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Experiment set3IT036 for
Methanococcus maripaludis JJ
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formate McAA biotin dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.5
10.7
hypothetical protein
compare
MMJJ
_RS08130
+1.2
1.2
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS04005
+0.8
6.2
acetate--CoA ligase family protein
compare
MMJJ
_RS07750
+0.8
2.6
class III signal peptide-containing protein
compare
MMJJ
_RS03725
+0.8
2.8
sulfurtransferase TusA family protein
compare
MMJJ
_RS03585
+0.7
0.7
methanogenesis marker 6 protein
compare
MMJJ
_RS06680
+0.7
3.5
DUF366 family protein
compare
MMJJ
_RS03360
+0.6
1.2
hypothetical protein
compare
MMJJ
_RS06675
+0.5
4.1
TIGR01212 family radical SAM protein
compare
MMJJ
_RS04955
+0.5
3.4
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS07015
+0.5
0.7
PFL family protein
compare
MMJJ
_RS03775
+0.5
1.8
50S ribosomal protein L15e
compare
MMJJ
_RS08830
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS07235
+0.5
4.0
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS07220
+0.5
3.8
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS07225
+0.4
2.8
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS06735
+0.4
3.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS06440
+0.4
2.8
DUF4870 domain-containing protein
compare
MMJJ
_RS01070
+0.4
0.6
PadR family transcriptional regulator
compare
MMJJ
_RS08515
+0.4
1.9
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS05975
+0.4
2.5
sulfurtransferase TusA family protein
compare
MMJJ
_RS07890
+0.4
2.3
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS06460
+0.4
2.3
cytochrome c
compare
MMJJ
_RS06950
+0.4
2.8
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS02115
+0.4
2.9
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS01670
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS07920
+0.4
2.6
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07240
+0.4
3.2
MBL fold metallo-hydrolase
compare
MMJJ
_RS06385
+0.4
1.7
hypothetical protein
compare
MMJJ
_RS06190
+0.4
2.9
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS04375
+0.4
1.3
hypothetical protein
compare
MMJJ
_RS04340
+0.4
1.5
hypothetical protein
compare
MMJJ
_RS06455
+0.4
3.0
YeeE/YedE family protein
compare
MMJJ
_RS04545
+0.4
1.4
PadR family transcriptional regulator
compare
MMJJ
_RS02665
+0.4
1.1
methyl-accepting chemotaxis protein
compare
MMJJ
_RS06085
+0.4
1.9
proteasome assembly chaperone family protein
compare
MMJJ
_RS06210
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS07985
+0.4
1.5
hypothetical protein
compare
MMJJ
_RS06810
+0.3
2.9
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS09295
+0.3
0.4
hypothetical protein
compare
MMJJ
_RS07260
+0.3
2.1
PspC domain-containing protein
compare
MMJJ
_RS07795
+0.3
1.7
cupin domain-containing protein
compare
MMJJ
_RS03575
+0.3
1.9
NUDIX hydrolase
compare
MMJJ
_RS05525
+0.3
1.8
GTP-binding protein
compare
MMJJ
_RS01100
+0.3
0.6
helix-turn-helix domain-containing protein
compare
MMJJ
_RS07205
+0.3
1.4
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS07270
+0.3
2.3
ribonuclease HII
compare
MMJJ
_RS04105
+0.3
2.7
prepilin peptidase
compare
MMJJ
_RS06275
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS08100
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS08225
+0.3
1.5
peptidylprolyl isomerase
compare
MMJJ
_RS07025
+0.3
1.9
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS07765
+0.3
1.3
DMT family protein
compare
MMJJ
_RS01590
+0.3
0.8
adenine phosphoribosyltransferase
compare
MMJJ
_RS07210
+0.3
2.3
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS00745
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS06470
+0.3
2.1
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS03445
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS06205
+0.3
2.2
EamA family transporter
compare
MMJJ
_RS05765
+0.3
0.5
flagellar protein E
compare
MMJJ
_RS01010
+0.3
2.9
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS04350
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS06745
+0.3
1.7
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS06685
+0.3
2.5
S-layer protein
compare
MMJJ
_RS05685
+0.3
1.8
class III signal peptide-containing protein
compare
MMJJ
_RS06770
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS05390
+0.3
2.3
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS05915
+0.3
0.8
multiprotein bridging factor aMBF1
compare
MMJJ
_RS07230
+0.3
1.7
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07215
+0.3
2.3
TIGR00341 family protein
compare
MMJJ
_RS09065
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS01855
+0.3
2.0
MBL fold metallo-hydrolase
compare
MMJJ
_RS04815
+0.3
1.3
TIM barrel protein
compare
MMJJ
_RS00845
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS05040
+0.3
2.0
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS08305
+0.3
1.5
peroxiredoxin
compare
MMJJ
_RS02230
+0.3
2.2
hypothetical protein
compare
MMJJ
_RS09360
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS07800
+0.3
2.0
AMP-binding protein
compare
MMJJ
_RS00150
+0.3
1.5
DUF2180 family protein
compare
MMJJ
_RS08525
+0.3
1.6
peptidylprolyl isomerase
compare
MMJJ
_RS04215
+0.3
2.1
DMT family transporter
compare
MMJJ
_RS06790
+0.3
2.2
nucleotidyltransferase family protein
compare
MMJJ
_RS06585
+0.3
1.7
alanine racemase
compare
MMJJ
_RS06280
+0.3
1.9
hypothetical protein
compare
MMJJ
_RS07915
+0.3
1.4
CBS domain-containing protein
compare
MMJJ
_RS00145
+0.3
2.1
aquaporin family protein
compare
MMJJ
_RS08880
+0.3
1.2
IMPACT family protein
compare
MMJJ
_RS04635
+0.3
1.8
DUF367 family protein
compare
MMJJ
_RS07760
+0.3
1.3
GNAT family N-acetyltransferase
compare
MMJJ
_RS07495
+0.3
1.4
4Fe-4S binding protein
compare
MMJJ
_RS06515
+0.3
1.9
ribonuclease III
compare
MMJJ
_RS06765
+0.2
2.1
hypothetical protein
compare
MMJJ
_RS04295
+0.2
1.9
DUF2202 domain-containing protein
compare
MMJJ
_RS06500
+0.2
1.5
class I SAM-dependent methyltransferase
compare
MMJJ
_RS08165
+0.2
1.3
thermonuclease family protein
compare
MMJJ
_RS05350
+0.2
1.3
DUF192 domain-containing protein
compare
MMJJ
_RS03375
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS02895
+0.2
1.7
ATP-binding protein
compare
MMJJ
_RS03025
+0.2
1.9
Ig-like domain-containing protein
compare
MMJJ
_RS07480
+0.2
1.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS06120
+0.2
1.6
DUF4013 domain-containing protein
compare
MMJJ
_RS07595
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05605
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS07280
+0.2
1.4
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS02965
+0.2
1.1
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMJJ
_RS03515
+0.2
1.3
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS00155
+0.2
1.7
DUF2193 domain-containing protein
compare
MMJJ
_RS05530
+0.2
0.7
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS01955
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS04850
+0.2
1.4
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS08485
+0.2
0.9
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS06580
+0.2
1.5
alanine dehydrogenase
compare
MMJJ
_RS01970
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06960
+0.2
1.8
CAP domain-containing protein
compare
MMJJ
_RS04390
+0.2
1.6
rhomboid family intramembrane serine protease
compare
MMJJ
_RS08410
+0.2
0.6
CBS domain-containing protein
compare
MMJJ
_RS05520
+0.2
1.5
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS00630
+0.2
1.3
betaine/proline/choline family ABC transporter ATP-binding protein
compare
MMJJ
_RS00405
+0.2
1.0
flavodoxin family protein
compare
MMJJ
_RS03805
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS06430
+0.2
1.2
haloacid dehalogenase
compare
MMJJ
_RS08685
+0.2
1.4
phosphate ABC transporter permease subunit PstC
compare
MMJJ
_RS05980
+0.2
1.3
DUF5400 domain-containing protein
compare
MMJJ
_RS00335
+0.2
0.9
chemotaxis protein CheW
compare
MMJJ
_RS05900
+0.2
1.5
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06540
+0.2
0.7
DUF2120 domain-containing protein
compare
MMJJ
_RS00980
+0.2
1.1
flavodoxin family protein
compare
MMJJ
_RS08350
+0.2
1.6
heavy metal translocating P-type ATPase
compare
MMJJ
_RS02270
+0.2
0.8
HEPN domain-containing protein
compare
MMJJ
_RS03040
+0.2
1.3
lactate utilization protein
compare
MMJJ
_RS07825
+0.2
0.9
YciI family protein
compare
MMJJ
_RS05695
+0.2
0.8
class III signal peptide-containing protein
compare
MMJJ
_RS07820
+0.2
1.4
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS03410
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS06710
+0.2
1.4
TldD/PmbA family protein
compare
MMJJ
_RS05585
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS00320
+0.2
1.0
chemotaxis protein CheD
compare
MMJJ
_RS05500
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS07445
+0.2
1.4
RlmF-related methyltransferase
compare
MMJJ
_RS01800
+0.2
1.3
ADP-ribosylglycohydrolase family protein
compare
MMJJ
_RS07815
+0.2
1.2
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS08285
+0.2
1.4
class I SAM-dependent methyltransferase
compare
MMJJ
_RS00640
+0.2
1.4
glycine betaine ABC transporter substrate-binding protein
compare
MMJJ
_RS03015
+0.2
1.3
Ig-like domain-containing protein
compare
MMJJ
_RS08360
+0.2
1.3
FprA family A-type flavoprotein
compare
MMJJ
_RS01595
+0.2
1.0
U32 family peptidase
compare
MMJJ
_RS06090
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS04385
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05700
+0.2
1.2
metallophosphoesterase
compare
MMJJ
_RS07905
+0.2
1.2
DUF89 domain-containing protein
compare
MMJJ
_RS08560
+0.2
1.1
metal-dependent phosphohydrolase
compare
MMJJ
_RS05690
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS06495
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS03730
+0.2
0.8
SWIM zinc finger family protein
compare
MMJJ
_RS06535
+0.2
1.3
UPF0104 family protein
compare
MMJJ
_RS07200
+0.2
1.3
MFS transporter
compare
MMJJ
_RS05960
+0.2
1.1
DUF169 domain-containing protein
compare
MMJJ
_RS08045
+0.2
1.3
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS04745
+0.2
1.0
cyclase family protein
compare
MMJJ
_RS06235
+0.2
1.3
IGHMBP2 family helicase
compare
MMJJ
_RS00500
+0.2
0.6
GNAT family N-acetyltransferase
compare
MMJJ
_RS03720
+0.2
0.9
DsrE family protein
compare
MMJJ
_RS04345
+0.2
0.7
DUF2080 family transposase-associated protein
compare
MMJJ
_RS07010
+0.2
0.8
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS07255
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS01310
+0.2
1.0
phenylacetate--CoA ligase
compare
MMJJ
_RS06080
+0.2
1.2
serine/threonine protein kinase
compare
MMJJ
_RS07860
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS05510
+0.2
1.1
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS01395
+0.2
0.6
DUF1894 domain-containing protein
compare
MMJJ
_RS00860
+0.2
0.9
4Fe-4S binding protein
compare
MMJJ
_RS06640
+0.2
1.0
YfcE family phosphodiesterase
compare
MMJJ
_RS01825
+0.2
0.8
DNA repair and recombination protein RadB
compare
MMJJ
_RS07805
+0.1
0.8
ferredoxin family protein
compare
MMJJ
_RS07810
+0.1
1.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS05335
+0.1
0.9
heavy metal-binding domain-containing protein
compare
MMJJ
_RS00780
+0.1
1.1
M48 family metallopeptidase
compare
MMJJ
_RS08375
+0.1
1.1
ferritin
compare
MMJJ
_RS04260
+0.1
1.2
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS04510
+0.1
1.2
hypothetical protein
compare
MMJJ
_RS07830
+0.1
1.0
DUF1786 domain-containing protein
compare
MMJJ
_RS09300
+0.1
0.4
hypothetical protein
compare
MMJJ
_RS08890
+0.1
1.3
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS06925
+0.1
0.3
GMP synthase subunit A
compare
MMJJ
_RS04580
+0.1
1.1
2-phosphosulfolactate phosphatase
compare
MMJJ
_RS07680
+0.1
0.9
glucose-6-phosphate isomerase
compare
MMJJ
_RS04500
+0.1
0.9
hypothetical protein
compare
MMJJ
_RS01385
+0.1
1.1
PadR family transcriptional regulator
compare
MMJJ
_RS08030
+0.1
0.9
hypothetical protein
compare
MMJJ
_RS08450
+0.1
0.9
undecaprenyl-diphosphate phosphatase
compare
MMJJ
_RS05505
+0.1
1.3
hypothetical protein
compare
MMJJ
_RS09105
+0.1
1.1
AI-2E family transporter
compare
MMJJ
_RS09005
+0.1
1.2
N-6 DNA methylase
compare
MMJJ
_RS04300
+0.1
0.8
hypothetical protein
compare
MMJJ
_RS07365
+0.1
1.1
CatB-related O-acetyltransferase
compare
MMJJ
_RS06075
+0.1
0.9
DNA-binding protein Alba
compare
MMJJ
_RS06590
+0.1
1.0
sodium:alanine symporter family protein
compare
MMJJ
_RS04120
+0.1
0.8
amino acid ABC transporter ATP-binding protein
compare
MMJJ
_RS01265
+0.1
0.6
cupin domain-containing protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments