.3 1.9 hypothetical protein compare
MMP_RS06325 +0.3 0.8 hypothetical protein compare
MMP_RS08775 +0.3 1.5 methanogenesis marker 9 domain-containing protein compare
MMP_RS06550 +0.3 2.1 AMP-binding protein compare
MMP_RS03535 +0.3 1.1 helix-turn-helix transcriptional regulator compare
MMP_RS02490 +0.3 1.5 hypothetical protein compare
MMP_RS00975 +0.3 2.2 HD domain-containing protein compare
MMP_RS09035 +0.2 1.1 hypothetical protein compare
MMP_RS05975 +0.2 0.7 hypothetical protein compare
MMP_RS01270 +0.2 2.1 prepilin peptidase compare
MMP_RS01655 +0.2 0.9 DsrE family protein compare
MMP_RS04790 +0.2 1.8 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS08455 +0.2 1.4 multiprotein bridging factor aMBF1 compare
MMP_RS02020 +0.2 1.3 gamma-glutamylcyclotransferase compare
MMP_RS02475 +0.2 1.1 hypothetical protein compare
MMP_RS01575 +0.2 1.4 aldolase compare
MMP_RS02905 +0.2 1.2 2-thiouracil desulfurase family protein compare
MMP_RS06185 +0.2 1.6 thermonuclease family protein compare
MMP_RS00665 +0.2 1.2 hypothetical protein compare
MMP_RS05420 +0.2 1.4 DUF61 family protein compare
MMP_RS05715 +0.2 1.6 hypothetical protein compare
MMP_RS07680 +0.2 0.8 DUF366 family protein compare
MMP_RS00750 +0.2 0.7 fumarate hydratase compare
MMP_RS04630 +0.2 1.2 3'-5' exonuclease compare
MMP_RS03670 +0.2 1.1 DUF1890 domain-containing protein compare
MMP_RS01285 +0.2 1.8 hypothetical protein compare
MMP_RS02360 +0.2 1.5 hypothetical protein compare
MMP_RS05345 +0.2 1.2 hypothetical protein compare
MMP_RS02870 +0.2 1.4 hypothetical protein compare
MMP_RS00140 +0.2 1.1 DUF192 domain-containing protein compare
MMP_RS02045 +0.2 0.7 tRNA-Met compare
MMP_RS07435 +0.2 0.6 GMP synthase subunit A compare
MMP_RS02550 +0.2 1.0 helix-turn-helix transcriptional regulator compare
MMP_RS08930 +0.2 0.6 hypothetical protein compare
MMP_RS06155 +0.2 0.9 DUF4186 domain-containing protein compare
MMP_RS01975 +0.2 1.8 hypothetical protein compare
MMP_RS02510 +0.2 1.2 site-specific integrase compare
MMP_RS03550 +0.2 0.8 DUF2124 domain-containing protein compare
MMP_RS05790 +0.2 1.2 HDIG domain-containing protein compare
MMP_RS08945 +0.2 1.5 hypothetical protein compare
MMP_RS00535 +0.2 1.1 TIGR00375 family protein compare
MMP_RS01745 +0.2 1.3 AMP phosphorylase compare
MMP_RS06130 +0.2 0.8 peptidylprolyl isomerase compare
MMP_RS00145 +0.2 1.6 ATP-dependent Clp protease proteolytic subunit compare
MMP_RS01185 +0.2 1.2 hypothetical protein compare
MMP_RS05940 +0.2 1.0 corrinoid protein compare
MMP_RS03250 +0.2 1.2 MJ1244 family protein compare
MMP_RS01165 +0.2 1.1 DUF434 domain-containing protein compare
MMP_RS07130 +0.2 1.3 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS04490 +0.2 1.6 CBS domain-containing protein compare
MMP_RS01260 +0.2 1.1 HDIG domain-containing protein compare
MMP_RS03280 +0.2 1.3 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS01490 +0.2 1.2 tetratricopeptide repeat protein compare
MMP_RS06300 +0.2 1.4 ABC transporter substrate-binding protein compare
MMP_RS02895 +0.2 1.0 DHH family phosphoesterase compare
MMP_RS01650 +0.2 0.4 sulfurtransferase TusA family protein compare
MMP_RS05695 +0.2 1.4 phospholipase D-like domain-containing protein compare
MMP_RS05865 +0.2 1.1 hypothetical protein compare
MMP_RS03420 +0.2 0.7 acetolactate synthase small subunit compare
MMP_RS01515 +0.2 1.3 PINc/VapC family ATPase compare
MMP_RS06875 +0.2 1.1 FAD-dependent oxidoreductase compare
MMP_RS06055 +0.2 1.4 peroxiredoxin compare
MMP_RS01955 +0.2 0.5 hypothetical protein compare
MMP_RS04435 +0.2 1.4 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS06605 +0.2 1.3 DUF5814 domain-containing protein compare
MMP_RS06495 +0.2 0.5 YkgJ family cysteine cluster protein compare
MMP_RS03120 +0.2 1.1 hypothetical protein compare
MMP_RS01140 +0.2 1.0 molybdate ABC transporter permease subunit compare
MMP_RS01570 +0.2 0.5 hypothetical protein compare
MMP_RS07900 +0.2 0.5 YeeE/YedE family protein compare
MMP_RS07840 +0.2 0.8 ribonuclease III compare
MMP_RS03235 +0.2 1.0 tRNA pseudouridine(13) synthase TruD compare
MMP_RS02395 +0.2 1.3 hypothetical protein compare
MMP_RS06490 +0.2 0.9 hypothetical protein compare
MMP_RS00380 +0.2 1.2 P-II family nitrogen regulator compare
MMP_RS02645 +0.2 1.2 ArsR family transcriptional regulator compare
MMP_RS07855 +0.2 1.1 class I SAM-dependent methyltransferase compare
MMP_RS05365 +0.2 0.7 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS05455 +0.2 1.2 DUF167 domain-containing protein compare
MMP_RS05110 +0.2 1.3 16S ribosomal RNA methyltransferase A compare
MMP_RS05170 +0.2 1.3 lysine exporter LysO family protein compare
MMP_RS03765 +0.2 1.3 CopG family ribbon-helix-helix protein compare
MMP_RS06465 +0.2 1.3 NERD domain-containing protein compare
MMP_RS05945 +0.2 0.9 CBS domain-containing protein compare
MMP_RS04480 +0.2 1.4 lysine 2 3-aminomutase compare
MMP_RS00555 +0.2 1.0 MFS transporter compare
MMP_RS00285 +0.1 0.9 TIGR04013 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS00240 +0.1 1.3 type II secretion system F family protein compare
MMP_RS05995 +0.1 1.3 FprA family A-type flavoprotein compare
MMP_RS08755 +0.1 1.2 sodium:solute symporter family protein compare
MMP_RS07925 +0.1 0.8 haloacid dehalogenase compare
MMP_RS08975 +0.1 1.0 hypothetical protein compare
MMP_RS02810 +0.1 0.9 hypothetical protein compare
MMP_RS08640 +0.1 1.3 TIM barrel protein compare
MMP_RS01290 +0.1 1.2 class III signal peptide-containing protein compare
MMP_RS02955 +0.1 0.8 DJ-1/PfpI family protein compare
MMP_RS04985 +0.1 0.6 DUF2180 family protein compare
MMP_RS08890 +0.1 1.3 glycosyltransferase family 4 protein compare
MMP_RS00630 +0.1 0.9 ECF transporter S component compare
MMP_RS02650 +0.1 1.0 flavodoxin family protein compare
MMP_RS03800 +0.1 0.8 hypothetical protein compare
MMP_RS07180 +0.1 0.9 DEAD/DEAH box helicase compare
MMP_RS02685 +0.1 1.0 molybdate ABC transporter substrate-binding protein compare
MMP_RS08485 +0.1 1.2 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS00865 +0.1 0.9 SLC13 family permease compare
MMP_RS04105 +0.1 0.8 MarR family transcriptional regulator compare
MMP_RS02495 +0.1 0.6 hypothetical protein compare
MMP_RS07905 +0.1 0.8 DUF3343 domain-containing protein compare
MMP_RS08990 +0.1 0.7 hypothetical protein compare
MMP_RS06655 +0.1 1.2 glycoside hydrolase family 15 protein compare
MMP_RS05435 +0.1 1.0 5'/3'-nucleotidase SurE compare
MMP_RS01295 +0.1 1.1 hypothetical protein compare
MMP_RS02500 +0.1 0.8 minichromosome maintenance protein MCM compare
MMP_RS04440 +0.1 1.0 nitrogenase iron protein compare
MMP_RS09030 +0.1 0.9 hypothetical protein compare
MMP_RS03790 +0.1 1.1 hypothetical protein compare
MMP_RS00130 +0.1 0.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS00040 +0.1 0.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08085 +0.1 1.1 hypothetical protein compare
MMP_RS08245 +0.1 0.9 DUF4013 domain-containing protein compare
MMP_RS01885 +0.1 0.9 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01635 +0.1 1.0 thiamine pyrophosphate-dependent enzyme compare
MMP_RS07550 +0.1 1.0 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS01660 +0.1 0.8 hypothetical protein compare
MMP_RS06570 +0.1 0.5 DUF190 domain-containing protein compare
MMP_RS02585 +0.1 1.2 methyl-accepting chemotaxis protein compare
MMP_RS01065 +0.1 1.1 alpha/beta hydrolase compare
MMP_RS02300 +0.1 0.7 NAD(P)H-dependent oxidoreductase compare
MMP_RS08620 +0.1 0.7 flagellar accessory protein FlaH compare
MMP_RS04815 +0.1 0.9 chemotaxis protein CheD compare
MMP_RS02690 +0.1 0.9 FmdE family protein compare
MMP_RS08595 +0.1 0.2 flagellar protein C compare
MMP_RS05900 +0.1 0.8 tetratricopeptide repeat protein compare
MMP_RS01160 +0.1 0.9 DMT family transporter compare
MMP_RS02520 +0.1 1.1 hypothetical protein compare
MMP_RS01945 +0.1 0.7 DUF4350 domain-containing protein compare
MMP_RS02225 +0.1 0.7 carbohydrate kinase family protein compare
MMP_RS01275 +0.1 0.8 class III signal peptide-containing protein compare
MMP_RS07800 +0.1 1.0 ATP-binding cassette domain-containing protein compare
MMP_RS01280 +0.1 1.0 DUF515 domain-containing protein compare
MMP_RS02025 +0.1 1.0 DNA-directed DNA polymerase compare
MMP_RS01315 +0.1 1.1 DUF2341 domain-containing protein compare
MMP_RS08475 +0.1 1.0 ABC transporter permease compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium cyanide across organisms