Experiment set5H25 for Shewanella oneidensis MR-1

Compare to:

L-Alanine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
SO0229 tufA +8.3 18.8 translation elongation factor Tu (NCBI ptt file) compare
SO0217 tufB +7.8 16.7 translation elongation factor Tu (NCBI ptt file) compare
SO_t008 tRNA-Thr-1 +7.2 14.2 tRNA-Thr (RefSeq) compare
SO3770 +7.0 12.2 conserved hypothetical protein TIGR00153 (NCBI ptt file) compare
SO3771 +6.3 22.7 phosphate transporter, putative (NCBI ptt file) compare
SO0359 spoT +5.4 13.5 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) compare
SO3189 +5.3 38.0 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO0163 hslO +4.5 25.8 chaperonin HslO (NCBI ptt file) compare
SO0949 brnQ +4.4 29.2 branched-chain amino acid transport system II carrier protein BrnQ (NCBI ptt file) compare
SO2248 sdaA +4.3 10.8 L-serine dehydratase 1 (NCBI ptt file) compare
SO0605 hflK +4.0 19.9 hflK protein (NCBI ptt file) compare
SO2832 +3.9 22.5 conserved hypothetical protein (NCBI ptt file) compare
SO1665 galU +3.7 20.9 UTP-glucose-1-phosphate uridylyltransferase (NCBI ptt file) compare
SO0606 hflC +3.6 8.9 hflC protein (NCBI ptt file) compare
SO3171 +3.6 28.8 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO4626 bioH +3.4 20.9 bioH protein (NCBI ptt file) compare
SO2339 +3.4 19.8 alpha keto acid dehydrogenase complex, E1 component, alpha subunit (NCBI ptt file) compare
SO2340 +3.4 25.6 alpha keto acid dehydrogenase complex, E1 component, beta subunit (NCBI ptt file) compare
SO1784 feoB +3.3 7.9 ferrous iron transport protein B (NCBI ptt file) compare
SO2738 bioC +3.3 5.4 biotin synthesis protein BioC (NCBI ptt file) compare
SO2916 pta +3.1 17.2 phosphate acetyltransferase (NCBI ptt file) compare
SO3745 rfaE +3.0 20.0 ADP-heptose synthase (NCBI ptt file) compare
SO3174 +3.0 26.8 glycosyl transferase, group 1 family protein (NCBI ptt file) compare
SO4678 +3.0 18.8 heptosyl transferase, glycosyltransferase family 9 protein (NCBI ptt file) compare
SO2341 +3.0 19.0 alpha keto acid dehydrogenase complex, E2 component (NCBI ptt file) compare
SO3179 +2.9 25.3 lipopolysaccharide biosynthesis polymerase, putative (NCBI ptt file) compare
SO2739.1 +2.9 3.5 hypothetical protein (NCBI ptt file) compare
SO4197 menG-2 +2.9 5.0 S-adenosylmethionine:2-demethylmenaquinone methyltransferase (NCBI ptt file) compare
SO3269 +2.8 19.0 cytidylyltransferase domain protein (NCBI ptt file) compare
SO3122 +2.7 15.5 sodium/dicarboxylate symporter (NCBI ptt file) compare
SO4675 +2.7 19.4 transcriptional regulator, TetR family (NCBI ptt file) compare
SO2602 +2.7 5.3 hypothetical Activator of ProP osmoprotectant transporter (NCBI ptt file) compare
SO3268 +2.6 21.2 alpha amylase domain protein (NCBI ptt file) compare
SO2629 icd +2.6 16.8 isocitrate dehydrogenase, NADP-dependent (NCBI ptt file) compare
SO3109 +2.6 5.9 conserved hypothetical protein (NCBI ptt file) compare
SO1052 pit +2.6 18.8 low-affinity inorganic phosphate transporter (NCBI ptt file) compare
SOA0014 +2.6 8.5 hypothetical protein (NCBI ptt file) compare
SO1796 lon +2.5 13.5 ATP-dependent protease La (NCBI ptt file) compare
SO1819 dinG +2.4 14.0 ATP-dependent helicase DinG (NCBI ptt file) compare
SO2628 cspD +2.4 9.7 stress response protein CspD (NCBI ptt file) compare
SO1669 tyrR +2.4 12.4 transcriptional regulatory protein TyrR (NCBI ptt file) compare
SO1801 sapF +2.4 9.6 peptide ABC transporter, ATP-binding protein (NCBI ptt file) compare
SO1196 rrmJ +2.3 5.8 ribosomal RNA large subunit methyltransferase J (NCBI ptt file) compare
SO2739 bioF +2.3 10.6 8-amino-7-oxononanoate synthase (NCBI ptt file) compare
SO4658 +2.3 14.6 conserved hypothetical protein (NCBI ptt file) compare
SO_2754 +2.3 6.0 no description compare
SO_A0174 +2.2 5.2 hypothetical protein (NCBI) compare
SO3178 +2.2 20.1 hypothetical protein (NCBI ptt file) compare
SO2753.2 +2.2 7.9 hypothetical sodium-type flagellar protein MotY (NCBI ptt file) compare
SO2237 ptsI +2.2 5.8 phosphoenolpyruvate-protein phosphotransferase (NCBI ptt file) compare
SO2088 +2.2 7.0 lipid A biosynthesis acyltransferase, putative (NCBI ptt file) compare
SO4320 aggA +2.1 8.5 agglutination protein (NCBI ptt file) compare
SO2537 +2.1 14.0 sodium/hydrogen exchanger family protein (NCBI ptt file) compare
SO3184 +2.1 19.5 conserved hypothetical protein (NCBI ptt file) compare
SO0298 gmhA +2.1 6.4 phosphoheptose isomerase (NCBI ptt file) compare
SO1530 pomB +2.1 7.2 sodium-driven polar flagellar protein PomB (NCBI ptt file) compare
SO0345 prpB +2.1 3.6 methylisocitrate lyase (NCBI ptt file) compare
SO3188 rfbB +2.1 14.4 dTDP-glucose 4,6-dehydratase (NCBI ptt file) compare
SO4318 rtxB +2.1 14.6 toxin secretion ATP-binding protein (NCBI ptt file) compare
SO4351 +2.1 14.9 CBS domain protein (NCBI ptt file) compare
SO1522 +2.0 10.9 D,L-lactate/pyruvate symporter LctP2 (from data) compare
SO3182 +2.0 14.4 acetyltransferase, GNAT family (NCBI ptt file) compare
SOA0010 +2.0 7.3 conserved hypothetical protein (NCBI ptt file) compare
SO3262 ilvB +2.0 16.0 acetolactate synthase isozyme I, large subunit (NCBI ptt file) compare
SOA0171 +2.0 8.2 hypothetical protein (NCBI ptt file) compare
SOA0011 +2.0 8.2 conserved hypothetical protein (NCBI ptt file) compare
SO3227 fliG +2.0 12.4 flagellar motor switch protein FliG (NCBI ptt file) compare
SO1805 sapA +2.0 4.0 peptide ABC transporter, periplasmic peptide-binding protein (NCBI ptt file) compare
SO4319 +1.9 16.3 HlyD family secretion protein (NCBI ptt file) compare
SO4680 +1.9 13.3 conserved hypothetical protein (NCBI ptt file) compare
SO3180 +1.9 16.9 glycosyl transferase, group 2 family protein (NCBI ptt file) compare
SOA0002 +1.9 18.5 type II restriction-modification system activator, putative (NCBI ptt file) compare
SOA0056 +1.9 4.1 hypothetical protein (NCBI ptt file) compare
SO3183 +1.8 16.2 perosamine synthetase-related protein (NCBI ptt file) compare
SO1803 sapC +1.8 5.2 peptide ABC transporter, permease protein (NCBI ptt file) compare
SO3516 +1.8 11.7 transcriptional regulator, LacI family (NCBI ptt file) compare
SOA0041 +1.8 17.4 transcriptional regulator, PemK family (NCBI ptt file) compare
SO3229 fliE +1.8 3.3 flagellar hook-basal body complex protein FliE (NCBI ptt file) compare
SOA0008 +1.8 12.0 hypothetical protein (NCBI ptt file) compare
SO1290 +1.7 8.6 conserved hypothetical protein TIGR00023 (NCBI ptt file) compare
SOA0003 +1.7 16.5 type II restriction endonuclease, putative (NCBI ptt file) compare
SOA0012 umuC +1.7 11.2 umuC protein (NCBI ptt file) compare
SO3192 +1.7 5.0 conserved hypothetical protein (NCBI ptt file) compare
SO2853 +1.7 9.0 3-oxoacyl-(acyl-carrier-protein) synthase III, putative (NCBI ptt file) compare
SO3176 +1.7 15.6 glycosyl transferase, group 1 family protein (NCBI ptt file) compare
SO3245 flgF +1.7 9.6 flagellar basal-body rod protein FlgF (NCBI ptt file) compare
SO3215 flhB +1.7 5.8 flagellar biosynthetic protein FlhB (NCBI ptt file) compare
SO3210 fliA +1.7 3.8 RNA polymerase sigma-27 factor (NCBI ptt file) compare
SO4679 +1.7 8.7 glycosyl transferase, group 1 family protein (NCBI ptt file) compare
SOA0013 umuD +1.7 7.2 umuD protein (VIMSS) compare
SO3689 +1.7 6.0 sigma-54 dependent nitrogen response regulator (NCBI ptt file) compare
SO3228 fliF +1.7 10.6 flagellar M-ring protein FliF (NCBI ptt file) compare
SO3258 +1.7 9.8 conserved hypothetical protein (NCBI ptt file) compare
SO3173 +1.7 12.7 UDP-galactose 4-epimerase, putative (NCBI ptt file) compare
SO3190 +1.6 11.5 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO_A0007 +1.6 10.0 hypothetical protein (NCBI) compare
SO3986 lysC +1.6 8.4 aspartokinase III, lysine-sensitive (NCBI ptt file) compare
SO1551 +1.6 11.9 GGDEF domain protein (NCBI ptt file) compare
SO3244 flgG +1.6 11.5 flagellar basal-body rod protein FlgG (NCBI ptt file) compare
SO3953 +1.6 5.8 conserved hypothetical protein TIGR00056 (NCBI ptt file) compare
SO_A0009 +1.6 4.4 hypothetical protein (NCBI) compare
SO3177 +1.6 13.0 formyl transferase domain protein (NCBI ptt file) compare
SO3185 +1.5 13.4 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO4002 +1.5 13.4 sensory transduction histidine kinase (NCBI ptt file) compare
SO4727 +1.5 8.0 conserved hypothetical protein (NCBI ptt file) compare
SO3265 +1.5 10.2 conserved hypothetical protein (NCBI ptt file) compare
SO_t037 tRNA-Pro-4 +1.5 4.2 tRNA-Pro (RefSeq) compare
SO4462 +1.5 7.1 hypothetical protein (NCBI ptt file) compare
SO4351.1 +1.5 5.8 amino acid ABC transporter protein (NCBI) compare
SO_3068 +1.5 2.4 no description compare
SO0347 +1.5 7.2 acyltransferase family protein (NCBI ptt file) compare
SOA0172 +1.5 7.5 site-specific recombinase, resolvase family (NCBI ptt file) compare
SO2336 pgm +1.5 3.8 phosphoglucomutase, alpha-D-glucose phosphate-specific (NCBI ptt file) compare
SO4055 metL +1.5 11.9 aspartokinase II/homoserine dehydrogenase, methionine-sensitive (NCBI ptt file) compare
SO3175 asnB-2 +1.4 13.4 asparagine synthetase, glutamine-hydrolyzing (NCBI ptt file) compare
SO4094 cafA +1.4 6.2 ribonuclease G (NCBI ptt file) compare
SO3472 +1.4 8.5 ABC transporter, ATP-binding protein (NCBI ptt file) compare
SO4112 mshL +1.4 8.1 MSHA biogenesis protein MshL (NCBI ptt file) compare
SO1371 +1.4 4.9 conserved hypothetical protein (NCBI ptt file) compare
SO2907 +1.4 9.3 TonB-dependent receptor domain protein (NCBI ptt file) compare
SOA0004 +1.4 7.6 type II DNA modification methyltransferase (NCBI ptt file) compare
SO4072 yliG +1.4 7.7 MiaB-like putative RNA modifying enzyme YliG (NCBI ptt file) compare
SO2638 ldh +1.4 4.7 leucine dehydrogenase (NCBI ptt file) compare
SO2427 +1.4 9.6 TonB-dependent receptor, putative (NCBI ptt file) compare
SO4718 +1.4 7.4 sigma-54 dependent response regulator (NCBI ptt file) compare
SO4113 mshK +1.4 3.0 MSHA biogenesis protein MshK (NCBI ptt file) compare
SO0407 +1.4 7.0 ATP-dependent RNA helicase, DEAD box family (NCBI ptt file) compare
SO3912 +1.4 9.3 TIM-barrel protein, yjbN family (NCBI ptt file) compare
SO4702 gor +1.3 10.4 glutathione reductase (NCBI ptt file) compare
SO3181 +1.3 4.8 polysaccharide biosynthesis domain protein (NCBI ptt file) compare
SO0206 trmA +1.3 8.8 tRNA (uracil-5-)-methyltransferase (NCBI ptt file) compare
SO3172 +1.3 3.3 galactosyl transferase (NCBI ptt file) compare
SO2176 +1.3 3.5 conserved hypothetical protein (NCBI ptt file) compare
SO0542 +1.3 7.8 conserved hypothetical protein (NCBI ptt file) compare
SO4687 ugd +1.3 10.2 UDP-glucose 6-dehydrogenase (NCBI ptt file) compare
SO3126 ogt +1.3 2.3 methylated-DNA--protein-cysteine methyltransferase (NCBI ptt file) compare
SO2421 ansA +1.3 3.9 L-asparaginase I (NCBI ptt file) compare
SO4686 +1.3 7.1 NAD dependent epimerase/dehydratase family protein (NCBI ptt file) compare
SO1664 galE +1.2 7.5 UDP-glucose 4-epimerase (NCBI ptt file) compare
SOA0005 +1.2 6.9 hypothetical protein (NCBI ptt file) compare
SO3900 +1.2 3.0 yqiA-like hydrolase, affects the cell envelope (from data) compare
SO0364 +1.2 7.3 conserved hypothetical protein (NCBI ptt file) compare
SO4109 mshE +1.2 8.2 MSHA biogenesis protein MshE (NCBI ptt file) compare
SO_A0006 +1.2 7.5 ParA family protein (NCBI) compare
SO3324 +1.2 5.3 acetyltransferase, GNAT family (NCBI ptt file) compare
SO3592 +1.2 8.1 conserved hypothetical protein (NCBI ptt file) compare
SO1185 +1.2 7.3 conserved hypothetical protein TIGR00092 (NCBI ptt file) compare
SO0198 +1.2 6.0 transcriptional regulator, TetR family (NCBI ptt file) compare
SO1505 +1.2 8.8 transporter, putative (NCBI ptt file) compare
SO4114 mshJ +1.2 3.1 MSHA biogenesis protein MshJ (NCBI ptt file) compare
SO0558 smtA +1.2 6.7 smtA protein (NCBI ptt file) compare
SO3936 motX +1.1 2.6 sodium-type flagellar protein MotX (NCBI ptt file) compare
SO3987 +1.1 6.8 conserved hypothetical protein (NCBI ptt file) compare
SO4029 +1.1 4.7 transporter, putative (NCBI ptt file) compare
SO4317 +1.1 9.8 RTX toxin, putative (NCBI ptt file) compare
SO3855 sfcA +1.1 6.9 malate oxidoreductase (NCBI ptt file) compare
SO2338 astE +1.1 4.7 succinylglutamate desuccinylase (NCBI ptt file) compare
SO3254 flgM +1.1 4.4 negative regulator of flagellin synthesis FlgM (NCBI ptt file) compare
SO_3098 +1.1 2.5 no description compare
SO_4115 +1.1 7.4 no description compare
SO4742 +1.1 2.7 transcriptional regulator, DeoR family (NCBI ptt file) compare
SO0452 trxC +1.1 2.1 thioredoxin 2 (NCBI ptt file) compare
SO0045 +1.1 2.2 Rrf2 family protein (NCBI ptt file) compare
SO2614 +1.1 2.2 conserved hypothetical protein TIGR00247 (NCBI ptt file) compare
SOA0042 +1.1 9.9 hypothetical protein (NCBI ptt file) compare
SO0333 dsbA +1.1 2.6 thiol:disulfide interchange protein DsbA (NCBI ptt file) compare
SO3257 +1.1 3.7 conserved hypothetical protein (NCBI ptt file) compare
SO1678 mmsA +1.1 5.8 methylmalonate-semialdehyde dehydrogenase (NCBI ptt file) compare
SO1679 +1.1 5.2 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
SO0191 cysQ-1 +1.1 5.6 cysQ protein (NCBI ptt file) compare
SO1065 fkpA +1.1 6.3 FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (NCBI ptt file) compare
SO2858 +1.1 2.2 conserved hypothetical protein (NCBI ptt file) compare
SO2476 +1.1 4.2 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO3080 +1.0 6.2 hemK family protein (NCBI ptt file) compare
SOA0059 +1.0 2.1 conserved hypothetical protein (NCBI ptt file) compare
SO0417 +1.0 3.5 pilin, putative (NCBI ptt file) compare
SO0026 +1.0 3.4 transcriptional regulator, ArsR family (NCBI ptt file) compare
SO4114.2 +1.0 7.0 hypothetical biogenesis protein MshI (NCBI ptt file) compare
SO3690 +1.0 5.8 ABC transporter, permease protein (NCBI ptt file) compare
SO4641 +1.0 1.8 conserved hypothetical protein (NCBI ptt file) compare
SO2887 dsbB +1.0 4.1 disulfide bond formation protein b (NCBI ptt file) compare
SO1818 +1.0 6.3 conserved hypothetical protein (NCBI ptt file) compare
SO3224 fliJ +1.0 6.3 flagellar protein FliJ (NCBI ptt file) compare
SO2838 +1.0 2.1 ATP-dependent RNA helicase, DEAD box family (NCBI ptt file) compare
SO1846 +1.0 4.3 hypothetical protein (NCBI ptt file) compare
SO3256 +1.0 2.7 conserved hypothetical protein (NCBI ptt file) compare
SO2683 +1.0 3.2 hypothetical protein (NCBI ptt file) compare
SO2101 +1.0 1.4 lipoprotein, putative (NCBI ptt file) compare
SO3186 rfbA +1.0 4.4 glucose-1-phosphate-thymidylyltransferase (NCBI ptt file) compare
SO1851 +1.0 7.5 conserved hypothetical protein (NCBI ptt file) compare
SO0697 cutA +1.0 1.6 periplasmic divalent cation tolerance protein CutA (NCBI ptt file) compare
SO0618 astA +1.0 6.3 arginine N-succinyltransferase (NCBI ptt file) compare
SO3014 +1.0 2.6 conserved hypothetical protein (NCBI ptt file) compare
SO0640 +1.0 6.1 alcohol dehydrogenase, zinc-containing (NCBI ptt file) compare
SO2477 +1.0 5.6 alcohol dehydrogenase, iron-containing (NCBI ptt file) compare
SO2769 +0.9 3.9 conserved hypothetical protein (NCBI ptt file) compare
SO2912 pflB +0.9 6.2 formate acetyltransferase (NCBI ptt file) compare
SO1948 +0.9 6.0 sodium:dicarboxylate symporter family protein (NCBI ptt file) compare
SO1469 +0.9 3.2 transcriptional regulator, Cro/CI family (NCBI ptt file) compare
SO4162 hslV +0.9 4.9 ATP-dependent protease HslV (NCBI ptt file) compare


Specific Phenotypes

For 42 genes in this experiment

For nitrogen source L-Alanine in Shewanella oneidensis MR-1

For nitrogen source L-Alanine across organisms