Experiment set3IT066 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS01650		+1.4	2.6	sulfurtransferase TusA family protein
MMP_RS06975		+0.8	3.4	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS00675		+0.7	1.3	nitroreductase family protein
MMP_RS03300		+0.6	1.0	TOBE domain-containing protein
MMP_RS07345		+0.6	3.7	glycine synthesis protein GlyXL (from data)
MMP_RS07895		+0.5	2.8	cytochrome c
MMP_RS07120		+0.4	3.4	coenzyme F420 hydrogenase subunit alpha
MMP_RS02605		+0.4	0.7	MotA/TolQ/ExbB proton channel family protein
MMP_RS09025		+0.4	1.0	hypothetical protein
MMP_RS08995		+0.4	1.2	hypothetical protein
MMP_RS07860		+0.4	0.5	hypothetical protein
MMP_RS08580		+0.4	2.3	flagellin
MMP_RS08980		+0.4	2.5	hypothetical protein
MMP_RS04205		+0.4	1.7	carboxymuconolactone decarboxylase family protein
MMP_RS08310		+0.4	1.5	TMEM165/GDT1 family protein
MMP_RS08615		+0.4	1.1	flagellar protein G
MMP_RS07835		+0.4	2.3	TldD/PmbA family protein
MMP_RS01260		+0.4	2.0	HDIG domain-containing protein
MMP_RS05985		+0.4	1.1	hypothetical protein
MMP_RS05355		+0.4	0.6	hypothetical protein
MMP_RS00545		+0.4	2.1	XRE family transcriptional regulator
MMP_RS08620		+0.3	2.4	flagellar accessory protein FlaH
MMP_RS05975		+0.3	1.0	hypothetical protein
MMP_RS08160		+0.3	2.2	EamA family transporter
MMP_RS01435		+0.3	1.7	DMT family transporter
MMP_RS01570		+0.3	1.0	hypothetical protein
MMP_RS06930		+0.3	2.2	MBL fold metallo-hydrolase
MMP_RS06710		+0.3	2.4	selenium-binding protein
MMP_RS06965		+0.3	2.2	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS07130		+0.3	2.8	coenzyme F420 hydrogenase subunit gamma
MMP_RS01100		+0.3	1.0	ABC transporter ATP-binding protein
MMP_RS08260		+0.3	2.5	DUF99 family protein
MMP_RS00105		+0.3	2.2	hypothetical protein
MMP_RS06155		+0.3	1.5	DUF4186 domain-containing protein
MMP_RS07925		+0.3	1.9	haloacid dehalogenase
MMP_RS00395		+0.3	1.0	MGMT family protein
MMP_RS07125		+0.3	1.9	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06610		+0.3	1.3	DUF2334 domain-containing protein
MMP_RS02995		+0.3	2.1	acyl-CoA thioesterase
MMP_RS07135		+0.3	2.2	coenzyme F420 hydrogenase subunit beta
MMP_RS06540		+0.3	1.2	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS08325		+0.3	2.3	hypothetical protein
MMP_RS08275		+0.3	2.0	hypothetical protein
MMP_RS01430		+0.3	2.1	mechanosensitive ion channel family protein
MMP_RS02310		+0.3	1.0	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS07850		+0.3	1.4	prephenate dehydratase
MMP_RS01965		+0.3	1.3	DUF1616 domain-containing protein
MMP_RS08390		+0.3	1.6	DUF5400 domain-containing protein
MMP_RS08205		+0.3	2.2	stage II sporulation protein M
MMP_RS06005		+0.3	1.5	heavy-metal-associated domain-containing protein
MMP_RS07100		+0.3	2.3	hypothetical protein
MMP_RS00285		+0.3	1.9	TIGR04013 family B12-binding domain/radical SAM domain-containing protein
MMP_RS08480		+0.3	2.2	molybdate ABC transporter substrate-binding protein
MMP_RS08835		+0.3	1.6	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS08380		+0.2	2.1	phosphatase PAP2 family protein
MMP_RS03465		+0.2	0.5	adenine phosphoribosyltransferase
MMP_RS07650		+0.2	2.2	TldD/PmbA family protein
MMP_RS02745		+0.2	0.9	hypothetical protein
MMP_RS06520		+0.2	1.3	DUF1786 domain-containing protein
MMP_RS01630		+0.2	1.7	N-glycosylase/DNA lyase
MMP_RS05535		+0.2	1.2	hypothetical protein
MMP_RS08245		+0.2	1.8	DUF4013 domain-containing protein
MMP_RS04015		+0.2	0.7	hypothetical protein
MMP_RS08485		+0.2	1.6	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS06555		+0.2	1.2	cupin domain-containing protein
MMP_RS07590		+0.2	1.9	hypothetical protein
MMP_RS05715		+0.2	1.8	hypothetical protein
MMP_RS08090		+0.2	1.1	hypothetical protein
MMP_RS05455		+0.2	1.7	DUF167 domain-containing protein
MMP_RS05790		+0.2	1.4	HDIG domain-containing protein
MMP_RS02370		+0.2	1.3	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS00540		+0.2	1.5	PLP-dependent aminotransferase family protein
MMP_RS04030		+0.2	1.6	hypothetical protein
MMP_RS00055		+0.2	1.6	DUF2254 domain-containing protein
MMP_RS01785		+0.2	1.3	hypothetical protein
MMP_RS08315		+0.2	1.0	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS08130		+0.2	1.6	IGHMBP2 family helicase
MMP_RS03890		+0.2	1.3	DUF2540 domain-containing protein
MMP_RS00735		+0.2	1.0	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS02675		+0.2	0.8	hypothetical protein
MMP_RS07775		+0.2	1.3	alanine dehydrogenase
MMP_RS03765		+0.2	1.3	CopG family ribbon-helix-helix protein
MMP_RS05675		+0.2	0.9	phosphate ABC transporter ATP-binding protein PstB
MMP_RS01090		+0.2	1.5	ABC transporter substrate-binding protein
MMP_RS01075		+0.2	0.3	hypothetical protein
MMP_RS07145		+0.2	1.5	AmmeMemoRadiSam system protein B
MMP_RS00955		+0.2	1.6	coenzyme gamma-F420-2:alpha-L-glutamate ligase
MMP_RS07915		+0.2	1.1	DUF4870 domain-containing protein
MMP_RS05990		+0.2	1.2	DsrE family protein
MMP_RS04840		+0.2	1.3	response regulator
MMP_RS07805		+0.2	1.3	ABC transporter permease
MMP_RS07770		+0.2	1.3	alanine racemase
MMP_RS08625		+0.2	1.6	type II/IV secretion system ATPase subunit
MMP_RS06250		+0.2	1.2	hypothetical protein
MMP_RS07910		+0.2	1.2	NAD(P)H-hydrate dehydratase
MMP_RS03790		+0.2	1.5	hypothetical protein
MMP_RS01105		+0.2	1.4	hypothetical protein
MMP_RS08700		+0.2	1.4	hypothetical protein
MMP_RS06655		+0.2	1.4	glycoside hydrolase family 15 protein
MMP_RS05835		+0.2	0.3	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS08610		+0.2	1.4	flagellar protein F
MMP_RS05660		+0.2	1.2	phosphate ABC transporter substrate-binding protein
MMP_RS06910		+0.2	1.2	RlmF-related methyltransferase
MMP_RS03965		+0.2	0.7	hypothetical protein
MMP_RS09065		+0.2	1.6	hypothetical protein
MMP_RS08930		+0.2	0.7	hypothetical protein
MMP_RS08455		+0.2	1.3	multiprotein bridging factor aMBF1
MMP_RS00380		+0.2	0.9	P-II family nitrogen regulator
MMP_RS07155		+0.2	1.5	MFS transporter
MMP_RS03900		+0.2	1.3	minichromosome maintenance protein MCM
MMP_RS06495		+0.2	1.0	YkgJ family cysteine cluster protein
MMP_RS06665		+0.2	1.3	glycogen/starch synthase
MMP_RS09050		+0.2	0.8	CAP domain-containing protein
MMP_RS02320		+0.2	1.3	glutamate-cysteine ligase family protein
MMP_RS05980		+0.2	1.3	ferritin
MMP_RS06320		+0.2	1.1	hypothetical protein
MMP_RS03215		+0.2	1.3	MBL fold metallo-hydrolase
MMP_RS00690		+0.2	1.2	MBL fold metallo-hydrolase
MMP_RS06300		+0.2	1.4	ABC transporter substrate-binding protein
MMP_RS05970		+0.2	0.9	class II SORL domain-containing protein
MMP_RS07985		+0.2	1.5	nitroreductase family protein
MMP_RS01945		+0.2	1.1	DUF4350 domain-containing protein
MMP_RS08640		+0.2	1.5	TIM barrel protein
MMP_RS00085		+0.2	1.4	DNA cytosine methyltransferase
MMP_RS06150		+0.2	1.4	hypothetical protein
MMP_RS07640		+0.2	1.1	mechanosensitive ion channel family protein
MMP_RS06590		+0.2	0.6	GNAT family N-acetyltransferase
MMP_RS01855		+0.2	1.1	2-hydroxyacyl-CoA dehydratase family protein
MMP_RS07595		+0.2	1.5	hypothetical protein
MMP_RS06440		+0.2	1.3	CBS domain-containing protein
MMP_RS08850		+0.2	1.5	hypothetical protein
MMP_RS01080		+0.2	0.9	DUF2202 domain-containing protein
MMP_RS00795		+0.2	1.3	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS09060		+0.2	1.4	hypothetical protein
MMP_RS06575		+0.2	0.9	fluoride efflux transporter CrcB
MMP_RS06465		+0.2	1.3	NERD domain-containing protein
MMP_RS07140		+0.2	1.5	TIGR00341 family protein
MMP_RS08285		+0.2	1.3	serine/threonine protein kinase
MMP_RS03895		+0.2	0.8	hypothetical protein
MMP_RS04740		+0.2	0.9	DUF473 domain-containing protein
MMP_RS07800		+0.2	1.2	ATP-binding cassette domain-containing protein
MMP_RS07115		+0.2	1.1	MBL fold metallo-hydrolase
MMP_RS06560		+0.2	1.2	hypothetical protein
MMP_RS03820		+0.2	1.0	EamA family transporter
MMP_RS00800		+0.2	1.2	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01980		+0.1	1.2	trimeric intracellular cation channel family protein
MMP_RS08265		+0.1	0.9	rubrerythrin
MMP_RS06045		+0.1	1.0	DNA polymerase
MMP_RS08500		+0.1	0.7	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS07970		+0.1	0.8	hypothetical protein
MMP_RS05960		+0.1	1.1	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06140		+0.1	0.8	radical SAM protein
MMP_RS06305		+0.1	1.1	transporter substrate-binding domain-containing protein
MMP_RS07715		+0.1	1.0	YfcE family phosphodiesterase
MMP_RS02510		+0.1	1.1	site-specific integrase
MMP_RS06395		+0.1	0.7	ThiF family adenylyltransferase
MMP_RS00565		+0.1	0.9	CBS domain-containing protein
MMP_RS02590		+0.1	1.1	low molecular weight phosphatase family protein
MMP_RS00910		+0.1	1.1	2-phosphosulfolactate phosphatase
MMP_RS02705		+0.1	0.9	formylmethanofuran dehydrogenase subunit B
MMP_RS02295		+0.1	1.1	TatD family hydrolase
MMP_RS01095		+0.1	1.0	iron ABC transporter permease
MMP_RS07900		+0.1	0.5	YeeE/YedE family protein
MMP_RS08770		+0.1	0.8	hypothetical protein
MMP_RS05530		+0.1	1.1	signal peptide peptidase SppA
MMP_RS05780		+0.1	0.9	multidrug resistance efflux transporter family protein
MMP_RS01010		+0.1	1.1	DUF4352 domain-containing protein
MMP_RS00635		+0.1	0.7	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS00385		+0.1	1.2	P-II family nitrogen regulator
MMP_RS06325		+0.1	0.4	hypothetical protein
MMP_RS01975		+0.1	1.2	hypothetical protein
MMP_RS08175		+0.1	1.0	7-cyano-7-deazaguanine synthase
MMP_RS07560		+0.1	0.8	prefoldin subunit alpha
MMP_RS08830		+0.1	0.6	GTP-binding protein
MMP_RS08430		+0.1	1.0	HAD family hydrolase
MMP_RS08575		+0.1	1.2	hypothetical protein
MMP_RS07840		+0.1	0.7	ribonuclease III
MMP_RS08775		+0.1	0.7	methanogenesis marker 9 domain-containing protein
MMP_RS01145		+0.1	1.1	ABC transporter ATP-binding protein
MMP_RS06335		+0.1	0.8	HAD family hydrolase
MMP_RS05945		+0.1	0.7	CBS domain-containing protein
MMP_RS04520		+0.1	0.4	nucleoside deaminase
MMP_RS04165		+0.1	0.6	TetR/AcrR family transcriptional regulator
MMP_RS02020		+0.1	0.7	gamma-glutamylcyclotransferase
MMP_RS08475		+0.1	0.8	ABC transporter permease
MMP_RS00445		+0.1	1.1	7-carboxy-7-deazaguanine synthase QueE
MMP_RS00655		+0.1	0.5	hypothetical protein
MMP_RS07150		+0.1	0.7	MTH895/ArsE family thioredoxin-like protein
MMP_RS01420		+0.1	0.4	hypothetical protein
MMP_RS05110		+0.1	0.9	16S ribosomal RNA methyltransferase A
MMP_RS06070		+0.1	1.0	iron ABC transporter substrate-binding protein
MMP_RS01885		+0.1	0.7	Gfo/Idh/MocA family oxidoreductase
MMP_RS03395		+0.1	0.7	hypothetical protein
MMP_RS06055		+0.1	0.8	peroxiredoxin
MMP_RS02265		+0.1	0.8	nitroreductase family protein
MMP_RS02895		+0.1	0.6	DHH family phosphoesterase
MMP_RS07855		+0.1	1.0	class I SAM-dependent methyltransferase
MMP_RS02045		+0.1	0.3	tRNA-Met
MMP_RS05275		+0.1	1.0	AI-2E family transporter
MMP_RS05155		+0.1	0.6	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in rich t1 experiments